Ulcerative Colitis Clinical Trials in Chapel Hill, North Carolina

8 studies are recruiting for ulcerative colitis in Chapel Hill, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

   This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficacy and safety of multiple interventions following intravenous (IV) induction and subcutaneous (SC) m…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   040, Chapel Hill, North Carolina

   Locations

   267 in total

   Run by

   Spyre Therapeutics, Inc.

   See if you can join NCT07012395 on ClinicalTrials.gov

2. An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

   This is a multinational, multicenter, randomized, double-blind, placebo-controlled, Phase 3 induction study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Ulcerative Colitis (UC). Study details include: The study duration may be up to 35 weeks wi…

   Stage

   Phase 3

   Ages

   16 to 80

   Site

   UNC Hospitals, The University of North Carolina at Chapel Hill - Site Number: 8400074, Chapel Hill, North Carolina

   Locations

   219 in total

   Run by

   Sanofi

   See if you can join NCT07184996 on ClinicalTrials.gov

3. A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

   The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis (UC). Another aim is to learn about treatment with Vedolizumab alone after the double treatment. All participants wi…

   Stage

   Phase 4

   Ages

   18 to 65

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   46 in total

   Run by

   Takeda

   See if you can join NCT06095128 on ClinicalTrials.gov

4. BOOM-IBD2 Pivotal Clinical Trial

   Ulcerative colitis is a long-lasting condition that causes swelling and sores in the large intestine. This study tests whether a small device placed under the skin can help reduce bowel urgency in people with ulcerative colitis. The investigational device sends mild signals to a nerve near the tail…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   UNC Chapel Hill, Chapel Hill, North Carolina

   Locations

   19 in total

   Run by

   Boomerang Medical

   See if you can join NCT06571669 on ClinicalTrials.gov

5. A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

   The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC).

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   207 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT06598943 on ClinicalTrials.gov

6. A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

   This is a phase 2b, randomized, double-blind, 3-arm study for the treatment of Ulcerative Colitis. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Ulcerative Colitis. The total study duration…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Investigational Site Number: 8400002, Chapel Hill, North Carolina

   Locations

   67 in total

   Run by

   Sanofi

   See if you can join NCT06975722 on ClinicalTrials.gov

7. Mirikizumab Real World Protocol

   The goal of this observational study is to learn about how effective mirikizumab (Omvoh) is when treating patients with ulcerative colitis (UC) Does mirikizumab (Omvoh) lead to a reduction in symptoms at intervals throughout one year? Participants being prescribed mirikizumab (Omvoh) as part of the…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   9 in total

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT06696014 on ClinicalTrials.gov

8. Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

   The goal of this observational study is to assess the feasibility and effectiveness of a remote monitoring digital health system on adherence, clinical outcomes, and healthcare utilization in patients with inflammatory bowel disease (Crohn's disease, ulcerative colitis, and inflammatory bowel disea…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   6 in total

   Run by

   Mercy Medical Center

   See if you can join NCT06750731 on ClinicalTrials.gov