Heart Failure Clinical Trials in Portland, Oregon

18 studies are recruiting for heart failure in Portland, Oregon right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

  1. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

    The goal of this study is to evaluate the safety and efficacy of the BrioVAD System by demonstrating non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart failure.

    Stage
    Not phased
    Ages
    18 to 100
    Site
    Oregon Health & Science University, Portland, Oregon
    Locations
    47 in total
    Run by
    BrioHealth Solutions, Inc.

    See if you can join NCT06310031 on ClinicalTrials.gov

  2. Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

    The purpose of this study is to find out if the investigational drug called omecamtiv mecarbil can reduce the risk of the effects of heart failure, like hospitalization, transplantation, or death in patients with heart failure and severely reduced ejection fraction.

    Stage
    Phase 3
    Ages
    18 to 85
    Site
    Oregon Health and Science University, Portland, Oregon
    Locations
    205 in total
    Run by
    Cytokinetics

    See if you can join NCT06736574 on ClinicalTrials.gov

  3. Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

    Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated heart failure (ADHF) and have persistent congestion despite usual medical therapy. Eligible ADHF patients with diuretic resistance (irrespective of ejec…

    Stage
    Not phased
    Ages
    21 and older
    Site
    Oregon Health & Sciences University, Portland, Oregon
    Locations
    50 in total
    Run by
    Procyrion

    See if you can join NCT05677100 on ClinicalTrials.gov

  4. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

    Stage
    Not phased
    Ages
    0 to 20
    Site
    Oregon Health and Science University, Portland, Oregon
    Locations
    52 in total
    Run by
    Duke University

    See if you can join NCT04278404 on ClinicalTrials.gov

  5. Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

    The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival probabilities.

    Stage
    Not phased
    Ages
    Any age
    Site
    Research site, Portland, Oregon
    Locations
    333 in total
    Run by
    Medtronic

    See if you can join NCT00271180 on ClinicalTrials.gov

  6. A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

    This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo. The purpose of this clinical study is to f…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Oregon Health & Science University, Portland, Oregon
    Locations
    838 in total
    Run by
    Novo Nordisk A/S

    See if you can join NCT07567001 on ClinicalTrials.gov

  7. Alleviant ALLAY-HF Study

    Prospective, multicenter, randomized, sham-controlled, double blinded, adaptive study designed to evaluate the safety and efficacy of a percutaneously created interatrial shunt using the Alleviant ALV1 System in patients with HFpEF/HFmrEF.

    Stage
    Not phased
    Ages
    40 and older
    Site
    Providence St. Vincent's Medical Center, Portland, Oregon
    Locations
    93 in total
    Run by
    Alleviant Medical, Inc.

    See if you can join NCT05685303 on ClinicalTrials.gov

  8. CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

    The purpose of this multi-center clinical trial is to study the efficacy and safety of providing nutritional support added to the study-defined standard of care which consists of standardized dietary education and a single dietary counseling session shortly after discharge, versus study-defined sta…

    Stage
    Not phased
    Ages
    60 and older
    Site
    VA Portland Health Care System, Portland, OR, Portland, Oregon
    Locations
    16 in total
    Run by
    VA Office of Research and Development

    See if you can join NCT05996328 on ClinicalTrials.gov

  9. Assessment of CCM in HF With Higher Ejection Fraction

    The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤70%.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Providence Heart & Vascular, Portland, Oregon
    Locations
    105 in total
    Run by
    Impulse Dynamics

    See if you can join NCT05064709 on ClinicalTrials.gov

  10. A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

    This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure. Participants will either get CDR132L or placebo (a medicine which has no effect on the body), which treatment the participants get is decided by cha…

    Stage
    Phase 2
    Ages
    40 to 84
    Site
    Providence St. Vincent Heart, Portland, Oregon
    Locations
    117 in total
    Run by
    Novo Nordisk A/S

    See if you can join NCT06979362 on ClinicalTrials.gov

  11. PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

    This is a prospective, multi-center, open label, randomized control clinical trial evaluating the safety and efficacy of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial). The study contains of 5 arms: NYHA II Cohort - To demonstrate saf…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Providence St. Vincent's - Portland, Portland, Oregon
    Locations
    48 in total
    Run by
    Endotronix, Inc.

    See if you can join NCT05934487 on ClinicalTrials.gov

  12. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

    The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Oregon Health & Science University, Portland, Oregon
    Locations
    68 in total
    Run by
    Abbott Medical Devices

    See if you can join NCT06526195 on ClinicalTrials.gov

  13. CCM OPEN HF Registry

    The registry has been designed to evaluate the long-term safety and efficacy of CCM therapy in a real-world setting.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Providence St. Vincent Medical Center, Portland, Oregon
    Locations
    28 in total
    Run by
    Impulse Dynamics

    See if you can join NCT07112924 on ClinicalTrials.gov

  14. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).

    Stage
    Not phased
    Ages
    18 and older
    Site
    Oregon Health & Science University (OHSU), Portland, Oregon
    Locations
    92 in total
    Run by
    Cardiac Dimensions, Inc.

    See if you can join NCT03142152 on ClinicalTrials.gov

  15. Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

    Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Whether these drugs have similar effects in patients with type 1 diabetes (T1D) remains unknown because …

    Stage
    Phase 3
    Ages
    18 to 75
    Site
    Oregon Health and Science University, Portland, Oregon
    Locations
    19 in total
    Run by
    Alessandro Doria

    See if you can join NCT06217302 on ClinicalTrials.gov

  16. Left vs Left Randomized Clinical Trial

    The investigators aim to prospectively test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failure hospitalization, mortality) and comparative safety in relation to device-related complications an…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Oregon Health & Science University, Portland, Oregon
    Locations
    71 in total
    Run by
    Baylor College of Medicine

    See if you can join NCT05650658 on ClinicalTrials.gov

  17. Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement

    The goal of PEER-Heart is to implement and assess feasibility and preliminary effectiveness of a community peer-facilitated screening for methamphetamine-associated heart failure (MAHF) and linkage to evidence-based cardiology care for people who use methamphetamine in rural areas.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Oregon Health & Science University, Portland, Oregon
    Run by
    Oregon Health and Science University

    See if you can join NCT06461962 on ClinicalTrials.gov

  18. HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

    The purpose of the HF2 (Hemodynamic Frontiers in Heart Failure) registry is to collect relevant patient-level demographic, clinical, laboratory, and hemodynamic data from patients implanted with pulmonary artery pressure sensor at participating centers to advance scientific knowledge about ambulato…

    Stage
    Not phased
    Ages
    18 to 100
    Site
    Providence Heart Institute, Portland, Oregon
    Locations
    12 in total
    Run by
    University of Kansas Medical Center

    See if you can join NCT06425848 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.