Hypertension Clinical Trials

137 studies are recruiting for hypertension in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. Study of the Progression of Chronic Cardiovascular Conditions

   This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Prolaio, Chicago, Illinois

   Run by

   Prolaio

   See if you can join NCT07420907 on ClinicalTrials.gov

2. Optimizing Sustainable Cuff Access and Training Pathways for Self-Measured Blood Pressure Monitoring in Primary Care

   The goal of this study is to identify what cuff delivery and BP log return modality most effectively achieve successful delivery of a self-measured blood pressure (SMBP) intervention in routine care, among adult primary care patients with uncontrolled hypertension?

   Stage

   Not phased

   Ages

   18 and older

   Site

   Advocate Medical Group Chicago (Southeast), Chicago, Illinois

   Locations

   6 in total

   Run by

   Wake Forest University Health Sciences

   See if you can join NCT07693699 on ClinicalTrials.gov

3. Therapeutic Mechanisms of Epidural Spinal Cord Stimulation

   The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions i…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05556902 on ClinicalTrials.gov

4. A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension

   A Study of CTX340 in Participants with Uncontrolled Hypertension.

   Stage

   Phase 1

   Ages

   18 to 75

   Site

   Research Site 1, Port Orange, Florida

   Locations

   2 in total

   Run by

   CRISPR Therapeutics AG

   See if you can join NCT07758634 on ClinicalTrials.gov

5. Cardiovascular Protection After Preeclampsia With Enalapril

   The purpose of this study is to learn if postpartum women are willing to be randomized to different blood pressure medicines after delivery and how that affects blood pressure in women with hypertensive disorders of pregnancy.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Women and Infants Hospital, Providence, Rhode Island

   Run by

   Women and Infants Hospital of Rhode Island

   See if you can join NCT07222852 on ClinicalTrials.gov

6. Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study

   To determine if nifedipine and enalapril will have better blood pressure control in the postpartum setting compared to nifedipine and labetalol.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cleveland Clinic, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT07363343 on ClinicalTrials.gov

7. WEAVE NM: Heart Health and Nutrition for Life

   WEAVE NM (Wide Engagement for Assessing Vaccine Equity in New Mexico) is a community-based research initiative working to improve health outcomes in underserved populations, with a current focus on hypertension and food justice. The project centers on the lived experiences of Native American, Afric…

   Stage

   Not phased

   Ages

   18 to 84

   Site

   First Nations Community HealthSource, Albuquerque, New Mexico

   Run by

   University of New Mexico

   See if you can join NCT07074145 on ClinicalTrials.gov

8. A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

   The study will be a multi-center, randomized clinical trial to evaluate the safety and efficacy of using the Zona Plus handgrip therapy device compared to the use of an auditory relaxation therapy for treatment of high blood pressure and hypertension in subjects who are not currently taking antihyp…

   Stage

   Not phased

   Ages

   22 and older

   Site

   Bayview Research Group, Valley Village, California

   Locations

   10 in total

   Run by

   Zona Health, Inc

   See if you can join NCT06843577 on ClinicalTrials.gov

9. Behavioral Interventions Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial

   This study evaluates a new digital health program that uses artificial intelligence (AI) to help patients lower their blood pressure through personalized lifestyle recommendations. The program collects information about patients' daily habits and blood pressure readings, then uses AI to suggest lif…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Diego, La Jolla, California

   Run by

   National Bureau of Economic Research, Inc.

   See if you can join NCT07725250 on ClinicalTrials.gov

10. Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension

    The goal of this clinical trial is to determine the impact of a home-delivered foods and kitchen skills program on health and nutrition in adults with high blood pressure and food insecurity. Researchers will compare Food Resources \& Kitchen Skills (FoRKS) and Enhanced Usual Care (EUC) to evaluate…

    Stage

    Not phased

    Ages

    35 to 75

    Site

    Eskenazi Health, Indianapolis, Indiana

    Run by

    Indiana University

    See if you can join NCT05856591 on ClinicalTrials.gov

11. MIND Foods and Aerobic Training in Black Adults With HTN

    The goal of this randomized controlled trial is to determine the impact of Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet and aerobic training on cognition in Black adults with high systolic blood pressure. Researchers will compare Food Delivery and Cooking PLUS Aerobic Tra…

    Stage

    Not phased

    Ages

    35 to 75

    Site

    Eskenazi Health, Indianapolis, Indiana

    Run by

    Indiana University

    See if you can join NCT06152614 on ClinicalTrials.gov

12. The RADIANCE CED Study

    The RADIANCE CED study is a prospective observational study designed to evaluate the long-term effectiveness of ultrasound renal denervation in lowering blood pressure among patients with uncontrolled hypertension. Data will be collected from electronic health records (EHRs) of Medicare-eligible pa…

    Stage

    Not phased

    Ages

    65 and older

    Site

    Henry Ford Hospital, Detroit, Michigan

    Locations

    2 in total

    Run by

    ReCor Medical, Inc.

