Hypertension Clinical Trials

143 studies are recruiting for hypertension in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. The REACH-OUT Trial

   Test the effectiveness of a technology-enabled strategy to optimize blood pressure among reproductive-aged women with hypertension receiving care in Federally Qualified Health Centers.

   Stage

   Not phased

   Ages

   18 to 44

   Site

   Northwestern University, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT07540143 on ClinicalTrials.gov

2. E3 Hypertension - A Team-based, Multidisciplinary Model in Addressing Barriers to Hypertension Control

   This study aims to compare a multidisciplinary clinical hypertension and social needs intervention to enhanced standard of care for hypertension management in primary care clinics with regards to hypertension control outcomes.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Rush University Medical Center, Chicago, Illinois

   Run by

   Rush University Medical Center

   See if you can join NCT06899750 on ClinicalTrials.gov

3. Medication Adherence Program

   Randomized controlled trial testing the efficacy of the Supporting Tailored Adaptive change and Reinforcement for Medication Adherence Program (STAR-MAP), a health coaching approach that aims to improve antihypertensive medication adherence, blood pressure control, and quality of life. Participants…

   Stage

   Not phased

   Ages

   40 and older

   Site

   Pennington Biomedical Research Center, Baton Rouge, Louisiana

   Locations

   5 in total

   Run by

   Tulane University

   See if you can join NCT05183763 on ClinicalTrials.gov

4. 'Eat Well' Produce Prescription RCT

   This project, conducted within the Department of Veterans Affairs Healthcare System (VHA), will study how a produce prescription (PRx) program called "Eat Well" affects Veterans' health and how often they use healthcare services. About 1 in 4 Veteran households experience food insecurity (FI), whic…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Durham VA Health Care System, Durham, North Carolina

   Run by

   Institute for Medical Research, Inc.

   See if you can join NCT07534501 on ClinicalTrials.gov

5. Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women

   The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and community resource navigation intervention improves psychological well-being, addresses non-biologic drivers of health (access to healthcare, supportive services, nutrition, housing s…

   Stage

   Not phased

   Ages

   18 to 50

   Site

   Southern GA - Colquitt County, Ellenton, Georgia

   Run by

   Emory University

   See if you can join NCT07111026 on ClinicalTrials.gov

6. Treatment With Aspirin After Preeclampsia: TAP Trial

   The objective of this research project is to conduct a single-site pilot trial to assess the feasibility and effect of low-dose aspirin to augment vascular recovery in the immediate postpartum period after preeclampsia through two specific aims: 1) to pilot test the feasibility of conducting a rand…

   Stage

   Phase 4

   Ages

   18 to 55

   Site

   University of Pittsburgh Magee-Womens Hospital, Pittsburgh, Pennsylvania

   Run by

   Malamo Countouris

   See if you can join NCT06281665 on ClinicalTrials.gov

7. Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients

   The diagnosis of hypertensive disease during pregnancy is predicated on strict blood pressure thresholds: 140/90 on at least two occasions measured four hours apart for both gestational hypertension and preeclampsia. An improvement in diagnostic accuracy of even 5mm Hg would be significant, as refl…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Prentice Women's Hospital, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT06466161 on ClinicalTrials.gov

8. Metabolic Effects of Angiotensin-(1-7)

   The overall purpose of this study is to learn more about the metabolic effects of angiotensin-(1-7) in the insulin resistant state associated with obesity. Pharmacologic approaches to increase angiotensin-(1-7) levels or its actions are currently in development for treatment of metabolic-related di…

   Stage

   Phase 1

   Ages

   18 to 60

   Site

   Vanderbilt University Medical Center, Nashville, Tennessee

   Run by

   Vanderbilt University

   See if you can join NCT02646475 on ClinicalTrials.gov

9. Social Needs Screening and Chronic Diseases Study (WE CARE)

   The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful decrease in chronic disease by monitoring conditions such as hypertensi…

   Stage

   Not phased

   Ages

   Any age

   Site

   UMass Memorial Medical Center - Hahnemann Campus, Worcester, Massachusetts

   Locations

   3 in total

   Run by

   University of Massachusetts, Worcester

   See if you can join NCT06903897 on ClinicalTrials.gov

10. Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults

    CHRONICLE is a randomized trial assessing the comparative effectiveness of providing written visit information via the patient portal (NOTES) versus NOTES plus visit audio recording (AUDIO) to older adult patients with chronic diseases on quality of life and other outcomes. During the trial, the te…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dartmouth Hitchcock Clinics Manchester, Manchester, New Hampshire

    Locations

    3 in total

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT05955339 on ClinicalTrials.gov

11. Supporting VETerans With Kidney Disease Through Food As Medicine

    The goal of this pilot clinical trial is primarily learn if produce boxes improve clinical outcomes among Veterans with kidney disease and food or nutrition insecurity. Secondly, the study will capture Veterans qualitative perspectives, experience, and engagement through semi-structured interviews.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rocky Mountain Regional VA Medical Center, Aurora, Colorado

