Hypertension Clinical Trials in Philadelphia, Pennsylvania

6 studies are recruiting for hypertension in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

   The purpose of this study is to evaluate whether zilebesiran versus placebo reduces the risk of cardiovascular (CV) death, nonfatal myocardial infarction (MI), nonfatal stroke, or heart failure (HF) events. This is an event-driven study that will continue until the targeted number of positively adj…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Clinical Trial Site, Philadelphia, Pennsylvania

   Locations

   1153 in total

   Run by

   Alnylam Pharmaceuticals

   See if you can join NCT07181109 on ClinicalTrials.gov

2. EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

   This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these conditions and do not have a history of heart failure. The purpose of this study is to find out if a medicine called vicadrostat, when taken with empaglif…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Thomas Jefferson University, Philadelphia, Pennsylvania

   Locations

   1143 in total

   Run by

   Boehringer Ingelheim

   See if you can join NCT07064473 on ClinicalTrials.gov

3. THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

   The primary objective of the THRIVE Pivotal study is to demonstrate the adjunctive effectiveness and the safety of the TIVUS system in: 1. subjects with uncontrolled hypertension (HTN) receiving 0 - 2 anti-hypertensive drugs of different classes in whom the anti-hypertensive medications will be sto…

   Stage

   Not phased

   Ages

   22 to 75

   Site

   Penn Medicine, Philadelphia, Pennsylvania

   Locations

   50 in total

   Run by

   SoniVie Inc.

   See if you can join NCT06559891 on ClinicalTrials.gov

4. Sleep Promotion and Pediatric Hypertension

   Determine the effectiveness and feasibility of a mobile health sleep extension approach in the pediatric nephrology setting, to increase sleep duration and reduce systolic and diastolic blood pressure.

   Stage

   Not phased

   Ages

   13 to 18

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT06642246 on ClinicalTrials.gov

5. BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

   A prospective, multinational, randomized, double-blind, clinical trial evaluating the safety and effectiveness of a novel atrioventricular interval modulation (AVIM) algorithm downloaded into a dual-chamber Medtronic Astra/Azure pacemaker.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   131 in total

   Run by

   Orchestra BioMed, Inc

   See if you can join NCT06059638 on ClinicalTrials.gov

6. Penn Medicine Healthy Heart

   To leverage access to patients across the primary care network, EPIC tools for identifying eligible patients, and the Way to Health platform to launch and enroll a program that will be evaluated in a clinical trial that is focused on changing patient behavior and powered to detect differences in im…

   Stage

   Not phased

   Ages

   35 to 80

   Site

   Penn Medicine, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT06062394 on ClinicalTrials.gov