Cardiovascular Diseases Clinical Trials

125 studies are recruiting for cardiovascular diseases in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 4

1. CARBON: UAB Cardiovascular Research Biobank

   The UAB Cardiovascular Research Biobank (CARBON) will be a resource that contains biological materials, such as DNA samples, in addition to health and personal information on a large number of people over time. It will be set up so that it can be used in the future as a resource for researchers und…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05067231 on ClinicalTrials.gov

2. Sleep and Circadian Mechanisms in Hypertension

   This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).

   Stage

   Not phased

   Ages

   25 to 64

   Site

   Oregon Health and Science University, Portland, Oregon

   Run by

   Oregon Health and Science University

   See if you can join NCT05184933 on ClinicalTrials.gov

3. Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project

   The purpose of this study is to examine how the environment and neighborhood characteristics affects the health of the area residents. The study will help determine how changing neighborhood characteristics, such as green space, affect heart health, risk factors for other diseases, sense of well- b…

   Stage

   Not phased

   Ages

   30 to 70

   Site

   University of Louisville, Louisville, Kentucky

   Run by

   University of Louisville

   See if you can join NCT03670524 on ClinicalTrials.gov

4. Cardiovascular Risk Reduction for Adults With Food Insecurity Using Structured Incentives

   The overarching aim of this proposal is to test the efficacy and cost-effectiveness of CVD-FIT, a novel, multi-component intervention that includes three components: 1) monthly income supplementation; 2) weekly structured incentive for the purchase of healthy food options; and 3) evidence-based tel…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University at Buffalo, Buffalo, New York

   Run by

   State University of New York at Buffalo

   See if you can join NCT06818669 on ClinicalTrials.gov

5. Biopsy Collection and Repository Database

   Use samples procured from patients to improve understanding of molecular, cellular, and tissue-level processes produced by a variety of cardiac diseases and therapeutic interventions.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Kentucky, Lexington, Kentucky

   Run by

   Kenneth S. Campbell

   See if you can join NCT05521503 on ClinicalTrials.gov

6. The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health

   This study will examine the effect of a healthy diet containing cottonseed oil compared to healthy diets containing other commonly consumed plant oils on biomarkers of heart and metabolic health after 4 weeks.

   Stage

   Not phased

   Ages

   25 to 60

   Site

   The Pennylvania State University, University Park, Pennsylvania

   Run by

   Penn State University

   See if you can join NCT06216678 on ClinicalTrials.gov

7. Patient Care Outreach, Navigation, Technology and Support 2.0

   This is a feasibility study employing virtual patient navigation for underserved individuals who speak English, Chinese or Spanish and were diagnosed with breast cancer or cardiovascular disease to determine the extent of usability for a virtual patient navigation portal serving people in underserv…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Zuckerberg San Francisco General Hospital, San Francisco, California

   Locations

   2 in total

   Run by

   University of California, San Francisco

   See if you can join NCT06648278 on ClinicalTrials.gov

8. Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children

   This study will evaluate the effects of whole vs. nonfat milk consumption on body composition, cardiometabolic disease risk factors, and dietary quality.

   Stage

   Not phased

   Ages

   9 to 12

   Site

   New Balance Foundation Obesity Prevention Center, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT05464186 on ClinicalTrials.gov

9. CVD/PH and Voice Characteristics

   The purpose of this study is to determine the association between patient voice signal characteristics and the presence and severity of pulmonary hypertension in patients referred for elective clinically indicated echocardiography for at Mayo Clinic MN.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT07311044 on ClinicalTrials.gov

10. Inspire HER: Inspiring the Heart and Emotions for Radical Health

    Poor heart health puts Black women at risk for a shorter life with more illness than people of any other non-indigenous racial group. We will refine and conduct a randomized, wait-list controlled trial of Inspire HER (a heart health lifestyle intervention for Black women that provides health educat…

    Stage

    Not phased

    Ages

    30 to 79

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT06966258 on ClinicalTrials.gov

11. Vascular Lab Resource (VLR) Biorepository

    This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases. The purpose of this initiative is to develop an enduring tool to allow for collaborative research between clinicians at Cleveland Clinic Main Campus …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cleveland Clinic, Cleveland, Ohio

    Run by

    The Cleveland Clinic

    See if you can join NCT05628948 on ClinicalTrials.gov

12. Biobank Cardiac Surgery

    Treatment strategies for cardiac surgery patients have been evolving significantly for the last decade. While clinical outcomes have been improving, there are still significant areas unexplored in these patients. Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels p…

    Stage

    Not phased

    Ages

    Any age

    Site

    The University of Chicago, Hyde Park, Illinois

    Run by

    University of Chicago

    See if you can join NCT06747806 on ClinicalTrials.gov

13. Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

    This is a randomized placebo-controlled study in treated and suppressed HIV-infected individuals aged ≥40 years with either known CVD or 1 CVD risk factor to study the effect of Bempedoic acid (BA) on safety, arterial inflammation as assessed by FDG-PET/CT, lipids, inflammation, immune activation, …

    Stage

    Phase 2

    Ages

    40 and older

    Site

    UCLA Center for Clinical AIDS Research and Education (CARE), Los Angeles, California