    Run by

    VA Eastern Colorado Health Care System

    See if you can join NCT07194733 on ClinicalTrials.gov

12. Telehealth and Remote Blood Pressure

    The purpose of this research study is to compare the management of chronic hypertension during pregnancy using telehealth visits with blood pressure telemonitoring and health coaching as compared to standard in person clinic visits. The study involves pregnant woman aged 18-45 who are receiving car…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Wake Forest University Health Sciences, Winston-Salem, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT07356518 on ClinicalTrials.gov

13. Mobilizing Community Hypertension Access Pilot

    The Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted community settings on the West and South Sides of Chicago. Adults with uncon…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rush University Medical Center, Chicago, Illinois

    Run by

    Rush University Medical Center

    See if you can join NCT07547345 on ClinicalTrials.gov

14. Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

    This observational study will assess the long-term effectiveness of the RDN procedure for lowering blood pressure in Medicare patients with uncontrolled hypertension. This research will be conducted using de-identified electronic health records (EHR) and administrative health insurance claims data.…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Beth Israel Deaconess Medical Center, Boston, Massachusetts

    Run by

    Medtronic Vascular

    See if you can join NCT07174622 on ClinicalTrials.gov

15. Exercise Testing After Preeclampsia

    Though cardiovascular disease (CVD) is the leading cause of mortality in women, traditional epidemiology in this area has focused on later life, when cardiometabolic risk has already exacted a cumulative toll on the vascular system. Recent data from the investigators and others has highlighted preg…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT06741436 on ClinicalTrials.gov

16. Arterial Stiffness and Blood Pressure

    Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertensio…

    Stage

    Not phased

    Ages

    60 and older

    Site

    William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison, Wisconsin

    Locations

    3 in total

    Run by

    VA Office of Research and Development

    See if you can join NCT06495710 on ClinicalTrials.gov

17. Community-based Approach to Lowering Stress Through Mindfulness

    The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are: * Does participation in a culturally a…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Salvation Army Ray and Joan Kroc Corps Community Center Chicago, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT06987799 on ClinicalTrials.gov

18. Oura Blood Pressure Profile Study

    The proposed study is designed as a prospective, single-arm, observational, non-significant risk device study to evaluate the performance of Oura's investigational Blood Pressure Profile algorithm in identifying signs of hypertension.

    Stage

    Not phased

    Ages

    22 and older

    Site

    Ouraring, San Francisco, California

    Run by

    Ouraring Inc.

    See if you can join NCT07267871 on ClinicalTrials.gov

19. The "Check, Monitor, Control Hypertension" Study is a 24-month Randomized Trial in Houston Targeting African Americans Aged 55+. It Combines Pharmacist Counseling and CHW Support to Improve Blood Pressure Control in Hypertension Management.

    The proposed study, "Check, Monitor, Control Hypertension in Older African American Adults," is a randomized clinical trial designed to improve blood pressure control among African American adults aged 55 years and older in the Greater Houston area. Hypertension disproportionately affects African A…

    Stage

    Not phased

    Ages

    55 and older

    Site

    3100 Cleburne Street, Nabrit Science Building,, Houston, Texas

    Run by

    Texas Southern University

    See if you can join NCT07413159 on ClinicalTrials.gov

20. PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

    Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death. Natriuretic Peptides (NPs) are hormones produced by the heart which directly regulate BP by causi…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT04971720 on ClinicalTrials.gov

21. Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

    The investigators' goal is to show that in hypertensive men and women with left ventricular hypertrophy (LVH) treatment with a mineralocorticoid receptor (MR) antagonist, versus a thiazide-like diuretic, will improve coronary microvascular function and cardiac efficiency, which will associate with …

    Stage

    Phase 4

    Ages

    18 to 75

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT05593055 on ClinicalTrials.gov

22. OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)

    Hypertension (HTN) has a greater impact on African Americans (AA) than any other U.S. racial group. Uncontrolled blood pressure (BP) contributes to higher rates of disability, death, and health resource use among AA. HTN is the single most influential risk factor for cardiovascular disease (CVD), a…

    Stage

    Not phased

    Ages

    50 and older

    Site

    Case Western Reserve University, Cleveland, Ohio

    Run by

    Case Western Reserve University

    See if you can join NCT05293756 on ClinicalTrials.gov

23. Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes

    People with high blood pressure and diabetes often have low levels of key nutrients as a result of not eating enough fresh fruits and vegetables. Research studies suggest that these nutrients can lower blood pressure and blood sugar. This study will investigate if providing encouragement to adopt t…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Johns Hopkins ProHealth Clinical Research Unit, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT06921356 on ClinicalTrials.gov

24. Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication

    The goal of this clinical trial is to determine the effectiveness of a novel mobile health-based habit formation intervention for increasing and maintaining adherence to anti-hypertensive (AH) medication among people living with hypertension and indicate medication nonadherence. The main questions …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Wellth Inc., Los Angeles, California

    Run by

    Chad Stecher@asu.edu

    See if you can join NCT06876233 on ClinicalTrials.gov

25. Penn Medicine Healthy Heart

    To leverage access to patients across the primary care network, EPIC tools for identifying eligible patients, and the Way to Health platform to launch and enroll a program that will be evaluated in a clinical trial that is focused on changing patient behavior and powered to detect differences in im…

    Stage

    Not phased

    Ages

    35 to 80

    Site

    Penn Medicine, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT06062394 on ClinicalTrials.gov