Hypertension Clinical Trials

137 studies are recruiting for hypertension in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 4

1. Mobilizing Community Hypertension Access Pilot

   The Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted community settings on the West and South Sides of Chicago. Adults with uncon…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Rush University Medical Center, Chicago, Illinois

   Run by

   Rush University Medical Center

   See if you can join NCT07547345 on ClinicalTrials.gov

2. Exercise Testing After Preeclampsia

   Though cardiovascular disease (CVD) is the leading cause of mortality in women, traditional epidemiology in this area has focused on later life, when cardiometabolic risk has already exacted a cumulative toll on the vascular system. Recent data from the investigators and others has highlighted preg…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Vanderbilt University Medical Center, Nashville, Tennessee

   Run by

   Vanderbilt University Medical Center

   See if you can join NCT06741436 on ClinicalTrials.gov

3. Arterial Stiffness and Blood Pressure

   Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertensio…

   Stage

   Not phased

   Ages

   60 and older

   Site

   William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison, Wisconsin

   Locations

   3 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT06495710 on ClinicalTrials.gov

4. Community-based Approach to Lowering Stress Through Mindfulness

   The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are: * Does participation in a culturally a…

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Salvation Army Ray and Joan Kroc Corps Community Center Chicago, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT06987799 on ClinicalTrials.gov

5. The "Check, Monitor, Control Hypertension" Study is a 24-month Randomized Trial in Houston Targeting African Americans Aged 55+. It Combines Pharmacist Counseling and CHW Support to Improve Blood Pressure Control in Hypertension Management.

   The proposed study, "Check, Monitor, Control Hypertension in Older African American Adults," is a randomized clinical trial designed to improve blood pressure control among African American adults aged 55 years and older in the Greater Houston area. Hypertension disproportionately affects African A…

   Stage

   Not phased

   Ages

   55 and older

   Site

   3100 Cleburne Street, Nabrit Science Building,, Houston, Texas

   Run by

   Texas Southern University

   See if you can join NCT07413159 on ClinicalTrials.gov

6. PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

   Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death. Natriuretic Peptides (NPs) are hormones produced by the heart which directly regulate BP by causi…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT04971720 on ClinicalTrials.gov

7. Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

   The investigators' goal is to show that in hypertensive men and women with left ventricular hypertrophy (LVH) treatment with a mineralocorticoid receptor (MR) antagonist, versus a thiazide-like diuretic, will improve coronary microvascular function and cardiac efficiency, which will associate with …

   Stage

   Phase 4

   Ages

   18 to 75

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT05593055 on ClinicalTrials.gov

8. OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)

   Hypertension (HTN) has a greater impact on African Americans (AA) than any other U.S. racial group. Uncontrolled blood pressure (BP) contributes to higher rates of disability, death, and health resource use among AA. HTN is the single most influential risk factor for cardiovascular disease (CVD), a…

   Stage

   Not phased

   Ages

   50 and older

   Site

   Case Western Reserve University, Cleveland, Ohio

   Run by

   Case Western Reserve University

   See if you can join NCT05293756 on ClinicalTrials.gov

9. Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes

   People with high blood pressure and diabetes often have low levels of key nutrients as a result of not eating enough fresh fruits and vegetables. Research studies suggest that these nutrients can lower blood pressure and blood sugar. This study will investigate if providing encouragement to adopt t…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Johns Hopkins ProHealth Clinical Research Unit, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT06921356 on ClinicalTrials.gov

10. Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication

    The goal of this clinical trial is to determine the effectiveness of a novel mobile health-based habit formation intervention for increasing and maintaining adherence to anti-hypertensive (AH) medication among people living with hypertension and indicate medication nonadherence. The main questions …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Wellth Inc., Los Angeles, California

    Run by

    Chad Stecher@asu.edu

    See if you can join NCT06876233 on ClinicalTrials.gov

11. Penn Medicine Healthy Heart

    To leverage access to patients across the primary care network, EPIC tools for identifying eligible patients, and the Way to Health platform to launch and enroll a program that will be evaluated in a clinical trial that is focused on changing patient behavior and powered to detect differences in im…

    Stage

    Not phased

    Ages

    35 to 80

    Site

    Penn Medicine, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT06062394 on ClinicalTrials.gov

12. Remote Fetal Monitoring in High Risk Pregnancies

    Antenatal nonstress tests (NSTs) are performed to assess fetal health and are used as a cost-effective test that can be widely administered. However, an NST is operator-dependent due to the nature of Doppler ultrasound and is primarily performed in a clinic and hospital setting. The ability to cond…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Beth Israel Deaconess Medical Center, Boston, Massachusetts

