Cardiovascular Diseases Clinical Trials in Minneapolis, Minnesota

7 studies are recruiting for cardiovascular diseases in Minneapolis, Minnesota right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

   The goal of this study is to evaluate the safety and efficacy of the BrioVAD System by demonstrating non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart failure.

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Abbott Northwestern Hospital, Minneapolis, Minnesota

   Locations

   47 in total

   Run by

   BrioHealth Solutions, Inc.

   See if you can join NCT06310031 on ClinicalTrials.gov

2. A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

   The OPTIMAL randomized clinical trial has been designed to compare two imaging strategies and to test the hypothesis that a calcium modification strategy informed by coronary CT angiography (CCTA) will improve procedural efficiency and effectiveness compared with the current standard of care (IVUS-…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Minneapolis Heart Institute, Minneapolis, Minnesota

   Locations

   14 in total

   Run by

   Fundación EPIC

   See if you can join NCT07286578 on ClinicalTrials.gov

3. Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

   PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the …

   Stage

   Phase 4

   Ages

   75 and older

   Site

   Allina Health, Minneapolis, Minnesota

   Locations

   106 in total

   Run by

   Duke University

   See if you can join NCT04262206 on ClinicalTrials.gov

4. The TRICURE EFS Study

   Prospective, multi-center study to assess safety and performance of the TRiCares Topaz Tricuspid Valve Replacement System

   Stage

   Not phased

   Ages

   18 and older

   Site

   Minneapolis Heart Institute Foundation, Minneapolis, Minnesota

   Locations

   10 in total

   Run by

   TRiCares

   See if you can join NCT06506942 on ClinicalTrials.gov

5. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

   The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Minneapolis Heart Institute, Minneapolis, Minnesota

   Locations

   68 in total

   Run by

   Abbott Medical Devices

   See if you can join NCT06526195 on ClinicalTrials.gov

6. Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

   Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of this protein results in glucosuria and lower serum blood sugar. The SGLT2i medications were initially approved to treat type 2 diabetes (T2…

   Stage

   EARLY_Phase 1

   Ages

   60 and older

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT06507657 on ClinicalTrials.gov

7. MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

   A Prospective, Multicenter, Randomized, Two-Arm, Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch™ Sirolimus- Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis. Subjects with prior DES implantation presenting with ISR lesions unde…

   Stage

   Not phased

   Ages

   18 to 110

   Site

   Minneapolis Heart Institute Foundation, Minneapolis, Minnesota

   Locations

   28 in total

   Run by

   Concept Medical Inc.

   See if you can join NCT05908331 on ClinicalTrials.gov