Opioid Use Disorder Clinical Trials

135 studies are recruiting for opioid use disorder in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 6

1. AvertD Post-Approval Study

   A Prospective Post-Approval Study of AvertD to Evaluate Device Performance, Prescribing Impact, and Labeling Comprehension in the Intended Use Population

   Stage

   Not phased

   Ages

   18 and older

   Site

   Concentrics Research, Indianapolis, Indiana

   Run by

   Prescient Medicine Holdings, Inc.

   See if you can join NCT07135323 on ClinicalTrials.gov

2. Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder

   The US is currently going through an opioid crisis, and while Medication Assisted Treatments such as buprenorphine (BUP) have proved highly effective at stabilizing the neurobiology underlying acute withdrawal, they have been less effective at preventing longer-term relapse and adherence. This may …

   Stage

   Phase 1

   Ages

   18 to 55

   Site

   Rutgers School of Health Professions, Newark, New Jersey

   Run by

   Rutgers, The State University of New Jersey

   See if you can join NCT06642181 on ClinicalTrials.gov

3. Disclosure Intervention for People in Treatment for Opioid Use Disorder

   The goal of this clinical trial is to test a disclosure intervention among people in treatment for opioid use disorder. The main question it aims to answer is whether people who receive a disclosure intervention have better treatment- and recovery-related outcomes one year after receiving the inter…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brandywine Counseling & Community Services, Wilmington, Delaware

   Run by

   University of Delaware

   See if you can join NCT06458985 on ClinicalTrials.gov

4. Opioid Treatment and Peer Recovery Support

   Determine whether a facilitated local change team intervention improves a probation organization's client-level medication for opioid use disorder (MOUD) outcomes and implementation outcomes relative to baseline across multiple sites. Determine whether client-level outcomes are further enhanced by …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Duke University, Durham, North Carolina

   Locations

   3 in total

   Run by

   Brown University

   See if you can join NCT04978168 on ClinicalTrials.gov

5. EXPANDED SCOPE for Parent Grant Entitled, "Peer Recovery Support Services for Individuals in Recovery Residences on MOUD"

   The United States is experiencing an unprecedented opioid epidemic. Medications for opioid use disorder (MOUD), such as methadone, buprenorphine, and extended-release naltrexone, are the recommended standard of care. There are, however, many barriers to MOUD initiation so that only a minority of in…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Maryland Treatment Centers, Baltimore, Maryland

   Run by

   Potomac Health Foundations

   See if you can join NCT06696157 on ClinicalTrials.gov

6. Brain Training for Substance Use Disorders

   Participants play games designed to train visual attention towards natural, non-drug-related scenarios. A biofeedback loop between gameplay and an electroencephalogram (EEG) system monitors game performance and guides game difficulty.

   Stage

   Not phased

   Ages

   18 to 65

   Site

   University of Minnesota - Department of Psychiatry & Behavioral Health, Minneapolis, Minnesota

   Run by

   Neurotype Inc.

   See if you can join NCT06870110 on ClinicalTrials.gov

7. Postpartum Intervention for Mothers With Opioid Use Disorders

   Opioid use disorder (OUD) is a fast-growing and devastating epidemic in the US with many mothers suffering cravings, depression, impaired interpersonal interactions and maladaptive parenting behaviors that may lead to child maltreatment and costly utilization of foster care. This interdisciplinary …

   Stage

   Not phased

   Ages

   18 to 50

   Site

   University of Michigan, Ann Arbor, Michigan

   Locations

   2 in total

   Run by

   Stony Brook University

   See if you can join NCT05614661 on ClinicalTrials.gov

8. Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis

   The opioid epidemic has become one of America's deadliest crises, surpassing car crashes, firearms, and HIV/AIDS as a leading cause of death for Americans under fifty years of age. People trying to recover from opioid-use disorder face many obstacles. Obstacles such as minor legal problems (e.g., a…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Home of New Vision, Ann Arbor, Michigan

   Locations

   2 in total

   Run by

   University of Michigan

   See if you can join NCT05665179 on ClinicalTrials.gov

9. Focused Ultrasound for the Complex Patient

   The goal of this clinical trial is to to inhibit the anterior insula (AI) with low intensity focused ultrasound (LIFU) to determine the causal role for the AI in pain processing, anxiety, and opiate cue-induced craving. The main question[s] it aims to answer are: * the safety and tolerability of LI…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Washington DC Veterans Affairs Medical Center, Washington D.C., District of Columbia

   Run by

   Washington D.C. Veterans Affairs Medical Center

   See if you can join NCT06453109 on ClinicalTrials.gov

10. Ketamine Assisted Psychotherapy for Opioid Use Disorder

    This pilot clinical trial aims to assess the preliminary efficacy of ketamine as an adjunct for a mindfulness-based intervention for opioid use disorder.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Center on Mindfulness and Integrative Health Intervention Development, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT04892251 on ClinicalTrials.gov