Opioid Use Disorder Clinical Trials in Pittsburgh, Pennsylvania

6 studies are recruiting for opioid use disorder in Pittsburgh, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

   VA-BRAVE will determine whether a 28-day long-acting injectable sub-cutaneous formulation of buprenorphine at a target dose of 300 milligrams (mg) is superior in retaining Veterans in opioid treatment and in sustaining opioid abstinence compared to the daily sublingual (under the tongue) buprenorph…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh, Pennsylvania

   Locations

   25 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT04375033 on ClinicalTrials.gov

2. Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

   This is a pilot study to evaluate the safety and efficacy of deep brain stimulation (DBS) of the nucleus accumbens (NAc) as adjunctive treatment for treatment-refractory opioid use disorder. This study will include 3 individuals with opioid use disorder and relapsing opioid use despite active parti…

   Stage

   Not phased

   Ages

   22 to 65

   Site

   AHN Allegheny General Hospital, Pittsburgh, Pennsylvania

   Run by

   Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

   See if you can join NCT04354077 on ClinicalTrials.gov

3. Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

   This study will be a 12-month prospective, genotype-blinded longitudinal observational study with current standard of clinical care. This study will enroll 100 pregnant women with OUD at UPMC Hospitals with its high volumes. Because of the observational nature of the study, the anticipated dropout …

   Stage

   Not phased

   Ages

   18 and older

   Site

   UPMC Magee-Womens Hospital, Pittsburgh, Pennsylvania

   Run by

   Ilana Hull

   See if you can join NCT05942313 on ClinicalTrials.gov

4. Machine-Learning Prediction and Reducing Overdoses With EHR Nudges

   The goal of this cluster randomized clinical trial is to test a clinician-targeted behavioral nudge intervention in the Electronic Health Record (EHR) for patients who are identified by a machine-learning based risk prediction model as having an elevated risk for an opioid overdose. The clinical tr…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06806163 on ClinicalTrials.gov

5. Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention

   The purpose of the study is to develop an acceptable, feasible, and effective peer-led bundle of health resilience and promotion services to be delivered in the hospital setting, called the THRIVE intervention. The main question it aims to answer is: Will participants receiving the THRIVE intervent…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UPMC Presbyterian-Montefiore Hospital, Pittsburgh, Pennsylvania

   Locations

   3 in total

   Run by

   University of Pennsylvania

   See if you can join NCT06843213 on ClinicalTrials.gov

6. Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

   The objective of this study is to better understand the comprehensive integration of both clinical and genetic factors that will help to identify mothers who could be at an increased risk of poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).

   Stage

   Not phased

   Ages

   18 and older

   Site

   UPMC Children's Hospital, Pittsburgh, Pennsylvania

   Run by

   Senthil Sadhasivam

   See if you can join NCT03923374 on ClinicalTrials.gov