Hypertension Clinical Trials

143 studies are recruiting for hypertension in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 5

1. Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)

   This exploratory, first-in-man, phase 0 study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 ([18F]FNP-59) to image the adrenal gland in healthy normal subjects. The researchers believe that [18F]FNP-59 would greatly improve the imaging characterist…

   Stage

   EARLY_Phase 1

   Ages

   18 and older

   Site

   University of Michigan, Ann Arbor, Michigan

   Run by

   Benjamin Viglianti

   See if you can join NCT04532489 on ClinicalTrials.gov

2. Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)

   This study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 ([18F]FNP-59) to image the adrenal gland. Some participants are healthy normal subjects but have undergone interventions to manipulate hormones while other participants have known adrenal pat…

   Stage

   EARLY_Phase 1

   Ages

   18 and older

   Site

   University of Michigan, Ann Arbor, Michigan

   Locations

   2 in total

   Run by

   Benjamin Viglianti

   See if you can join NCT04546126 on ClinicalTrials.gov

3. Partners in Control, Phase II: Using Remote Monitoring Technology With Community Health Workers to Support Hypertension Management for Latinx Patients

   This study seeks to evaluate the impact of a remote patient monitoring (RPM)-specific tech-enabled community health worker workforce on the use of RPM for the management of hypertension among Latinx patients. This study is a step-wedge randomized controlled trial that aims to assess the effectivene…

   Stage

   Not phased

   Ages

   18 and older

   Site

   NYU Langone Health, New York, New York

   Run by

   NYU Langone Health

   See if you can join NCT06730230 on ClinicalTrials.gov

4. Preventing Cognitive Decline by Reducing BP Target Trial

   The PCOT study is a multi-site randomized trial of patients 70 years or older with high BP. The main goal of the study Preventing Cognitive Decline by Reducing BP Target Trial (PCOT) is to conduct a large pragmatic clinical trial (PCT) to test the hypothesis that patients who receive care with a co…

   Stage

   Not phased

   Ages

   70 and older

   Site

   UT Southwestern Medical Center, Dallas, Texas

   Run by

   University of Texas Southwestern Medical Center

   See if you can join NCT05106036 on ClinicalTrials.gov

5. How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes

   The goal of this clinical trial is to is to determine the effects of baked potato with the skin (BP) + nutrition education focused on adherence for a Mediterranean Dietary Pattern (MEDNE) on glycemic control, cardiometabolic health, and dietary quality in individuals with pre-diabetes from differen…

   Stage

   Not phased

   Ages

   45 to 80

   Site

   University of Nevada Las Vegas, Las Vegas, Nevada

   Locations

   2 in total

   Run by

   University of Nevada, Las Vegas

   See if you can join NCT06817252 on ClinicalTrials.gov

6. Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

   Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them with hospital- and community-based education, navigation and self-man…

   Stage

   Not phased

   Ages

   18 to 70

   Site

   University of Chicago Medical Center, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT06397456 on ClinicalTrials.gov

7. Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors

   Hypertension and obesity are both major risk factors for cardiovascular disease (CVD), a leading cause of death for Black women in the United States. The investigators propose examining the feasibility and acceptability of the 12-week RN-CHeFRx (Real Nourishment and Cooking Healthy Food is Rx) inte…

   Stage

   Not phased

   Ages

   18 to 99

   Site

   University of Illinois Chicago, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT06504914 on ClinicalTrials.gov

8. Gut Microbiota in Metabolic Surgery

   Metabolic surgery is an emerging option to treat obesity-related metabolic diseases (e.g., type 2 diabetes) and prevent cardiovascular disease (CVD). Metabolic surgery can profoundly alter the gut microbiota; meanwhile, gut microbiota may affect surgical outcomes. Longitudinal studies that examined…

   Stage

   Not phased

   Ages

   21 to 65

   Site

   Vanderbilt_University MC, Nashville, Tennessee

   Run by

   Vanderbilt University Medical Center

   See if you can join NCT05000996 on ClinicalTrials.gov

9. Healthy Living Anson Study

   The goal of this randomized delayed control intervention research study is to see if participants who receive education and healthy prepared meals improve the quality of their diet compared to participants who receive only physical activity education and coaching.

   Stage

   Not phased

   Ages

   18 to 99

   Site

   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT07126587 on ClinicalTrials.gov

10. Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults

    The prevalence of overweight and obesity remains epidemic in the United States, with some of the highest rates seen in older adults. While this phenomenon is certainly multifactorial, a good deal of evidence suggests that insufficient physical activity (PA) contributes significantly. Pilot data rec…

    Stage

    Not phased

    Ages

    20 and older

    Site

    Kennesaw State Universityh, Kennesaw, Georgia

    Run by

    Kennesaw State University

    See if you can join NCT07221279 on ClinicalTrials.gov

11. bpMedManage: Digital Technology to Support Adherence to Hypertension Medications

    The purpose of the bpMedManage study is to rigorously test the efficacy of a smartphone technology to help improve high blood pressure medication adherence among older adults with mild cognitive impairment (MCI) in a 16-week randomized controlled trial. A total of 100 older adults will be recruited…

    Stage

    Not phased

    Ages

    60 and older

    Site

    University of Arizona, Tucson, Arizona

    Locations

    2 in total

    Run by

    University of Arizona

    See if you can join NCT06307574 on ClinicalTrials.gov

12. SMBP Study: Improving High Blood Pressure in Older Adults With Multiple Chronic Diseases

    Nearly half of adults in the United States (47 percent, or 116 million) have hypertension, also known as high blood pressure (BP). Uncontrolled high BP can be devasting as it can lead to stroke, heart attack and kidney failure, as well as other numerous health conditions. Hypertension can be contro…

