Hypertension Clinical Trials in Chicago, Illinois

20 studies are recruiting for hypertension in Chicago, Illinois right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

   The purpose of this study is to evaluate whether zilebesiran versus placebo reduces the risk of cardiovascular (CV) death, nonfatal myocardial infarction (MI), nonfatal stroke, or heart failure (HF) events. This is an event-driven study that will continue until the targeted number of positively adj…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Clinical Trial Site, Chicago, Illinois

   Locations

   1153 in total

   Run by

   Alnylam Pharmaceuticals

   See if you can join NCT07181109 on ClinicalTrials.gov

2. EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

   This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these conditions and do not have a history of heart failure. The purpose of this study is to find out if a medicine called vicadrostat, when taken with empaglif…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Cedar Crosse Research Center, Chicago, Illinois

   Locations

   1143 in total

   Run by

   Boehringer Ingelheim

   See if you can join NCT07064473 on ClinicalTrials.gov

3. Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension

   The purpose of this study is to evaluate the blood pressure-lowering effect of tonlamarsen in adult participants who were recently hospitalized and concurrently experienced an episode of acute severe hypertension.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Eagle Clinical Research, Chicago, Illinois

   Locations

   11 in total

   Run by

   Kardigan, Inc.

   See if you can join NCT07511361 on ClinicalTrials.gov

4. MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors

   Inflammation and stressors can interfere with the function of the lining of blood vessels and insulin activity, therefore, investigators are aiming to see how the Grape seed Extract (GSE) called MegaNatural BP can help with limiting the effects of these factors. This research will study the effects…

   Stage

   Not phased

   Ages

   40 to 60

   Site

   Clinical Nutrition Research Center, Chicago, Illinois

   Run by

   Clinical Nutrition Research Center, Illinois Institute of Technology

   See if you can join NCT06555952 on ClinicalTrials.gov

5. BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

   A prospective, multinational, randomized, double-blind, clinical trial evaluating the safety and effectiveness of a novel atrioventricular interval modulation (AVIM) algorithm downloaded into a dual-chamber Medtronic Astra/Azure pacemaker.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Chicago, Chicago, Illinois

   Locations

   131 in total

   Run by

   Orchestra BioMed, Inc

   See if you can join NCT06059638 on ClinicalTrials.gov

6. Preventative Screening and Health Coaching in a Food Insecure Population

   The goal of this longitudinal study is to investigate the role of virtual health coaching on mitigation of cardiometabolic disease risk in an underserved, food insecure population. The main questions it aims to answer are: * Does longitudinal, individualized health coaching directed at lifestyle mo…

   Stage

   Not phased

   Ages

   40 to 75

   Site

   Rush University Medical Center, Chicago, Illinois

   Run by

   Rush University Medical Center

   See if you can join NCT06907524 on ClinicalTrials.gov

7. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

   The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

   Stage

   Not phased

   Ages

   0 to 20

   Site

   Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois

   Locations

   52 in total

   Run by

   Duke University

   See if you can join NCT04278404 on ClinicalTrials.gov

8. Study of the Progression of Chronic Cardiovascular Conditions

   This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Prolaio, Chicago, Illinois

   Run by

   Prolaio

   See if you can join NCT07420907 on ClinicalTrials.gov

9. Optimizing Sustainable Cuff Access and Training Pathways for Self-Measured Blood Pressure Monitoring in Primary Care

   The goal of this study is to identify what cuff delivery and BP log return modality most effectively achieve successful delivery of a self-measured blood pressure (SMBP) intervention in routine care, among adult primary care patients with uncontrolled hypertension?