    Locations

    3 in total

    Run by

    Priscilla Hsue, MD

    See if you can join NCT05488431 on ClinicalTrials.gov

14. Omega-3D: Omega-3 for Diet-Driven Health Disparities

    The goal of this clinical trial is to learn whether omega-3 fatty acid supplementation can reduce inflammation-related biomarkers and improve cardiovascular health in healthy adult volunteers with different genetic backgrounds. The main questions it aims to answer are: Does the response to omega-3 …

    Stage

    Phase 2

    Ages

    18 to 64

    Site

    Arizona Cancer Center, Tucson, Arizona

    Locations

    2 in total

    Run by

    University of Arizona

    See if you can join NCT07078344 on ClinicalTrials.gov

15. Designing and Assessing a Women Only Cardiac Rehabilitation (CARE) Program

    The purpose of this randomized controlled study is to investigate the effect(s) of a pilot women-only cardiac rehabilitation (CR) program. The study team will be testing the effectiveness, compliance and enjoyment of this women's only cardiac rehabilitation (CR) program by comparing outcomes to tho…

    Stage

    Not phased

    Ages

    40 to 80

    Site

    University of Michigan, Ann Arbor, Michigan

    Run by

    University of Michigan

    See if you can join NCT06784895 on ClinicalTrials.gov

16. Prevention of Progression of Prediabetes, Obesity and CV Risk

    The investigators are studying how to help people with prediabetes (Pre-DM) and obesity. The goal is to use new and affordable treatments to bring blood sugar levels back to normal and help participants to lose weight. The investigators also want to reduce participants risk of heart problems. The s…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    University of Texas Health Science Center at San Antonio, San Antonio, Texas

    Run by

    The University of Texas Health Science Center at San Antonio

    See if you can join NCT06446531 on ClinicalTrials.gov

17. A Study of Mayo Clinic CV Research Heart & Voice Study

    The purpose of the study is to determine whether voice recordings acquired from patient-owned Android and Apple (iOS) smartphones can be used to monitor cardiovascular health. Voice signals will be processed to determine whether we can detect presence of cardiovascular disease and wellness, or if h…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT07224685 on ClinicalTrials.gov

18. Gut Microbiota in Metabolic Surgery

    Metabolic surgery is an emerging option to treat obesity-related metabolic diseases (e.g., type 2 diabetes) and prevent cardiovascular disease (CVD). Metabolic surgery can profoundly alter the gut microbiota; meanwhile, gut microbiota may affect surgical outcomes. Longitudinal studies that examined…

    Stage

    Not phased

    Ages

    21 to 65

    Site

    Vanderbilt_University MC, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT05000996 on ClinicalTrials.gov

19. Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

    Cardiac rehabilitation (CR) is a secondary prevention program for patients with cardiovascular disease (CVD). It is especially valuable as CVD increasingly occurs in combination with comorbidity, frailty, and complexities of care that predispose patients to functional decline, disability, and high …

    Stage

    Not phased

    Ages

    18 and older

    Site

    VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts

    Locations

    2 in total

    Run by

    VA Office of Research and Development

    See if you can join NCT06244199 on ClinicalTrials.gov

20. The Weight of Cardiovascular Disease

    The purpose of this study is to evaluate the impact of a cardiometabolic clinic on percent body weight loss, body mass index (BMI), and visceral adiposity distribution in obese adults with cardiovascular disease (CVD) at 12 months.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT06053645 on ClinicalTrials.gov

21. Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

    Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having …

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06055036 on ClinicalTrials.gov

22. Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

    Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of this protein results in glucosuria and lower serum blood sugar. The SGLT2i medications were initially approved to treat type 2 diabetes (T2…

    Stage

    EARLY_Phase 1

    Ages

    60 and older

    Site

    University of Minnesota, Minneapolis, Minnesota

    Run by

    University of Minnesota

    See if you can join NCT06507657 on ClinicalTrials.gov

23. Philly CEAL- DECIDE+ Adaptation

    Cardiovascular disease (CVD) disproportionately affects racial/ethnic minorities and underserved populations in Philadelphia. This study aims to evaluate the effectiveness of an enhanced community health worker (CHW) program that combines the evidence-based DECIDE self-management intervention with …

    Stage

    Not phased

    Ages

    35 to 75

    Site

    University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT06732102 on ClinicalTrials.gov

24. Home-Based Cardiac Rehabilitation for Patients With Heart Failure

    The vast majority of individuals with heart failure do not participate in center based cardiac rehabilitation (CBCR). While steps to increase utilization of CBCR are important, many individuals will still not participate for a variety of reasons. This pilot randomized controlled trial is evaluating…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT06479876 on ClinicalTrials.gov

25. Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV

    Older people with HIV (OPWH) are disproportionately impacted by cardiovascular disease (CVD) attributable to behavioral risk factors, and chronic HIV immune dysregulation resulting inflammation. Systemic inflammation is exacerbated by psychological distress via activating the immune response and dr…

    Stage

    Not phased

    Ages

    50 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT06001814 on ClinicalTrials.gov