Cardiovascular Diseases Clinical Trials

121 studies are recruiting for cardiovascular diseases in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics

   This project will conduct a pilot hybrid study that examines the implementation (Aims 1 \& 2) and preliminary effectiveness (Aim 3) of PREVENT, a digital health intervention, among patients with overweight/obesity (N=100) using a clinic-randomized design. The central hypothesis of the study is that…

   Stage

   Not phased

   Ages

   18 to 64

   Site

   Washington University in St. Louis, St Louis, Missouri

   Run by

   Washington University School of Medicine

   See if you can join NCT06397729 on ClinicalTrials.gov

2. Adapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics

   The focus on this application is low-income, rural patients, since cardiovascular disease (CVD) prevalence is 40% higher among rural than urban residents. Health behavior counseling and follow-up care are required for patients with an elevated body mass index who have increased risk for CVD. Counse…

   Stage

   Not phased

   Ages

   18 to 64

   Site

   Washington University in St. Louis, St Louis, Missouri

   Run by

   Washington University School of Medicine

   See if you can join NCT06063564 on ClinicalTrials.gov

3. The RADIANCE CED Study

   The RADIANCE CED study is a prospective observational study designed to evaluate the long-term effectiveness of ultrasound renal denervation in lowering blood pressure among patients with uncontrolled hypertension. Data will be collected from electronic health records (EHRs) of Medicare-eligible pa…

   Stage

   Not phased

   Ages

   65 and older

   Site

   Henry Ford Hospital, Detroit, Michigan

   Locations

   2 in total

   Run by

   ReCor Medical, Inc.

   See if you can join NCT07231757 on ClinicalTrials.gov

4. Aging, Geriatric Syndromes and Clonal Hematopoiesis

   In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, whi…

   Stage

   Not phased

   Ages

   50 and older

   Site

   Washington University School of Medicine, St Louis, Missouri

   Run by

   Washington University School of Medicine

   See if you can join NCT02604563 on ClinicalTrials.gov

5. Healthy School Recognized Campus: A Hybrid Type 2 Implementation-Effectiveness Trial

   Healthy School Recognized Campus is a Texas A\&M AgriLife Extension initiative that supports the delivery of school-based physical activity and nutrition programs for diverse youth across Texas. The purpose of this study is to conduct a type 2 hybrid implementation-effectiveness, cluster dual rando…

   Stage

   Not phased

   Ages

   8 to 16

   Site

   Texas A&M AgriLife Dallas Center, Dallas, Texas

   Run by

   Texas A&M University

   See if you can join NCT07079995 on ClinicalTrials.gov

6. Cardiovascular and Metabolic Sciences Biorepository

   The purpose of the Cardiovascular and Metabolic Sciences Biorepository is to collect and store information and biospecimens (blood, urine, stool, and heart tissue) from patients with and without cardiovascular and metabolic diseases to create a readily available biorepository of samples and related…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cleveland Clinic Main Campus, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT06560424 on ClinicalTrials.gov

7. Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy

   Cardiovascular disease is the leading cause of death among women in the United States, and women with hypertensive disorders of pregnancy have a 2-fold higher risk for cardiovascular disease later in life compared to women with uncomplicated pregnancies. This research investigates a patient-centere…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Utah Hospital, Salt Lake City, Utah

   Run by

   University of Utah

   See if you can join NCT05826925 on ClinicalTrials.gov

8. EVOC - EVs in Obesity and Cardiometabolic Disease

   The goal of this observational study is to research the impact of molecular signals from the heart, liver and fat tissue on cardiovascular disease risk, and the presentation of Type II Diabetes and diseases that affect the heart, blood vessels and metabolism (Cardiometabolic Disease). Specifically,…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT06408961 on ClinicalTrials.gov

9. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

   The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Banner-University Medical Center Phoenix, Phoenix, Arizona

   Locations

   68 in total

   Run by

   Abbott Medical Devices

   See if you can join NCT06526195 on ClinicalTrials.gov

10. Brain Connections for Arm Movement After Stroke

    The purpose of this study is to use Transcranial Magnetic Stimulation (TMS) while subjects are making reaching movements in a robotic arm device in order to discover how different brain areas control movement before and after stroke and when these brain areas are most sensitive to TMS.

    Stage

    Not phased

    Ages

    45 to 90

    Site

    VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh, Pennsylvania

    Run by

    VA Office of Research and Development

    See if you can join NCT04286516 on ClinicalTrials.gov

11. Global Cardio Oncology Registry

    G-COR is the first Global Prospective Cardio-Oncology Registry. It is a multinational, multicenter prospective observational cohort registry, with the goal of collecting clinical, laboratory, imaging, demographic, and socioeconomic data to identify risk factors associated with increased incidence o…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cleveland Clinic Florida, Weston, Florida

    Run by

    The Cleveland Clinic

    See if you can join NCT05598879 on ClinicalTrials.gov

12. CV Imaging of Metabolic Interventions

    Cardiovascular disease is the leading cause of death worldwide. It is becoming clearer that heart failure (HF) is closely associated with body's metabolism. Even before the heart becomes weaker, it responds to the stresses by changing the fuels it burns, which results in a reduction in the heart's …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cardiovascular Innovation Research Center, Cleveland, Ohio

