Hypertension Clinical Trials in Birmingham, Alabama

9 studies are recruiting for hypertension in Birmingham, Alabama right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

   The purpose of this study is to evaluate whether zilebesiran versus placebo reduces the risk of cardiovascular (CV) death, nonfatal myocardial infarction (MI), nonfatal stroke, or heart failure (HF) events. This is an event-driven study that will continue until the targeted number of positively adj…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Clinical Trial Site, Birmingham, Alabama

   Locations

   1153 in total

   Run by

   Alnylam Pharmaceuticals

   See if you can join NCT07181109 on ClinicalTrials.gov

2. THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

   The primary objective of the THRIVE Pivotal study is to demonstrate the adjunctive effectiveness and the safety of the TIVUS system in: 1. subjects with uncontrolled hypertension (HTN) receiving 0 - 2 anti-hypertensive drugs of different classes in whom the anti-hypertensive medications will be sto…

   Stage

   Not phased

   Ages

   22 to 75

   Site

   Cardiology, PC, Birmingham, Alabama

   Locations

   50 in total

   Run by

   SoniVie Inc.

   See if you can join NCT06559891 on ClinicalTrials.gov

3. Therapeutic Mechanisms of Epidural Spinal Cord Stimulation

   The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions i…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05556902 on ClinicalTrials.gov

4. Early Time-Restricted Eating in Older Adults With Hypertension

   The purpose of this study is to find out how early time-restricted eating affects body rhythms and improves cardiometabolic health in older adults.

   Stage

   Not phased

   Ages

   60 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT07135505 on ClinicalTrials.gov

5. Arterial Stiffness and Blood Pressure

   Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertensio…

   Stage

   Not phased

   Ages

   60 and older

   Site

   Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama

   Locations

   3 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT06495710 on ClinicalTrials.gov

6. PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

   Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death. Natriuretic Peptides (NPs) are hormones produced by the heart which directly regulate BP by causi…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT04971720 on ClinicalTrials.gov

7. CARBON: UAB Cardiovascular Research Biobank

   The UAB Cardiovascular Research Biobank (CARBON) will be a resource that contains biological materials, such as DNA samples, in addition to health and personal information on a large number of people over time. It will be set up so that it can be used in the future as a resource for researchers und…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05067231 on ClinicalTrials.gov

8. Inspire HER: Inspiring the Heart and Emotions for Radical Health

   Poor heart health puts Black women at risk for a shorter life with more illness than people of any other non-indigenous racial group. We will refine and conduct a randomized, wait-list controlled trial of Inspire HER (a heart health lifestyle intervention for Black women that provides health educat…

   Stage

   Not phased

   Ages

   30 to 79

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06966258 on ClinicalTrials.gov

9. Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure

   In a multi-ethnic population, a genome-wide polygenic risk score (PRS) for systolic blood pressure (SBP), incorporating over one million common genetic variants, predicts blood pressure (BP) traits and the risk of adverse cardiovascular events beyond traditional risk factors. Delivering SBP PRS inf…

   Stage

   Not phased

   Ages

   18 to 55

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06962488 on ClinicalTrials.gov