    Run by

    Beth Israel Deaconess Medical Center

    See if you can join NCT06822439 on ClinicalTrials.gov

13. PILI 'Āina Household

    Native Hawaiians' traditional lifestyles and diets ensured the mutual health and well-being of the land and its inhabitants, which stand in stark contrast to the disproportionately high prevalence of diet-related, cardiometabolic diseases they experience today. In this project, the investigators wi…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Kula no nā Po'e Hawai'i, Honolulu, Hawaii

    Locations

    2 in total

    Run by

    University of Hawaii

    See if you can join NCT06526273 on ClinicalTrials.gov

14. 'Ai Pono Cooking Demonstrations

    Native Hawaiians' traditional lifestyles and diets ensured the mutual health and well-being of the land and its inhabitants, which stand in stark contrast to the disproportionately high prevalence of diet-related, cardiometabolic diseases they experience today. In this project, the investigators wi…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Kula no na Poe Hawaii, Honolulu, Hawaii

    Locations

    2 in total

    Run by

    University of Hawaii

    See if you can join NCT06526650 on ClinicalTrials.gov

15. Imaging the Pathogenesis of Cerebral Small Vessel Disease

    Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use s…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Kennedy Krieger Institute, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT05703386 on ClinicalTrials.gov

16. Sympathetic Mechanisms in Obesity-Crossover Design

    We will study obese hypertensive subjects in a randomized, crossover study to determine if two weeks sympathetic blockade improves endogenous glucose production. Subjects will be studied on 3 different occasions after two weeks of receiving either placebo, amlodipine (vasodilator arm) or moxonidine…

    Stage

    Phase 1

    Ages

    18 to 65

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT05312892 on ClinicalTrials.gov

17. HTN App for HTN Control and Cardiovascular Health Among African-Americans

    The purpose of this study is to test the hypertension (HTN) app-based intervention to see if it is more effective in improving uncontrolled HTN and HTN self-care among Africian-Americans from baseline to post-intervention (immediate, 3 months and 6 months post-intervention) as compared to the stand…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT06346886 on ClinicalTrials.gov

18. Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

    A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Iloperidone for the Treatment of Participants with Uncontrolled Hypertension

    Stage

    Phase 2

    Ages

    18 to 65

    Site

    Vanda Investigative Site, Tempe, Arizona

    Locations

    28 in total

    Run by

    Vanda Pharmaceuticals

    See if you can join NCT07090161 on ClinicalTrials.gov

19. Colorado Community Engagement Alliance

    The Colorado Community Engagement Alliance (CO-CEAL) is a partnership between the University of Colorado Anschutz Medical Campus, several community-based organizations, and dozens of trusted local community members. Its mission is to address disproportionate impacts on health through active communi…

    Stage

    Not phased

    Ages

    18 to 90

    Site

    University of Colorado - Anschutz Medical Campus, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT07440316 on ClinicalTrials.gov

20. Jackson Heart Study Women's Hypertension Study

    High blood pressure is a powerful risk factor for heart disease. Black women are more likely to have high blood pressure than white women or Hispanic women. Even when they are aware they have high blood pressure, many people struggle to keep their blood pressure controlled. Research shows a connect…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    University of Mississippi Medical Center, Jackson, Mississippi

    Run by

    NYU Langone Health

    See if you can join NCT06511479 on ClinicalTrials.gov

21. Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy

    The goal of this observational study is to learn if PRAT thickness is a marker of visceral obesity and its influence on donors' kidney function and blood pressure in living kidney donors. Population includes male/female, 18 years and up, living kidney donors scheduled for nephrectomy within 6 month…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Mayo Clinic, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT06886087 on ClinicalTrials.gov

22. CARBON: UAB Cardiovascular Research Biobank

    The UAB Cardiovascular Research Biobank (CARBON) will be a resource that contains biological materials, such as DNA samples, in addition to health and personal information on a large number of people over time. It will be set up so that it can be used in the future as a resource for researchers und…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT05067231 on ClinicalTrials.gov

23. Sleep and Circadian Mechanisms in Hypertension

    This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).

    Stage

    Not phased

    Ages

    25 to 64

    Site

    Oregon Health and Science University, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT05184933 on ClinicalTrials.gov

24. Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions

    The purpose of study is to evaluate whether home visit programs are an effective method for HTN and T2DM management as compared to standard of care clinic visits.

    Stage

    Not phased

    Ages

    18 to 60

    Site

    UT Southwestern Medical Center, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT05168605 on ClinicalTrials.gov

25. Blood Pressure Care for Advancing Real-World Evidence (BPCARE)

    The goal of this randomized clinical trial is to determine whether a community health worker-delivered, multi-component behavioral intervention can improve antihypertensive medication adherence and blood pressure control among adult refugees with hypertension who are prescribed antihypertensive med…

    Stage

    Not phased

    Ages

    21 and older

    Site

    Family Health Centers of San Diego, San Diego, California

    Locations

    2 in total

    Run by

    University of California, San Diego

    See if you can join NCT07398391 on ClinicalTrials.gov