    Run by

    The Cleveland Clinic

    See if you can join NCT05650307 on ClinicalTrials.gov

13. Development of CIRC Technologies

    Cardiovascular disease is the leading cause of death worldwide. Advanced cardiovascular imaging using Magnetic Resonance Imaging (MRI) has proven to be effective in providing gold standard myocardial tissue characterization. Moreover, the intrinsic advantage of MRI's lack of exposure to ionizing ra…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cardiovascular Innovation Research Center, Cleveland, Ohio

    Run by

    The Cleveland Clinic

    See if you can join NCT05654272 on ClinicalTrials.gov

14. Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

    The goal of this study is to verify whether the use of deep brain stimulation can improve motor function of the hand and arm and speech abilities for people following a stroke. Participants will undergo a surgical procedure to implant deep brain stimulation electrode leads. The electrodes will be c…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    University of Pittsburgh, Pittsburgh, Pennsylvania

    Run by

    Jorge Gonzalez-Martinez

    See if you can join NCT06303869 on ClinicalTrials.gov

15. Cardiovascular Health Improvement Project

    The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

    Stage

    Not phased

    Ages

    Any age

    Site

    University of Michigan, Ann Arbor, Michigan

    Run by

    University of Michigan

    See if you can join NCT02306200 on ClinicalTrials.gov

16. SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation

    The study is sponsored by the National Heart, Lung, and Blood Institute, which is part of the National Institutes of Health. The study expects to enroll 400 subjects. The research team will recruit research participants that are finishing or will finish cardiac rehabilitation soon. Participants bel…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Weight Control and Diabetes Research Center of The Miriam Hospital, Providence, Rhode Island

    Run by

    The Miriam Hospital

    See if you can join NCT06886789 on ClinicalTrials.gov

17. Mayo AVC Registry and Biobank

    Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous. Diagnosis and screening of blood-relatives is very difficult as the disease pr…

    Stage

    Not phased

    Ages

    Any age

    Site

    Mayo Clinic, Rochester, Minnesota

    Locations

    2 in total

    Run by

    Mayo Clinic

    See if you can join NCT03049254 on ClinicalTrials.gov

18. Pivotal Study for the Cardiac Performance System (CPS)

    This multi-center, observational study evaluates the accuracy of the Cardiac Performance System (CPS), a non-invasive device, for measuring hemodynamic parameters in adult patients undergoing clinically indicated right heart catheterization. The study compares CPS measurements to invasive measureme…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Huntsville Hospital Heart Center, Huntsville, Alabama

    Locations

    10 in total

    Run by

    Sensydia Corporation

    See if you can join NCT06870591 on ClinicalTrials.gov

19. DeBakey Cardiovascular Magnetic Resonance Study

    While advancements in cardiac magnetic resonance (CMR) have improved image quality, it is unclear how these improvements are connected to the clinical evaluation of individuals with cardiovascular disease. The aim of this large prospective registry revolves around 4 key principles: 1) utilize CMR t…

    Stage

    Not phased

    Ages

    Any age

    Site

    Houston Methodist Hospital, Houston, Texas

    Run by

    Dipan Shah

    See if you can join NCT04281823 on ClinicalTrials.gov

20. HARP Mindfulness Study

    This study was designed using the Multiphase Optimization Strategy (MOST) framework to determine whether two supplemental components increase the efficacy of a mindfulness-based cognitive therapy program delivered via telephone (MBCT-T) for psychological distress. Specifically, this study will test…

    Stage

    Not phased

    Ages

    18 and older

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT05841784 on ClinicalTrials.gov

21. Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

    This pilot pre-post trial will address a gap in knowledge related to addressing modifiable risk factors for cardiometabolic disease through treating residual insomnia, sleep difficulties that remain after successful treatment of another condition, in the context of PTSD in understudied older adults…

    Stage

    Not phased

    Ages

    50 and older

    Site

    VA Greater Los Angeles Healthcare System, North Hills, California

    Run by

    University of California, Los Angeles

    See if you can join NCT05516277 on ClinicalTrials.gov

22. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona

    Locations

    92 in total

    Run by

    Cardiac Dimensions, Inc.

    See if you can join NCT03142152 on ClinicalTrials.gov

23. Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

    The purpose of this study is to determine which of the following four service models is most effective for reducing fall risk among home-delivered meal clients: (1) meals alone, (2) meals + registered dietitian services, (3) meals + occupational therapy services, (4) meals + registered dietitian + …

    Stage

    Not phased

    Ages

    60 and older

    Site

    LifeCare Alliance, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06586970 on ClinicalTrials.gov

24. PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

    Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death. Natriuretic Peptides (NPs) are hormones produced by the heart which directly regulate BP by causi…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT04971720 on ClinicalTrials.gov

25. Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

    AliveCor (www.alivecor.com) has developed several electrocardiogram (ECG) devices that interface with iOS and Android smartphones and tablets via various Kardia apps. The current Kardia family of devices can measure single lead and six limb-lead ECGs, depending on the device. KardiaMobile, KardiaMo…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic, Rochester, Minnesota

    Locations

    4 in total

    Run by

    AliveCor

    See if you can join NCT06271577 on ClinicalTrials.gov