Opioid Use Disorder Clinical Trials in New Haven, Connecticut

10 studies are recruiting for opioid use disorder in New Haven, Connecticut right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. OMAR Opioid Use Disorder

   The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Connecticut Mental Health Center, Clinical Neuroscience Research Unit, New Haven, Connecticut

   Run by

   Yale University

   See if you can join NCT05683184 on ClinicalTrials.gov

2. Combined THC and CBD for OUD and Chronic Pain

   The primary objective of this phase 2 study is to investigate the therapeutic potential of orally administered combined delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in relieving both pain and cue-induced opioid craving in people with co-occurring opioid use disorder (OUD) and chronic pa…

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   Connecticut Mental Health Center, New Haven, Connecticut

   Run by

   Yale University

   See if you can join NCT06544291 on ClinicalTrials.gov

3. Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

   This study will examine the synaptotrophic effects of psilocybin among medically healthy, detoxified OUD subjects. Eligible OUD participants will undergo pre- and post- psilocybin administration PET scans with the [11C]-UCB-J radiotracer while inpatient.

   Stage

   Phase 1

   Ages

   25 to 55

   Site

   Yale University, New Haven, Connecticut

   Run by

   Yale University

   See if you can join NCT06160284 on ClinicalTrials.gov

4. Opioid Use Disorder and Pain

   The goal of this observational study is to characterize the brain processes of pain avoidance learning dysfunctions in individuals with opioid use disorder (OUD). The main questions it aims to answer are: Compared with healthy controls, do those with OUD exhibit impaired avoidance learning in respo…

   Stage

   Not phased

   Ages

   21 to 60

   Site

   Connecticut Mental Health Center, S105, New Haven, Connecticut

   Run by

   Yale University

   See if you can join NCT06800703 on ClinicalTrials.gov

5. Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

   The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention, Executive Functioning, Memory, and Information Processing) aimed at enh…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   APT Foundation, New Haven, Connecticut

   Run by

   University of Connecticut

   See if you can join NCT05669534 on ClinicalTrials.gov

6. Adaptive Decision Support for Addiction Treatment Master

   This study refines and optimizes the EMBED* clinical decision support (CDS; see NCT03658642) to increase number of ED physicians following standard of care for the administration of buprenorphine to appropriate patients with opioid use disorder. This study does not have open enrollment. Investigato…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Yale New Haven Hospital- St. Raphael, New Haven, Connecticut

   Locations

   3 in total

   Run by

   Yale University

   See if you can join NCT06799117 on ClinicalTrials.gov

7. Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

   The purpose of this 2-site (CT, AL) study is to test innovative interventions to reduce stigma and improve the pre-exposure prophylaxis (PrEP) and opioid use disorder (OUD) care continua in women involved in the criminal justice system (WICJ). This study evaluates a newly validated PrEP decision ai…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   Yale University, New Haven, Connecticut

   Locations

   2 in total

   Run by

   Yale University

   See if you can join NCT05547048 on ClinicalTrials.gov

8. Longitudinal Neural Fingerprinting of Opioid-use Trajectories

   This project aims to collect a densely sampled neuroimaging dataset among individuals receiving medications for opioid use disorder (MOUD). MOUD is multiphasic, comprised of medication induction, stabilization, ongoing treatment, and eventual dis-continuation phases. However, with a few small excep…

   Stage

   Not phased

   Ages

   18 to 50

   Site

   MRRC at The Anlyan Center, New Haven, Connecticut

   Run by

   Yale University

   See if you can join NCT06207162 on ClinicalTrials.gov

9. Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

   The aim of the present study is to assess the availability of cannabinoid receptors (CB1R) in the human brain. CB1R are present in everyone's brain, regardless of whether or not someone has used cannabis. The investigators will image brain cannabinoid receptors using Positron Emission Tomography (P…

   Stage

   Not phased

   Ages

   18 to 55

   Site

   Connecticut Mental Health Center, Clinical Neuroscience Research Unit, New Haven, Connecticut

   Run by

   Yale University

   See if you can join NCT01730781 on ClinicalTrials.gov

10. Expanding Medication-Assisted Therapies in Central Asia

    Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more eff…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Yale University, New Haven, Connecticut

    Locations

    4 in total

    Run by

    Yale University

    See if you can join NCT05579470 on ClinicalTrials.gov