Ulcerative Colitis Clinical Trials

47 studies are recruiting for ulcerative colitis in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

   The main aim of this study is to learn about medical problems (adverse events) if vedolizumab subcutaneously (SC) is given to a child or teenager with UC or CD for a long time. Other aims are to understand if the long time use of vedolizumab SC has an impact on the time period until hospital visits…

   Stage

   Phase 3

   Ages

   2 to 17

   Site

   The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

   Locations

   54 in total

   Run by

   Takeda

   See if you can join NCT06405087 on ClinicalTrials.gov

2. A Study of Ozanimod in Pregnant Women With Ulcerative Colitis and Their Offspring

   The purpose of this study is to evaluate association between ozanimod exposure during pregnancy and subsequent maternal, fetal, and infant outcomes.

   Stage

   Not phased

   Ages

   Any age

   Site

   PPD Virtual - PPD - US, Wilmington, North Carolina

   Run by

   Bristol-Myers Squibb

   See if you can join NCT05953402 on ClinicalTrials.gov

3. R-3750 in Patients With Mild to Moderate Ulcerative Colitis

   The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-3750) in patients with mild to moderate ulcerative colitis. Patients will take an oral dosage of probiotic (R-3750) and provide patient-reported and physician scored measures of their colitis. Blood and …

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   Amicis Research Center, Valencia, California

   Locations

   5 in total

   Run by

   Rise Therapeutics LLC

   See if you can join NCT05666960 on ClinicalTrials.gov

4. The Use of Butyrate Therapy in Pediatric Ulcerative Colitis

   Butyrate is an important metabolite produced by the gut microbiome and has been shown as a helpful therapy in ulcerative colitis. This is a feasibility study to determine the efficacy of butryate enemas in pediatric ulcerative colitis.

   Stage

   Phase 2

   Ages

   7 to 21

   Site

   Children's Hospital Los Angeles, Los Angeles, California

   Run by

   Children's Hospital Los Angeles

   See if you can join NCT05218850 on ClinicalTrials.gov

5. A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

   Crohn's Disease and Ulcerative Colitis are two types of inflammatory bowel disease (IBD), which is a serious, long-term condition in the gut (intestine) that can cause pain and swelling (inflammation) in the bowel. TAK-279 is a medicine which helps to block inflammation. This study is an extension …

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Woodholme Gastroenterology Associates, Glen Burnie, Maryland

   Locations

   16 in total

   Run by

   Takeda

   See if you can join NCT06764615 on ClinicalTrials.gov

6. Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

   This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who receive or will receive immune checkpoint inhibitor drugs. Patients will be asked their opinions about the design, accessibility, and content of …

   Stage

   Not phased

   Ages

   18 and older

   Site

   M D Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT04751396 on ClinicalTrials.gov

7. A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

   The study is an extension of two parent studies (MLN0002-3024 [NCT04779307] and MLN0002-3025 [NCT04779320]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.

   Stage

   Phase 3

   Ages

   2 and older

   Site

   Phoenix Childrens Hospital - Thomas Rd - PIN, Phoenix, Arizona

   Locations

   98 in total

   Run by

   Takeda

   See if you can join NCT05442567 on ClinicalTrials.gov

8. Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

   This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut in…

   Stage

   Not phased

   Ages

   6 to 21

   Site

   Seattle Children's Hospital, Seattle, Washington

   Run by

   Seattle Children's Hospital

   See if you can join NCT06315179 on ClinicalTrials.gov

9. A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

   This is a phase 2b, randomized, double-blind, 3-arm study for the treatment of Ulcerative Colitis. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Ulcerative Colitis. The total study duration…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Investigational Site Number: 8400009, Escondido, California

   Locations

   67 in total

   Run by

   Sanofi

   See if you can join NCT06975722 on ClinicalTrials.gov

10. Patient Preference for Subcutaneous vs. Intravenous Immune Therapy

    The study will evaluate patient and Health Care Professional- reported preference for Subcutaneous (SC) compared with IV nivolumab administration or similarly for SC compared with IV pembrolizumab.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania

    Run by

    Diwakar Davar

    See if you can join NCT07223424 on ClinicalTrials.gov

11. Tailored Anti-Inflammatory (A-I) Diet for Americans With Ulcerative Colitis (UC)

    The purpose of this study is to test the effect of an anti-inflammatory diet that incorporates native foods of the American diet on disease remission in American patients with Ulcerative Colitis (UC) and to identify biomarkers of response to dietary therapy.

