Heart Failure Clinical Trials

148 studies are recruiting for heart failure in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 6

1. A Nurse-Led Weight Monitoring Intervention For Heart Failure Quality of LIfe and Self-Care

   Ongoing self-care for heart failure is essential to avoid complications and hospitalization. Supportive strategies are needed; however, patients with heart failure may find many interventions complicated and overwhelming. The purpose of this pilot study is to implement a simple weight tracking tool…

   Stage

   Not phased

   Ages

   55 and older

   Site

   Cleveland Clinic Avon Hospital, Avon, Ohio

   Run by

   Lee Anne Siegmund

   See if you can join NCT07184541 on ClinicalTrials.gov

2. TEXT4HF: A Randomized Controlled Trial of a Tailored Text Messaging Intervention to Improve Self-Care in Older Adult Patients With Heart Failure

   The goal of this study is to determine whether an individually tailored text messaging intervention can improve self-care in older adult patients with heart failure. The main question it aims to answer are: * Is a tailored text messaging intervention feasible and acceptable among older adult patien…

   Stage

   Not phased

   Ages

   50 and older

   Site

   University of Illinois, Chicago, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT06473532 on ClinicalTrials.gov

3. UIC Multi-Ethnic DCM Registry

   Dilated cardiomyopathy (DCM), a condition where the heart loses its ability to pump blood throughout the body, is a common cause of death in the United States (US). It affects minorities more frequently and appears to causes greater harm than Whites. However, almost all research related to DCM has …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Illinois Hospital & Health Sciences, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT07145138 on ClinicalTrials.gov

4. Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients

   Developed nations worldwide are currently enduring a health crisis, as chronic diseases continue to decrease quality of life and promote additional disease states or even death for much of the population. Rural populations are at a particular disadvantage, as they lack access to health clubs, welln…

   Stage

   Not phased

   Ages

   18 to 64

   Site

   West Virginia School of Osteopathic Medicine, Lewisburg, West Virginia

   Run by

   West Virginia School of Osteopathic Medicine

   See if you can join NCT06049420 on ClinicalTrials.gov

5. Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence

   The aim of this study is to evaluate feasibility, efficacy, and adherence of home-based cardiac rehabilitation with the integration of telemedicine. Several components will be assessed such as quality-of-life, nutritional counseling, maximum metabolic activity (MET's), diabetic management, tobacco …

   Stage

   Not phased

   Ages

   18 and older

   Site

   ROMTech, Brookfield, Connecticut

   Run by

   ROM Technologies, INC

   See if you can join NCT05972070 on ClinicalTrials.gov

6. A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System

   The objective of this study is to evaluate the safety and performance of the V-LAP System in subjects with New York Heart Association (NYHA) functional class II and III HF, irrespective of left ventricular ejection fraction.

   Stage

   Not phased

   Ages

   22 to 88

   Site

   One Boston Medical Center Place, Boston, Massachusetts

   Run by

   Vectorious Medical Technologies Ltd.

   See if you can join NCT06147336 on ClinicalTrials.gov

7. Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

   This study aims to determine, via skeletal muscle ultrasound (US), the extent, timing and relationship between skeletal muscle mass loss and outcomes after orthotropic heart transplantation (OHT) and left ventricular assist device (LVAD) implantation amongst patients with cardiogenic shock. Advance…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Tufts Medical Center, Boston, Massachusetts

   Run by

   Tufts Medical Center

   See if you can join NCT06253104 on ClinicalTrials.gov

8. Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues

   Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc. In this imaging technique a person is laid in an MR scanner and a paddle (plastic drum) is put on the area of interest to send sound vibration via a speaker …

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Ohio State University Wexner Medical Center, Columbus, Ohio

   Run by

   Arunark Kolipaka

   See if you can join NCT01757730 on ClinicalTrials.gov

9. Studies of Neuregulin/ERBB Signaling in Human Heart

   This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Maine Medical Center, Portland, Maine

   Run by

   Douglas B. Sawyer

   See if you can join NCT02820233 on ClinicalTrials.gov

10. AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

    Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.

    Stage

    Not phased

    Ages

    22 and older

    Site

    Eastern Shore Research Institute, Fairhope, Alabama

    Locations

    45 in total

    Run by

    Cordio Medical

    See if you can join NCT06378632 on ClinicalTrials.gov

11. Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement

    The goal of PEER-Heart is to implement and assess feasibility and preliminary effectiveness of a community peer-facilitated screening for methamphetamine-associated heart failure (MAHF) and linkage to evidence-based cardiology care for people who use methamphetamine in rural areas.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Oregon Health & Science University, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT06461962 on ClinicalTrials.gov

12. Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)

    This is a prospective, single-arm clinical trial in which participants with dilated cardiomyopathy will invite their first degree relatives to undergo mobile cardiac, electrocardiogram screening.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Lancaster General Hospital, Lancaster, Pennsylvania

    Run by

    Lancaster General Hospital

    See if you can join NCT06688396 on ClinicalTrials.gov

13. Get With The Guidelines-Heart Failure Registry

    Get With The Guidelines-Heart Failure is designed to improve the quality of care in patients hospitalized with heart failure. The program aims to help ensure that eligible patients are initiated on guideline recommended therapies and receive appropriate counseling prior to hospital discharge.