    See if you can join NCT07231757 on ClinicalTrials.gov

13. Reach Out 2: Emergency Department-Initiated Hypertension Mobile Health Intervention Connecting Multiple Health Systems

    Emergency department visits provide an opportunity to identify people with undiagnosed, untreated, or uncontrolled high blood pressure. In Reach Out, we will test whether a mobile health intervention yields a greater reduction in blood pressure than usual care among individuals identified with high…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    Hurley Medical Center, Flint, Michigan

    Run by

    Northwestern University

    See if you can join NCT06391073 on ClinicalTrials.gov

14. Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

    The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the >30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care enga…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT06557005 on ClinicalTrials.gov

15. FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

    The goal of this clinical trial is to treat both hypertension and obesity in adults using a food is medicine framework. Participants will be randomized 1:1 to FIM+DASH or usual-care control. The 24-week trial includes a 12-week FIM+DASH intervention followed by a 12-week maintenance period and leve…

    Stage

    Phase 2

    Ages

    Any age

    Site

    Mile Square Health Center - South Shore, Chicago, Illinois

    Locations

    4 in total

    Run by

    University of Illinois at Chicago

    See if you can join NCT07332741 on ClinicalTrials.gov

16. Integrating Free-choice Marketplace, dieTitian coacHing, cultuRally Tailored messagIng to improVE Blood Pressure

    iTHRIVE intervention is a 2-arm randomized controlled trial testing the effects of digital FARMacy, personalized dietitian coaching with produce prescriptions, and home blood pressure measurement in 100 hypertensive adults living in high food priority areas in counties in Maryland.

    Stage

    Not phased

    Ages

    21 to 70

    Site

    Johns Hopkins Community Physicians, Baltimore, Maryland

    Locations

    3 in total

    Run by

    Johns Hopkins University

    See if you can join NCT07075588 on ClinicalTrials.gov

17. Early Time-Restricted Eating in Older Adults With Hypertension

    The purpose of this study is to find out how early time-restricted eating affects body rhythms and improves cardiometabolic health in older adults.

    Stage

    Not phased

    Ages

    60 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT07135505 on ClinicalTrials.gov

18. 'Eat Well' Produce Prescription RCT

    This project, conducted within the Department of Veterans Affairs Healthcare System (VHA), will study how a produce prescription (PRx) program called "Eat Well" affects Veterans' health and how often they use healthcare services. About 1 in 4 Veteran households experience food insecurity (FI), whic…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Durham VA Health Care System, Durham, North Carolina

    Run by

    Institute for Medical Research, Inc.

    See if you can join NCT07534501 on ClinicalTrials.gov

19. Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women

    The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and community resource navigation intervention improves psychological well-being, addresses non-biologic drivers of health (access to healthcare, supportive services, nutrition, housing s…

    Stage

    Not phased

    Ages

    18 to 50

    Site

    Southern GA - Colquitt County, Ellenton, Georgia

    Run by

    Emory University

    See if you can join NCT07111026 on ClinicalTrials.gov

20. Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients

    The diagnosis of hypertensive disease during pregnancy is predicated on strict blood pressure thresholds: 140/90 on at least two occasions measured four hours apart for both gestational hypertension and preeclampsia. An improvement in diagnostic accuracy of even 5mm Hg would be significant, as refl…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Prentice Women's Hospital, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT06466161 on ClinicalTrials.gov

21. Metabolic Effects of Angiotensin-(1-7)

    The overall purpose of this study is to learn more about the metabolic effects of angiotensin-(1-7) in the insulin resistant state associated with obesity. Pharmacologic approaches to increase angiotensin-(1-7) levels or its actions are currently in development for treatment of metabolic-related di…

    Stage

    Phase 1

    Ages

    18 to 60

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt University

    See if you can join NCT02646475 on ClinicalTrials.gov

22. Social Needs Screening and Chronic Diseases Study (WE CARE)

    The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful decrease in chronic disease by monitoring conditions such as hypertensi…

    Stage

    Not phased

    Ages

    Any age

    Site

    UMass Memorial Medical Center - Hahnemann Campus, Worcester, Massachusetts

    Locations

    3 in total

    Run by

    University of Massachusetts, Worcester

    See if you can join NCT06903897 on ClinicalTrials.gov

23. Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults

    CHRONICLE is a randomized trial assessing the comparative effectiveness of providing written visit information via the patient portal (NOTES) versus NOTES plus visit audio recording (AUDIO) to older adult patients with chronic diseases on quality of life and other outcomes. During the trial, the te…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dartmouth Hitchcock Clinics Manchester, Manchester, New Hampshire

    Locations

    3 in total

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT05955339 on ClinicalTrials.gov

24. Supporting VETerans With Kidney Disease Through Food As Medicine

    The goal of this pilot clinical trial is primarily learn if produce boxes improve clinical outcomes among Veterans with kidney disease and food or nutrition insecurity. Secondly, the study will capture Veterans qualitative perspectives, experience, and engagement through semi-structured interviews.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rocky Mountain Regional VA Medical Center, Aurora, Colorado

    Run by

    VA Eastern Colorado Health Care System

    See if you can join NCT07194733 on ClinicalTrials.gov

25. Telehealth and Remote Blood Pressure

    The purpose of this research study is to compare the management of chronic hypertension during pregnancy using telehealth visits with blood pressure telemonitoring and health coaching as compared to standard in person clinic visits. The study involves pregnant woman aged 18-45 who are receiving car…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Wake Forest University Health Sciences, Winston-Salem, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT07356518 on ClinicalTrials.gov