Cardiovascular Diseases Clinical Trials

125 studies are recruiting for cardiovascular diseases in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. Global Cardio Oncology Registry

   G-COR is the first Global Prospective Cardio-Oncology Registry. It is a multinational, multicenter prospective observational cohort registry, with the goal of collecting clinical, laboratory, imaging, demographic, and socioeconomic data to identify risk factors associated with increased incidence o…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cleveland Clinic Florida, Weston, Florida

   Run by

   The Cleveland Clinic

   See if you can join NCT05598879 on ClinicalTrials.gov

2. CV Imaging of Metabolic Interventions

   Cardiovascular disease is the leading cause of death worldwide. It is becoming clearer that heart failure (HF) is closely associated with body's metabolism. Even before the heart becomes weaker, it responds to the stresses by changing the fuels it burns, which results in a reduction in the heart's …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cardiovascular Innovation Research Center, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT05650307 on ClinicalTrials.gov

3. Development of CIRC Technologies

   Cardiovascular disease is the leading cause of death worldwide. Advanced cardiovascular imaging using Magnetic Resonance Imaging (MRI) has proven to be effective in providing gold standard myocardial tissue characterization. Moreover, the intrinsic advantage of MRI's lack of exposure to ionizing ra…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cardiovascular Innovation Research Center, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT05654272 on ClinicalTrials.gov

4. Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

   The goal of this study is to verify whether the use of deep brain stimulation can improve motor function of the hand and arm and speech abilities for people following a stroke. Participants will undergo a surgical procedure to implant deep brain stimulation electrode leads. The electrodes will be c…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   Jorge Gonzalez-Martinez

   See if you can join NCT06303869 on ClinicalTrials.gov

5. Cardiovascular Health Improvement Project

   The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

   Stage

   Not phased

   Ages

   Any age

   Site

   University of Michigan, Ann Arbor, Michigan

   Run by

   University of Michigan

   See if you can join NCT02306200 on ClinicalTrials.gov

6. SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation

   The study is sponsored by the National Heart, Lung, and Blood Institute, which is part of the National Institutes of Health. The study expects to enroll 400 subjects. The research team will recruit research participants that are finishing or will finish cardiac rehabilitation soon. Participants bel…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Weight Control and Diabetes Research Center of The Miriam Hospital, Providence, Rhode Island

   Run by

   The Miriam Hospital

   See if you can join NCT06886789 on ClinicalTrials.gov

7. Mayo AVC Registry and Biobank

   Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous. Diagnosis and screening of blood-relatives is very difficult as the disease pr…

   Stage

   Not phased

   Ages

   Any age

   Site

   Mayo Clinic, Rochester, Minnesota

   Locations

   2 in total

   Run by

   Mayo Clinic

   See if you can join NCT03049254 on ClinicalTrials.gov

8. Pivotal Study for the Cardiac Performance System (CPS)

   This multi-center, observational study evaluates the accuracy of the Cardiac Performance System (CPS), a non-invasive device, for measuring hemodynamic parameters in adult patients undergoing clinically indicated right heart catheterization. The study compares CPS measurements to invasive measureme…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Huntsville Hospital Heart Center, Huntsville, Alabama

   Locations

   10 in total

   Run by

   Sensydia Corporation

   See if you can join NCT06870591 on ClinicalTrials.gov

9. Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

   This observational study will assess the long-term effectiveness of the RDN procedure for lowering blood pressure in Medicare patients with uncontrolled hypertension. This research will be conducted using de-identified electronic health records (EHR) and administrative health insurance claims data.…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Beth Israel Deaconess Medical Center, Boston, Massachusetts

   Run by

   Medtronic Vascular

   See if you can join NCT07174622 on ClinicalTrials.gov

10. DeBakey Cardiovascular Magnetic Resonance Study

    While advancements in cardiac magnetic resonance (CMR) have improved image quality, it is unclear how these improvements are connected to the clinical evaluation of individuals with cardiovascular disease. The aim of this large prospective registry revolves around 4 key principles: 1) utilize CMR t…

    Stage

    Not phased

    Ages

    Any age

    Site

    Houston Methodist Hospital, Houston, Texas

    Run by

    Dipan Shah

    See if you can join NCT04281823 on ClinicalTrials.gov

11. HARP Mindfulness Study

    This study was designed using the Multiphase Optimization Strategy (MOST) framework to determine whether two supplemental components increase the efficacy of a mindfulness-based cognitive therapy program delivered via telephone (MBCT-T) for psychological distress. Specifically, this study will test…

    Stage

    Not phased

    Ages

    18 and older

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT05841784 on ClinicalTrials.gov

12. Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

    This pilot pre-post trial will address a gap in knowledge related to addressing modifiable risk factors for cardiometabolic disease through treating residual insomnia, sleep difficulties that remain after successful treatment of another condition, in the context of PTSD in understudied older adults…

    Stage

    Not phased

    Ages

    50 and older

    Site

    VA Greater Los Angeles Healthcare System, North Hills, California

    Run by

    University of California, Los Angeles

    See if you can join NCT05516277 on ClinicalTrials.gov

13. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona

    Locations

    92 in total

    Run by

    Cardiac Dimensions, Inc.

