Ulcerative Colitis Clinical Trials in Pittsburgh, Pennsylvania

6 studies are recruiting for ulcerative colitis in Pittsburgh, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

   Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will assess how Risankizumab moves through the body as well as how safe and effective it is in treating pediatric participants …

   Stage

   Phase 3

   Ages

   2 to 17

   Site

   Upmc Children'S Hospital Of Pittsburgh /ID# 272328, Pittsburgh, Pennsylvania

   Locations

   64 in total

   Run by

   AbbVie

   See if you can join NCT07071519 on ClinicalTrials.gov

2. Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

   This phase Ib trial studies the side effects of nivolumab and to see how well it works alone and in combination with other treatments, such as ipilimumab, cabozantinib, platinum containing therapy, and fluoropyrimidine, in treating patients with autoimmune disorders and cancer that has spread from …

   Stage

   Phase 1

   Ages

   18 and older

   Site

   UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania

   Locations

   52 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT03816345 on ClinicalTrials.gov

3. An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

   This is a multinational, multicenter, randomized, double-blind, placebo-controlled, Phase 3 induction study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Ulcerative Colitis (UC). Study details include: The study duration may be up to 35 weeks wi…

   Stage

   Phase 3

   Ages

   16 to 80

   Site

   The Allegheny Health Network (AHN) Center for Digestive Health - Site Number: 8400107, Pittsburgh, Pennsylvania

   Locations

   219 in total

   Run by

   Sanofi

   See if you can join NCT07184996 on ClinicalTrials.gov

4. A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

   The study is an extension of two parent studies (MLN0002-3024 [NCT04779307] and MLN0002-3025 [NCT04779320]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.

   Stage

   Phase 3

   Ages

   2 and older

   Site

   UPMC Children's Hospital of Pittsburgh - Adolescent Medicine (Oakland) - PIN, Pittsburgh, Pennsylvania

   Locations

   98 in total

   Run by

   Takeda

   See if you can join NCT05442567 on ClinicalTrials.gov

5. Patient Preference for Subcutaneous vs. Intravenous Immune Therapy

   The study will evaluate patient and Health Care Professional- reported preference for Subcutaneous (SC) compared with IV nivolumab administration or similarly for SC compared with IV pembrolizumab.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania

   Run by

   Diwakar Davar

   See if you can join NCT07223424 on ClinicalTrials.gov

6. Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

   Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen under increased atmospheric pressure to increase tissue oxygenation. Two small prospective randomized controlled trials have dem…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Allegheny Health, Pittsburgh, Pennsylvania

   Locations

   13 in total

   Run by

   Northwestern University

   See if you can join NCT05987852 on ClinicalTrials.gov