   Stage

   Not phased

   Ages

   18 and older

   Site

   Advocate Medical Group Chicago (Southeast), Chicago, Illinois

   Locations

   6 in total

   Run by

   Wake Forest University Health Sciences

   See if you can join NCT07693699 on ClinicalTrials.gov

10. A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

    The study will be a multi-center, randomized clinical trial to evaluate the safety and efficacy of using the Zona Plus handgrip therapy device compared to the use of an auditory relaxation therapy for treatment of high blood pressure and hypertension in subjects who are not currently taking antihyp…

    Stage

    Not phased

    Ages

    22 and older

    Site

    Cedar Crosse Research Center, Chicago, Illinois

    Locations

    10 in total

    Run by

    Zona Health, Inc

    See if you can join NCT06843577 on ClinicalTrials.gov

11. FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

    The goal of this clinical trial is to treat both hypertension and obesity in adults using a food is medicine framework. Participants will be randomized 1:1 to FIM+DASH or usual-care control. The 24-week trial includes a 12-week FIM+DASH intervention followed by a 12-week maintenance period and leve…

    Stage

    Phase 2

    Ages

    Any age

    Site

    Mile Square Health Center - South Shore, Chicago, Illinois

    Locations

    4 in total

    Run by

    University of Illinois at Chicago

    See if you can join NCT07332741 on ClinicalTrials.gov

12. The REACH-OUT Trial

    Test the effectiveness of a technology-enabled strategy to optimize blood pressure among reproductive-aged women with hypertension receiving care in Federally Qualified Health Centers.

    Stage

    Not phased

    Ages

    18 to 44

    Site

    Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT07540143 on ClinicalTrials.gov

13. E3 Hypertension - A Team-based, Multidisciplinary Model in Addressing Barriers to Hypertension Control

    This study aims to compare a multidisciplinary clinical hypertension and social needs intervention to enhanced standard of care for hypertension management in primary care clinics with regards to hypertension control outcomes.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rush University Medical Center, Chicago, Illinois

    Run by

    Rush University Medical Center

    See if you can join NCT06899750 on ClinicalTrials.gov

14. Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients

    The diagnosis of hypertensive disease during pregnancy is predicated on strict blood pressure thresholds: 140/90 on at least two occasions measured four hours apart for both gestational hypertension and preeclampsia. An improvement in diagnostic accuracy of even 5mm Hg would be significant, as refl…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Prentice Women's Hospital, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT06466161 on ClinicalTrials.gov

15. Mobilizing Community Hypertension Access Pilot

    The Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted community settings on the West and South Sides of Chicago. Adults with uncon…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rush University Medical Center, Chicago, Illinois

    Run by

    Rush University Medical Center

    See if you can join NCT07547345 on ClinicalTrials.gov

16. Community-based Approach to Lowering Stress Through Mindfulness

    The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are: * Does participation in a culturally a…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Salvation Army Ray and Joan Kroc Corps Community Center Chicago, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT06987799 on ClinicalTrials.gov

17. Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

    Durable left ventricular assist devices (dLVAD) have been increasingly utilized since the mid to late 1990s, with an uptick of utility starting in 2010 following expanded indications for therapy to not only include a bridge to transplantation strategy, but also for those individuals who suffer from…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    University of Chicago, Chicago, Illinois

    Locations

    7 in total

    Run by

    International Consortium of Circulatory Assist Clinicians

    See if you can join NCT06039176 on ClinicalTrials.gov

18. Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

    Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them with hospital- and community-based education, navigation and self-man…

    Stage

    Not phased

    Ages

    18 to 70

    Site

    University of Chicago Medical Center, Chicago, Illinois

    Run by

    University of Chicago

    See if you can join NCT06397456 on ClinicalTrials.gov

19. Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors

    Hypertension and obesity are both major risk factors for cardiovascular disease (CVD), a leading cause of death for Black women in the United States. The investigators propose examining the feasibility and acceptability of the 12-week RN-CHeFRx (Real Nourishment and Cooking Healthy Food is Rx) inte…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    University of Illinois Chicago, Chicago, Illinois

    Run by

    University of Illinois at Chicago

    See if you can join NCT06504914 on ClinicalTrials.gov

20. Interactive Computer-adaptive Chronic Kidney Disease Education Program

    The goal of this pilot clinical trial is to evaluate a culturally tailored computerized education program in hospitalized African-American patients with advanced chronic kidney disease (CKD). The main question it aims to answer are: does computerized adaptive education (CAE) increase patients' know…

    Stage

    Not phased

    Ages

    18 to 70

    Site

    University of Chicago Medical Center, Chicago, Illinois

    Run by

    University of Chicago

    See if you can join NCT06364358 on ClinicalTrials.gov