    Stage

    Not phased

    Ages

    65 and older

    Site

    University of Iowa Health Care, Iowa City, Iowa

    Locations

    2 in total

    Run by

    Korey Kennelty

    See if you can join NCT06932029 on ClinicalTrials.gov

13. Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment

    High blood pressure (BP) or hypertension (HTN) affects over 100 million individuals in the US, increasing the risk of adverse outcomes, including stroke, myocardial infarction (MI), and chronic kidney disease (CKD). Effective therapies include non-pharmacologic approaches and multiple medication cl…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Boston Healthcare for the Homeless (BHCHP), Boston, Massachusetts

    Locations

    7 in total

    Run by

    Boston Medical Center

    See if you can join NCT06948838 on ClinicalTrials.gov

14. A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities

    The LINKED- HEARTS Program is a multi-level project that intervenes at the practice level by linking home blood pressure monitoring (HBPM) with a telemonitoring platform (Sphygmo). The program incorporates team-based care by including community health workers (CHWs) and pharmacists to improve the o…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Unity Health Care, Washington D.C., District of Columbia

    Locations

    3 in total

    Run by

    Johns Hopkins University

    See if you can join NCT05321368 on ClinicalTrials.gov

15. Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

    Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having …

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06055036 on ClinicalTrials.gov

16. Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

    Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of this protein results in glucosuria and lower serum blood sugar. The SGLT2i medications were initially approved to treat type 2 diabetes (T2…

    Stage

    EARLY_Phase 1

    Ages

    60 and older

    Site

    University of Minnesota, Minneapolis, Minnesota

    Run by

    University of Minnesota

    See if you can join NCT06507657 on ClinicalTrials.gov

17. Team Lifestyle Immersion Hypertension Control Project

    This project is focuses on reducing the risk and progression of hypertension among a population that records high incidence of hypertension and other chronic ailments such as heart disease, diabetes, kidney failure, and obesity, with similar control measures. Several clinical trials over the last f…

    Stage

    Not phased

    Ages

    30 to 80

    Site

    Meharry Medical College, Nashville, Tennessee

    Run by

    Meharry Medical College

    See if you can join NCT07201948 on ClinicalTrials.gov

18. : Vascular Function in Health and Disease

    Many control mechanisms exist which successfully match the supply of blood with the metabolic demand of various tissues under wide-ranging conditions. One primary regulator of vasomotion and thus perfusion to the muscle tissue is the host of chemical factors originating from the vascular endotheliu…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    George E Wahlen VA Medical Center, Salt Lake City, Utah

    Run by

    Russell Richardson

    See if you can join NCT02966665 on ClinicalTrials.gov

19. AM vs PM Exercise Training

    The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with…

    Stage

    Not phased

    Ages

    55 to 80

    Site

    Michigan State University, East Lansing, Michigan

    Run by

    Michigan State University

    See if you can join NCT06042439 on ClinicalTrials.gov

20. BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement

    The investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health. The goal of this study is to compare two new ways of lowering blood pressure. The first way is to help people check their b…

    Stage

    Not phased

    Ages

    35 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT07091851 on ClinicalTrials.gov

21. Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension

    Obesity is a global health concern that is associated with high blood pressure and an increased risk for developing cardiovascular disease. The purpose of this study is to find out if the investigational drug angiotensin-(1-7) can improve cardiovascular health in people with obesity and high blood …

    Stage

    EARLY_Phase 1

    Ages

    18 to 65

    Site

    Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania

    Run by

    Milton S. Hershey Medical Center

    See if you can join NCT06482853 on ClinicalTrials.gov

22. Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study

    The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes. Duke will perform a secondary analysis of the data collected as part …

    Stage

    Not phased

    Ages

    12 to 17

    Site

    Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida

    Run by

    Duke University

    See if you can join NCT06596265 on ClinicalTrials.gov

23. Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices

    (1) To compare cuff-less wrist wearable radial artery blood pressure measurements utilizing ViTrack(developed by Dynocardia) to the cuff based commercially available blood pressure device, in healthy volunteers with normal or high blood pressure.

    Stage

    Not phased

    Ages

    18 to 90

    Site

    Dynocardia Inc, Newton, Massachusetts

    Run by

    Dynocardia, Inc

    See if you can join NCT04835857 on ClinicalTrials.gov

24. Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study

    The Fit2Play prospective cohort study examines the effects of a park-based youth physical activity afterschool program on youth participant fitness and mental health outcomes. Duke will perform a secondary analysis of the data collected as part of the Fit2Play prospective cohort study run by Miami-…

    Stage

    Not phased

    Ages

    6 to 14

    Site

    Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida

    Run by

    Duke University

    See if you can join NCT06595251 on ClinicalTrials.gov

25. Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study

    The Active Older Adults prospective cohort study examines the effects of a park-based fitness program on cardiovascular fitness outcomes for older adults (aged 50 years and older). Duke will perform a secondary analysis of the data collected as part of the Active Older Adults prospective cohort stu…

    Stage

    Not phased

    Ages

    50 to 95

    Site

    Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida

    Run by

    Duke University

    See if you can join NCT06604650 on ClinicalTrials.gov