Cardiovascular Diseases Clinical Trials in Los Angeles, California

7 studies are recruiting for cardiovascular diseases in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

   The goal of this study is to evaluate the safety and efficacy of the BrioVAD System by demonstrating non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart failure.

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   47 in total

   Run by

   BrioHealth Solutions, Inc.

   See if you can join NCT06310031 on ClinicalTrials.gov

2. Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

   PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the …

   Stage

   Phase 4

   Ages

   75 and older

   Site

   VA Greater Los Angeles, Los Angeles, California

   Locations

   106 in total

   Run by

   Duke University

   See if you can join NCT04262206 on ClinicalTrials.gov

3. Global Paradise System US Post Approval Study

   The objective of the Global Paradise® System US Post Approval Study (US GPS) is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This system is comprised of a…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   43 in total

   Run by

   ReCor Medical, Inc.

   See if you can join NCT06297291 on ClinicalTrials.gov

4. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

   The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).

   Stage

   Not phased

   Ages

   18 and older

   Site

   Keck School of Medicine of USC, Los Angeles, California

   Locations

   92 in total

   Run by

   Cardiac Dimensions, Inc.

   See if you can join NCT03142152 on ClinicalTrials.gov

5. Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

   This is a randomized placebo-controlled study in treated and suppressed HIV-infected individuals aged ≥40 years with either known CVD or 1 CVD risk factor to study the effect of Bempedoic acid (BA) on safety, arterial inflammation as assessed by FDG-PET/CT, lipids, inflammation, immune activation, …

   Stage

   Phase 2

   Ages

   40 and older

   Site

   UCLA Center for Clinical AIDS Research and Education (CARE), Los Angeles, California

   Locations

   3 in total

   Run by

   Priscilla Hsue, MD

   See if you can join NCT05488431 on ClinicalTrials.gov

6. MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

   This is a multicenter, randomized, single-blind pivotal study to evaluate the safety and efficacy of the MagicTouchTM Drug coated balloon in treatment of small vessels in patients with coronary artery disease. The objective is to establish the safety and efficacy of the Magic TouchTM Drug coated ba…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   24 in total

   Run by

   Concept Medical Inc.

   See if you can join NCT06271590 on ClinicalTrials.gov

7. MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

   A Prospective, Multicenter, Randomized, Two-Arm, Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch™ Sirolimus- Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis. Subjects with prior DES implantation presenting with ISR lesions unde…

   Stage

   Not phased

   Ages

   18 to 110

   Site

   Cedars - Sinai Medical Center, Los Angeles, California

   Locations

   28 in total

   Run by

   Concept Medical Inc.

   See if you can join NCT05908331 on ClinicalTrials.gov