Ulcerative Colitis Clinical Trials in Louisville, Kentucky

7 studies are recruiting for ulcerative colitis in Louisville, Kentucky right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

   Crohn's disease (CD) and Ulcerative colitis (UC) are 2 types of inflammatory bowel diseases which cause long-lasting, severe inflammation (redness, swelling) in the digestive tract. CD can affect any part of the digestive tract causing many different symptoms including belly pain, diarrhea, tiredne…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Gastroenterology Health Partners /ID# 284144, Louisville, Kentucky

   Locations

   36 in total

   Run by

   AbbVie

   See if you can join NCT07697456 on ClinicalTrials.gov

2. LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

   The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compared to mirikizumab alone in adult participants with moderately to severely active ulcerative colitis (UC). Study participation will last approximately 118 weeks, including 104 wee…

   Stage

   Phase 2

   Ages

   18 to 80

   Site

   Gastroenterology Health Partners, Louisville, Kentucky

   Locations

   147 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07186101 on ClinicalTrials.gov

3. Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

   The main purpose of this study is to show whether in these individuals, treatment with both mirikizumab and tirzepatide, compared with treatment with mirikizumab and placebo, leads to decrease or disappearance of UC symptoms, and loss of at least one-tenth of the overall body weight. Participation …

   Stage

   Phase 3

   Ages

   18 to 70

   Site

   Gastroenterology Health Partners, Louisville, Kentucky

   Locations

   187 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT06937086 on ClinicalTrials.gov

4. A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

   This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficacy and safety of multiple interventions following intravenous (IV) induction and subcutaneous (SC) m…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Site 030, Louisville, Kentucky

   Locations

   267 in total

   Run by

   Spyre Therapeutics, Inc.

   See if you can join NCT07012395 on ClinicalTrials.gov

5. A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

   The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis (UC). Another aim is to learn about treatment with Vedolizumab alone after the double treatment. All participants wi…

   Stage

   Phase 4

   Ages

   18 to 65

   Site

   University of Louisville, Louisville, Kentucky

   Locations

   46 in total

   Run by

   Takeda

   See if you can join NCT06095128 on ClinicalTrials.gov

6. Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

   Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen under increased atmospheric pressure to increase tissue oxygenation. Two small prospective randomized controlled trials have dem…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   University of Louisville, Louisville, Kentucky

   Locations

   13 in total

   Run by

   Northwestern University

   See if you can join NCT05987852 on ClinicalTrials.gov

7. Mirikizumab Real World Protocol

   The goal of this observational study is to learn about how effective mirikizumab (Omvoh) is when treating patients with ulcerative colitis (UC) Does mirikizumab (Omvoh) lead to a reduction in symptoms at intervals throughout one year? Participants being prescribed mirikizumab (Omvoh) as part of the…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Louisville, Clinical Trials Unit, Louisville, Kentucky

   Locations

   9 in total

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT06696014 on ClinicalTrials.gov