    Stage

    Not phased

    Ages

    18 to 125

    Site

    Amy Bennett, Dallas, Texas

    Run by

    American Heart Association

    See if you can join NCT02693509 on ClinicalTrials.gov

14. Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure

    Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategie…

    Stage

    Not phased

    Ages

    13 to 39

    Site

    Rady Children's Hospital, San Diego, California

    Run by

    Hari Narayan

    See if you can join NCT04262830 on ClinicalTrials.gov

15. Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

    This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.

    Stage

    Not phased

    Ages

    20 to 90

    Site

    UT Southwestern Medical Center, Dallas, Texas

    Locations

    3 in total

    Run by

    Brigham and Women's Hospital

    See if you can join NCT01258231 on ClinicalTrials.gov

16. BiVACOR® Total Artificial Heart Early Feasibility Study

    The purpose of this study is to assess the feasibility of using the BiVACOR Total Artificial Heart (TAH) System to support adult patients with severe biventricular heart failure, or univentricular heart failure in which left ventricular assist device (LVAD) support is not recommended, who require m…

    Stage

    Not phased

    Ages

    18 to 70

    Site

    Banner - University Medical Center Phoenix, Phoenix, Arizona

    Locations

    4 in total

    Run by

    BiVACOR Inc.

    See if you can join NCT06174103 on ClinicalTrials.gov

17. HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

    The purpose of the HF2 (Hemodynamic Frontiers in Heart Failure) registry is to collect relevant patient-level demographic, clinical, laboratory, and hemodynamic data from patients implanted with pulmonary artery pressure sensor at participating centers to advance scientific knowledge about ambulato…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Scripps Health, La Jolla, California

    Locations

    12 in total

    Run by

    University of Kansas Medical Center

    See if you can join NCT06425848 on ClinicalTrials.gov

18. Colchicine in Acutely Decompensated HFREF

    This is a double blind, placebo-controlled pilot trial randomizing patients admitted to the hospital with acutely decompensated heart failure (ADHF) and inflammation to receive either colchicine or matching placebo. Upon enrollment, patients will be randomized 1:1 to receive either the experimental…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    UVA Health, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT06286423 on ClinicalTrials.gov

19. Implantable Cardioverter Defibrillator (ICD Registry)

    The ICD Registry™ is a nationwide quality program that helps participating hospitals measure and improve care for patients receiving implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy devices with defibrillator (CRT-Ds). The ICD Registry captures the characteristic…

    Stage

    Not phased

    Ages

    Any age

    Site

    American College of Cardiology/National Cardiovascular Data Registry (NCDR), Washington D.C., District of Columbia

    Run by

    American College of Cardiology

    See if you can join NCT01999140 on ClinicalTrials.gov

20. Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

    It is believed that targeted SERCA2a enzyme replacement in HFrEF patients will correct defective intracellular Ca2+ hemostasis, resulting in improved cardiac contractile function and energetics which will, in turn, translate to improved clinical outcomes. Additionally, it is hypothesized that corre…

    Stage

    Phase 1

    Ages

    18 to 80

    Site

    San Diego Cardiac Center, San Diego, California

    Locations

    5 in total

    Run by

    Sardocor Corp.

    See if you can join NCT04703842 on ClinicalTrials.gov

21. Care Coordination to Assess Improvement in Outcomes in Hospital Readmissions

    Heart failure is a syndrome that is defined by distinctive clinical, hemodynamic, and neurohormonal findings. HF represents a final common pathway for many different cardiovascular diseases, including coronary disease, hypertension, Valvular disease, and many primary heart muscle diseases. Clinical…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Multiple Locations, Phoenix, Arizona

    Run by

    Aventyn, Inc.

    See if you can join NCT04905160 on ClinicalTrials.gov

22. Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"

    This is an international prospective, multicentre, unblinded, randomised-controlled trial. The primary aim is to assess a targeted screening strategy to detect undiagnosed heart failure in high-risk patients.

    Stage

    Not phased

    Ages

    40 and older

    Site

    University of Glasgow, Glasgow, Scotland

    Locations

    7 in total

    Run by

    NHS Greater Glasgow and Clyde

    See if you can join NCT05919342 on ClinicalTrials.gov

23. Use of ReDS Technology in Patients With Acute Heart Failure

    Background: Fluid overload, especially pulmonary congestion, is one of the main contributors into heart failure (HF) readmission risk and it is a clinical challenge for clinicians. The Remote dielectric sensing (ReDS) system is a novel electromagnetic energy-based technology that can accurately qua…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mount Sinai Hospital, New York, New York

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT04305717 on ClinicalTrials.gov