    Stage

    Not phased

    Ages

    16 to 75

    Site

    University of Miami Health System, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT06784323 on ClinicalTrials.gov

12. The Influence of a Fasting Mimicking Diet on Ulcerative Colitis

    The purpose of this study is to see how a diet that mimics fasting effects inflammation in patients with mild to moderate Ulcerative Colitis (UC). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized…

    Stage

    Not phased

    Ages

    18 to 70

    Site

    Stanford University, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT03615690 on ClinicalTrials.gov

13. Fermented Food-Supplemented Diet in Ulcerative Colitis

    The purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal inflammation. Ferme…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Stanford University, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT04401605 on ClinicalTrials.gov

14. Impact of Prebiotics in Ulcerative Colitis

    The cause of inflammatory bowel disease (IBD) is currently unknown, although partly attributed to interactions among genetic risk polymorphisms, environmental factors, gut microbiome, and host immunity. Diet, particularly those with plant-based products, have been shown in prior research to improve…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    UCLA, Los Angeles, California

    Run by

    University of California, Los Angeles

    See if you can join NCT06495658 on ClinicalTrials.gov

15. Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

    Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen under increased atmospheric pressure to increase tissue oxygenation. Two small prospective randomized controlled trials have dem…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    University of Alabama Medicine, Birmingham, Alabama

    Locations

    13 in total

    Run by

    Northwestern University

    See if you can join NCT05987852 on ClinicalTrials.gov

16. Study of Novel Therapeutics for Acute Remedy of Colitis

    This study is a clinical trial being done to investigate the efficacy of drug BRS201 as a treatment in patients with acute ulcerative colitis. Patients who qualify are adults who have not responded to treatments for their severe ulcerative colitis. Participation in this study will take 12 weeks lon…

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    Brigham and Women's Hospital, Chestnut Hill, Massachusetts

    Locations

    2 in total

    Run by

    Brigham and Women's Hospital

    See if you can join NCT06420492 on ClinicalTrials.gov

17. Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis

    This is a randomized, double-blind, placebo-controlled, multicenter, study to evaluate the efficacy, safety, and pharmacokinetics (PK) of budesonide extended-release tablets for the induction of remission in pediatric subjects, with active, mild to moderate ulcerative colitis (UC). Subjects will be…

    Stage

    Phase 4

    Ages

    5 to 17

    Site

    Bausch Health Site 008, Garden Grove, California

    Locations

    4 in total

    Run by

    Bausch Health Americas, Inc.

    See if you can join NCT04314375 on ClinicalTrials.gov

18. Mirikizumab Real World Protocol

    The goal of this observational study is to learn about how effective mirikizumab (Omvoh) is when treating patients with ulcerative colitis (UC) Does mirikizumab (Omvoh) lead to a reduction in symptoms at intervals throughout one year? Participants being prescribed mirikizumab (Omvoh) as part of the…

    Stage

    Not phased

    Ages

    18 and older

    Site

    South Denver Gastroenterology, Denver, Colorado

    Locations

    9 in total

    Run by

    University of North Carolina, Chapel Hill

    See if you can join NCT06696014 on ClinicalTrials.gov

19. Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

    The goal of this observational study is to assess the feasibility and effectiveness of a remote monitoring digital health system on adherence, clinical outcomes, and healthcare utilization in patients with inflammatory bowel disease (Crohn's disease, ulcerative colitis, and inflammatory bowel disea…

    Stage

    Not phased

    Ages

    18 and older

    Site

    New York University, New York, New York

    Locations

    6 in total

    Run by

    Mercy Medical Center

    See if you can join NCT06750731 on ClinicalTrials.gov

20. High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

    The investigators will be administering oral high dose interval vitamin D, concurrently when participants are receiving biologic therapy for their inflammatory bowel disease. The investigators will be collecting some additional bloodwork and questionnaires at the time of participants infusions.

    Stage

    Not phased

    Ages

    5 to 25

    Site

    Boston Children's Hospital, Boston, Massachusetts

    Run by

    Boston Children's Hospital

    See if you can join NCT04331639 on ClinicalTrials.gov

21. Understanding Ozanimod's MOA Via Mass Cytometry in Ulcerative Colitis

    The goal of this observational study is to learn about the mechanism of action of ozanimod in patients with ulcerative colitis (UC). The main questions it aims to answer are: 1. Prospectively assess the effects of ozanimod on the cellular composition of intestinal lamina propria and blood by deep i…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of California San Diego, San Diego, California

    Run by

    University of California, San Diego

    See if you can join NCT06311123 on ClinicalTrials.gov

22. Registry and Biorepository for IBD in Central Texas

    This is a prospective, non-interventional registry and biorepository for patients with IBD. Longitudinal follow-up data is collected from both patients and their treating gastroenterologist during routine clinical encounters. The biorepository will consist of prospective collection of blood samples…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Dell Medical School, UT Austin, Austin, Texas

    Run by

    University of Texas at Austin

    See if you can join NCT04617184 on ClinicalTrials.gov