Heart Failure Clinical Trials in Charlottesville, Virginia

10 studies are recruiting for heart failure in Charlottesville, Virginia right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

   Participants include men and women ≥ 40 years of age with T2DM, established CV disease, a history of HTN with an SBP of at least 130 mmHg at screening, who meet the predefined serum potassium level, and with at least one additional risk factor for HF. The study will include an optional pre-screenin…

   Stage

   Phase 3

   Ages

   40 and older

   Site

   Research Site, Charlottesville, Virginia

   Locations

   957 in total

   Run by

   AstraZeneca

   See if you can join NCT06677060 on ClinicalTrials.gov

2. The WiSE®-UP Study (The WiSE System Utilization & Performance Study)

   Observe to understand product performance, including patient safety, clinical outcomes, and CRT response information associated with the use of the market-released WiSE System

   Stage

   Not phased

   Ages

   22 and older

   Site

   UVA, Charlottesville, Virginia

   Locations

   12 in total

   Run by

   EBR Systems, Inc.

   See if you can join NCT07098858 on ClinicalTrials.gov

3. Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

   Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated heart failure (ADHF) and have persistent congestion despite usual medical therapy. Eligible ADHF patients with diuretic resistance (irrespective of ejec…

   Stage

   Not phased

   Ages

   21 and older

   Site

   University of Virginia, Charlottesville, Virginia

   Locations

   50 in total

   Run by

   Procyrion

   See if you can join NCT05677100 on ClinicalTrials.gov

4. Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

   The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival probabilities.

   Stage

   Not phased

   Ages

   Any age

   Site

   Research site, Charlottesville, Virginia

   Locations

   333 in total

   Run by

   Medtronic

   See if you can join NCT00271180 on ClinicalTrials.gov

5. A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

   This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo. The purpose of this clinical study is to f…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   University Of Virginia Hospital, Charlottesville, Virginia

   Locations

   838 in total

   Run by

   Novo Nordisk A/S

   See if you can join NCT07567001 on ClinicalTrials.gov

6. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

   The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Virginia Medical Center, Charlottesville, Virginia

   Locations

   68 in total

   Run by

   Abbott Medical Devices

   See if you can join NCT06526195 on ClinicalTrials.gov

7. Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)

   The purpose of this study is to demonstrate the safety and effectiveness of the VDI UHF-ECG System in the diagnosis of ventricular dyssynchrony when compared to the 12-lead ECG in patients with bradycardia and heart failure indicated for pacemaker implantation.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Virginia, Charlottesville, Virginia

   Locations

   12 in total

   Run by

   VDI Technologies

   See if you can join NCT06641362 on ClinicalTrials.gov

8. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

   The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Virginia Health System, Charlottesville, Virginia

   Locations

   92 in total

   Run by

   Cardiac Dimensions, Inc.

   See if you can join NCT03142152 on ClinicalTrials.gov

9. Left vs Left Randomized Clinical Trial

   The investigators aim to prospectively test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failure hospitalization, mortality) and comparative safety in relation to device-related complications an…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Virginia Health System, Charlottesville, Virginia

   Locations

   71 in total

   Run by

   Baylor College of Medicine

   See if you can join NCT05650658 on ClinicalTrials.gov

10. Colchicine in Acutely Decompensated HFREF

    This is a double blind, placebo-controlled pilot trial randomizing patients admitted to the hospital with acutely decompensated heart failure (ADHF) and inflammation to receive either colchicine or matching placebo. Upon enrollment, patients will be randomized 1:1 to receive either the experimental…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    UVA Health, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT06286423 on ClinicalTrials.gov