    See if you can join NCT03142152 on ClinicalTrials.gov

14. Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

    The purpose of this study is to determine which of the following four service models is most effective for reducing fall risk among home-delivered meal clients: (1) meals alone, (2) meals + registered dietitian services, (3) meals + occupational therapy services, (4) meals + registered dietitian + …

    Stage

    Not phased

    Ages

    60 and older

    Site

    LifeCare Alliance, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06586970 on ClinicalTrials.gov

15. PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

    Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death. Natriuretic Peptides (NPs) are hormones produced by the heart which directly regulate BP by causi…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT04971720 on ClinicalTrials.gov

16. GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study

    Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes and poor cardiometabolic health. Obese and Black individuals have ~30% …

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT05216042 on ClinicalTrials.gov

17. Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

    AliveCor (www.alivecor.com) has developed several electrocardiogram (ECG) devices that interface with iOS and Android smartphones and tablets via various Kardia apps. The current Kardia family of devices can measure single lead and six limb-lead ECGs, depending on the device. KardiaMobile, KardiaMo…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic, Rochester, Minnesota

    Locations

    4 in total

    Run by

    AliveCor

    See if you can join NCT06271577 on ClinicalTrials.gov

18. BLOOM: Biological Legacy of Origin in Mother-Infant Dyads

    Infants born preterm and of low birth weight are known to be at increased risk for early onset of cardiovascular and renal disease in adult life. This has been related to low nephron mass due to inadequate or early termination of glomerulogenesis in utero and during the perinatal period. Risks for …

    Stage

    Not phased

    Ages

    Up to 10

    Site

    University of Miami/ Holtz Children's Hospital, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT02000895 on ClinicalTrials.gov

19. Enhancing Capacity in Churches to Implement PA Programs

    Despite the benefits of physical activity (PA) to prevent cardiovascular disease and other chronic diseases, few adult Latinas meet PA guidelines. Given the central role of churches within the Latino community and their commitment to the well-being of their members, they are ideal settings for heal…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    San Diego State University Research Foundation, San Diego, California

    Run by

    San Diego State University

    See if you can join NCT05473871 on ClinicalTrials.gov

20. A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)

    This study will investigate the acceptability and efficacy of 12 weeks of: Smart-device app-based (MyZone) Asynchronous Virtual, Synchronous Virtual, and in-person aerobic training in individuals at risk for Cardiovascular Disease (CVD) who do are not meeting American Heart Association (AHA) guidel…

    Stage

    Not phased

    Ages

    45 and older

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT06931470 on ClinicalTrials.gov

21. Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial

    Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders (EMERALD) is a protocolized intervention based on American College of Cardiology/American Heart Association and US Preventive Services Task Force guidelines designed to initiate preventive cardiovascular care for emergency depart…

    Stage

    Phase 2

    Ages

    40 to 75

    Site

    Wake Forest University Health Sciences, Winston-Salem, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT06488105 on ClinicalTrials.gov

22. PKP2-ACM Natural History Study

    The goal of this study is to describe the natural history and clinical events for patients who have Arrhythmogenic Cardiomyopathy with Pathogenic Plakophilin-2 Variants (PKP2-ACM) managed with standard of care.

    Stage

    Not phased

    Ages

    12 and older

    Site

    Boston Children's Hospital, Boston, Massachusetts

    Locations

    3 in total

    Run by

    Rocket Pharmaceuticals Inc.

    See if you can join NCT06644742 on ClinicalTrials.gov

23. Food and Microbiome Longitudinal Investigation (FAMiLI)

    The NYU Human Microbiome Study Cohort is designed to improve understanding of the role of human microbiome in health and disease. This study will serve as a critical NYU biorepository resource for research on human genetics and the microbiome in health and disease

    Stage

    Not phased

    Ages

    40 and older

    Site

    New York University School of Medicine, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT03293758 on ClinicalTrials.gov

24. WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time

    The purpose of this study is to determine the feasibility, acceptability, efficacy, and participant adherence in using home-based technologies and wearable devices and simple, practical strategies to reduce the negative impact that evening screen time may have on your health.

    Stage

    Not phased

    Ages

    26 and older

    Site

    Arizona State University, Tempe, Arizona

    Run by

    Arizona State University

    See if you can join NCT06963736 on ClinicalTrials.gov

25. Chardonnay Marc and Vascular Response

    This study aims to obtain data on the potential influence of Vine to Bar product(s) containing Chardonnay marc on cardiometabolic health. These initial studies will inform the design and timing of data collection for future dietary intervention trials that will examine the influence of Chardonnay m…

    Stage

    Not phased

    Ages

    30 to 50

    Site

    Academic Surge, University of California, Davis, Davis, California

    Run by

    University of California, Davis

    See if you can join NCT05545865 on ClinicalTrials.gov