Ulcerative Colitis Clinical Trials in Los Angeles, California

9 studies are recruiting for ulcerative colitis in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

   The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compared to mirikizumab alone in adult participants with moderately to severely active ulcerative colitis (UC). Study participation will last approximately 118 weeks, including 104 wee…

   Stage

   Phase 2

   Ages

   18 to 80

   Site

   Biopharma Informatic, LLC, Los Angeles, California

   Locations

   147 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07186101 on ClinicalTrials.gov

2. An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

   This is a multinational, multicenter, randomized, double-blind, placebo-controlled, Phase 3 induction study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Ulcerative Colitis (UC). Study details include: The study duration may be up to 35 weeks wi…

   Stage

   Phase 3

   Ages

   16 to 80

   Site

   TLC Clinical Research Inc. - Site Number: 8400030, Los Angeles, California

   Locations

   219 in total

   Run by

   Sanofi

   See if you can join NCT07184996 on ClinicalTrials.gov

3. A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

   The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis (UC). Another aim is to learn about treatment with Vedolizumab alone after the double treatment. All participants wi…

   Stage

   Phase 4

   Ages

   18 to 65

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   46 in total

   Run by

   Takeda

   See if you can join NCT06095128 on ClinicalTrials.gov

4. Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

   The purpose of this study is to compare the effectiveness and safety of a strategy of switching to an alternative targeted immunomodulator (TIM) therapy to treat to a target of endoscopic remission, versus continuing index TIM in patients with inflammatory bowel disease (IBD) (Crohn's disease or ul…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai, Los Angeles, California

   Locations

   24 in total

   Run by

   Mayo Clinic

   See if you can join NCT05230173 on ClinicalTrials.gov

5. BOOM-IBD2 Pivotal Clinical Trial

   Ulcerative colitis is a long-lasting condition that causes swelling and sores in the large intestine. This study tests whether a small device placed under the skin can help reduce bowel urgency in people with ulcerative colitis. The investigational device sends mild signals to a nerve near the tail…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Center for Colorectal Innovation, Los Angeles, California

   Locations

   19 in total

   Run by

   Boomerang Medical

   See if you can join NCT06571669 on ClinicalTrials.gov

6. The Use of Butyrate Therapy in Pediatric Ulcerative Colitis

   Butyrate is an important metabolite produced by the gut microbiome and has been shown as a helpful therapy in ulcerative colitis. This is a feasibility study to determine the efficacy of butryate enemas in pediatric ulcerative colitis.

   Stage

   Phase 2

   Ages

   7 to 21

   Site

   Children's Hospital Los Angeles, Los Angeles, California

   Run by

   Children's Hospital Los Angeles

   See if you can join NCT05218850 on ClinicalTrials.gov

7. A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

   The study is an extension of two parent studies (MLN0002-3024 [NCT04779307] and MLN0002-3025 [NCT04779320]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.

   Stage

   Phase 3

   Ages

   2 and older

   Site

   Cedars Sinai Medical Center - 127 San Vicente Blvd, Los Angeles, California

   Locations

   98 in total

   Run by

   Takeda

   See if you can join NCT05442567 on ClinicalTrials.gov

8. Impact of Prebiotics in Ulcerative Colitis

   The cause of inflammatory bowel disease (IBD) is currently unknown, although partly attributed to interactions among genetic risk polymorphisms, environmental factors, gut microbiome, and host immunity. Diet, particularly those with plant-based products, have been shown in prior research to improve…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   UCLA, Los Angeles, California

   Run by

   University of California, Los Angeles

   See if you can join NCT06495658 on ClinicalTrials.gov

9. Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

   Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen under increased atmospheric pressure to increase tissue oxygenation. Two small prospective randomized controlled trials have dem…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   University of Los Angeles Health, Los Angeles, California

   Locations

   13 in total

   Run by

   Northwestern University

   See if you can join NCT05987852 on ClinicalTrials.gov