Hypertension Clinical Trials in Boston, Massachusetts

14 studies are recruiting for hypertension in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

   A prospective, multinational, randomized, double-blind, clinical trial evaluating the safety and effectiveness of a novel atrioventricular interval modulation (AVIM) algorithm downloaded into a dual-chamber Medtronic Astra/Azure pacemaker.

   Stage

   Not phased

   Ages

   18 and older

   Site

   St. Elizabeth's Medical Center, Boston, Massachusetts

   Locations

   131 in total

   Run by

   Orchestra BioMed, Inc

   See if you can join NCT06059638 on ClinicalTrials.gov

2. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

   The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

   Stage

   Not phased

   Ages

   0 to 20

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Locations

   52 in total

   Run by

   Duke University

   See if you can join NCT04278404 on ClinicalTrials.gov

3. Groceries for Residents of Southeastern USA to Stop Hypertension

   GoFreshSE is a randomized control trial, testing the effects of a home-delivered, dietitian-assisted, DASH-patterned grocery intervention on blood pressure in adults with high blood pressure in Florida, Georgia, and Tennessee.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Beth Israel Deaconess Medical Center, Boston, Massachusetts

   Run by

   Beth Israel Deaconess Medical Center

   See if you can join NCT06891911 on ClinicalTrials.gov

4. Global Paradise System US Post Approval Study

   The objective of the Global Paradise® System US Post Approval Study (US GPS) is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This system is comprised of a…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   43 in total

   Run by

   ReCor Medical, Inc.

   See if you can join NCT06297291 on ClinicalTrials.gov

5. Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

   The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the >30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care enga…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT06557005 on ClinicalTrials.gov

6. Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia

   The goal of this clinical trial is to determine if the medication eplerenone yields greater improvements in coronary microvascular function than chlorthalidone in women who experienced preeclampsia during pregnancy and subsequently developed chronic hypertension. The main Aims are: * To test the hy…

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Massachusetts General Hospital

   See if you can join NCT07238400 on ClinicalTrials.gov

7. SPYRAL GEMINI Pilot Study

   The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure reduction when studied in an uncontrolled hypertensive population with and without high cardiovascular risk.

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Beth Israel Deaconess Medical Center, Boston, Massachusetts

   Locations

   18 in total

   Run by

   Medtronic Vascular

   See if you can join NCT06907147 on ClinicalTrials.gov

8. Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

   This observational study will assess the long-term effectiveness of the RDN procedure for lowering blood pressure in Medicare patients with uncontrolled hypertension. This research will be conducted using de-identified electronic health records (EHR) and administrative health insurance claims data.…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Beth Israel Deaconess Medical Center, Boston, Massachusetts

   Run by

   Medtronic Vascular

   See if you can join NCT07174622 on ClinicalTrials.gov

9. Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

   The investigators' goal is to show that in hypertensive men and women with left ventricular hypertrophy (LVH) treatment with a mineralocorticoid receptor (MR) antagonist, versus a thiazide-like diuretic, will improve coronary microvascular function and cardiac efficiency, which will associate with …

   Stage

   Phase 4

   Ages

   18 to 75

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT05593055 on ClinicalTrials.gov

10. Remote Fetal Monitoring in High Risk Pregnancies

    Antenatal nonstress tests (NSTs) are performed to assess fetal health and are used as a cost-effective test that can be widely administered. However, an NST is operator-dependent due to the nature of Doppler ultrasound and is primarily performed in a clinic and hospital setting. The ability to cond…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Beth Israel Deaconess Medical Center, Boston, Massachusetts

    Run by

    Beth Israel Deaconess Medical Center

    See if you can join NCT06822439 on ClinicalTrials.gov

11. Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment

    High blood pressure (BP) or hypertension (HTN) affects over 100 million individuals in the US, increasing the risk of adverse outcomes, including stroke, myocardial infarction (MI), and chronic kidney disease (CKD). Effective therapies include non-pharmacologic approaches and multiple medication cl…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Boston Healthcare for the Homeless (BHCHP), Boston, Massachusetts

    Locations

    7 in total

    Run by

    Boston Medical Center

    See if you can join NCT06948838 on ClinicalTrials.gov

12. BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement

    The investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health. The goal of this study is to compare two new ways of lowering blood pressure. The first way is to help people check their b…

    Stage

    Not phased

    Ages

    35 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT07091851 on ClinicalTrials.gov

13. Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension

    The goal of this study is to determine if 12 weeks of cycling exercise training at home will improve three parameters: 1) blood pressure, 2) cognition, and 3) walking ability among persons with multiple sclerosis who have high blood pressure, when compared to a group that engages in a 12-week home-…

    Stage

    Not phased

    Ages

    18 and older

    Site

    UMass Boston, Boston, Massachusetts

    Run by

    University of Massachusetts, Boston

    See if you can join NCT06554340 on ClinicalTrials.gov

14. Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

    This research study aims to learn more about the impact the hormone aldosterone on the heart. Primary aldosteronism is a condition where the body's adrenal glands make too much of the hormone aldosterone, which can cause high blood pressure and increase the risk of heart and kidney disease. Treatme…

    Stage

    Phase 4

    Ages

    18 to 85

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT05030545 on ClinicalTrials.gov