Heart Failure Clinical Trials in Kansas City, Missouri

16 studies are recruiting for heart failure in Kansas City, Missouri right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

    Participants include men and women ≥ 40 years of age with T2DM, established CV disease, a history of HTN with an SBP of at least 130 mmHg at screening, who meet the predefined serum potassium level, and with at least one additional risk factor for HF. The study will include an optional pre-screenin…

    Stage
    Phase 3
    Ages
    40 and older
    Site
    Research Site, Kansas City, Missouri
    Locations
    957 in total
    Run by
    AstraZeneca

    See if you can join NCT06677060 on ClinicalTrials.gov

  2. A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

    Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Kansas City, MO Investigative Site 10002, Kansas City, Missouri
    Locations
    356 in total
    Run by
    Colorado Prevention Center

    See if you can join NCT06008197 on ClinicalTrials.gov

  3. A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

    Combination therapy of finerenone plus empagliflozin will be compared to usual care to determine the efficacy and safety of treatment in patients hospitalized with heart failure.

    Stage
    Phase 3
    Ages
    18 and older
    Site
    CON-10002 Kansas City, MO Investigative Site, Kansas City, Missouri
    Locations
    140 in total
    Run by
    Colorado Prevention Center

    See if you can join NCT06024746 on ClinicalTrials.gov

  4. The WiSE®-UP Study (The WiSE System Utilization & Performance Study)

    Observe to understand product performance, including patient safety, clinical outcomes, and CRT response information associated with the use of the market-released WiSE System

    Stage
    Not phased
    Ages
    22 and older
    Site
    St. Luke's Hospital of Kansas City, Kansas City, Missouri
    Locations
    12 in total
    Run by
    EBR Systems, Inc.

    See if you can join NCT07098858 on ClinicalTrials.gov

  5. A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

    This study is open to adults with chronic heart failure (HF) who have a reduced left ventricular ejection fraction (LVEF) of less than 40%. People can join the study if they have been diagnosed with chronic HF at least 3 months before they start on the study. The purpose of this study is to find ou…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Kansas City VA Medical Center, Kansas City, Missouri
    Locations
    588 in total
    Run by
    Boehringer Ingelheim

    See if you can join NCT06935370 on ClinicalTrials.gov

  6. Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

    The purpose of this study is to find out if the investigational drug called omecamtiv mecarbil can reduce the risk of the effects of heart failure, like hospitalization, transplantation, or death in patients with heart failure and severely reduced ejection fraction.

    Stage
    Phase 3
    Ages
    18 to 85
    Site
    Saint Luke's Hospital of Kansas City, Kansas City, Missouri
    Locations
    205 in total
    Run by
    Cytokinetics

    See if you can join NCT06736574 on ClinicalTrials.gov

  7. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

    Stage
    Not phased
    Ages
    0 to 20
    Site
    Children's Mercy Hospital, Kansas City, Missouri
    Locations
    52 in total
    Run by
    Duke University

    See if you can join NCT04278404 on ClinicalTrials.gov

  8. A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

    This study is open to adults aged 18 or above legal age with heart failure. People can join the study if they have heart failure symptoms and a left ventricular ejection fraction (LVEF) of 40% or more. The purpose of this study is to find out whether vicadrostat (BI 690517) in combination with empa…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Kansas City VA Medical Center, Kansas City, Missouri
    Locations
    652 in total
    Run by
    Boehringer Ingelheim

    See if you can join NCT06424288 on ClinicalTrials.gov

  9. Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

    The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival probabilities.

    Stage
    Not phased
    Ages
    Any age
    Site
    Research site, Kansas City, Missouri
    Locations
    333 in total
    Run by
    Medtronic

    See if you can join NCT00271180 on ClinicalTrials.gov

  10. A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

    This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo. The purpose of this clinical study is to f…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Clinical Research Consultants, JCCT Co, Kansas City, Missouri
    Locations
    838 in total
    Run by
    Novo Nordisk A/S

    See if you can join NCT07567001 on ClinicalTrials.gov

  11. Assessment of CCM in HF With Higher Ejection Fraction

    The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤70%.

    Stage
    Not phased
    Ages
    18 and older
    Site
    St. Lukes Hospital Kansas City (Mid America Heart Institute), Kansas City, Missouri
    Locations
    105 in total
    Run by
    Impulse Dynamics

    See if you can join NCT05064709 on ClinicalTrials.gov

  12. A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

    Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients with heart failure and reduced ejection fraction (HFrEF) who are intolerant or ineligible to receive treatment with steroidal mineralocorticoid receptor antagonists (sMRA).

    Stage
    Phase 3
    Ages
    18 and older
    Site
    FIN-10002 Kansas City, MO Investigational Site, Kansas City, Missouri
    Locations
    176 in total
    Run by
    Colorado Prevention Center

    See if you can join NCT06033950 on ClinicalTrials.gov

  13. PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

    This is a prospective, multi-center, open label, randomized control clinical trial evaluating the safety and efficacy of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial). The study contains of 5 arms: NYHA II Cohort - To demonstrate saf…

    Stage
    Not phased
    Ages
    18 and older
    Site
    St. Lukes/ Mid-American Heart Institute, Kansas City, Missouri
    Locations
    48 in total
    Run by
    Endotronix, Inc.

    See if you can join NCT05934487 on ClinicalTrials.gov

  14. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

    The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.

    Stage
    Not phased
    Ages
    18 and older
    Site
    St. Luke's Hospital, Kansas City, Missouri
    Locations
    68 in total
    Run by
    Abbott Medical Devices

    See if you can join NCT06526195 on ClinicalTrials.gov

  15. CCM OPEN HF Registry

    The registry has been designed to evaluate the long-term safety and efficacy of CCM therapy in a real-world setting.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Saint Luke's Hospital Mid America Heart Institute, Kansas City, Missouri
    Locations
    28 in total
    Run by
    Impulse Dynamics

    See if you can join NCT07112924 on ClinicalTrials.gov

  16. HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

    The purpose of the HF2 (Hemodynamic Frontiers in Heart Failure) registry is to collect relevant patient-level demographic, clinical, laboratory, and hemodynamic data from patients implanted with pulmonary artery pressure sensor at participating centers to advance scientific knowledge about ambulato…

    Stage
    Not phased
    Ages
    18 to 100
    Site
    Saint Luke's Health System, Kansas City, Missouri
    Locations
    12 in total
    Run by
    University of Kansas Medical Center

    See if you can join NCT06425848 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.