Cardiovascular Diseases Clinical Trials in Cleveland, Ohio

15 studies are recruiting for cardiovascular diseases in Cleveland, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

   The goal of this study is to evaluate the safety and efficacy of the BrioVAD System by demonstrating non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart failure.

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Cleveland Clinic, Cleveland, Ohio

   Locations

   47 in total

   Run by

   BrioHealth Solutions, Inc.

   See if you can join NCT06310031 on ClinicalTrials.gov

2. Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

   PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the …

   Stage

   Phase 4

   Ages

   75 and older

   Site

   Case Western Reserve University, Cleveland, Ohio

   Locations

   106 in total

   Run by

   Duke University

   See if you can join NCT04262206 on ClinicalTrials.gov

3. A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

   The goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiofrequency Ablation Enhancor System in patients with combined pre- and post-capillary pulmonary hypertension (CpcPH) associated with left hear…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Cleveland Clinic, Cleveland, Ohio

   Locations

   6 in total

   Run by

   Pulnovo Medical, Inc.

   See if you can join NCT07214376 on ClinicalTrials.gov

4. The Oxford Risk Factors And Non-Invasive Imaging Study

   ORFAN is a prospective, multi-centre, multi-ethnic cohort observational study collecting CT scans, biological material and outcomes data, to develop and validate novel biomarkers of cardiometabolic and other disease risk.

   Stage

   Not phased

   Ages

   18 to 99

   Site

   Cleveland Clinic, Cleveland, Ohio

   Locations

   45 in total

   Run by

   University of Oxford

   See if you can join NCT05169333 on ClinicalTrials.gov

5. Longitudinal Validation of CIRC Technologies

   Cardiovascular disease is the leading cause of death worldwide. Advanced cardiovascular imaging using Magnetic Resonance Imaging (MRI) has proven to be effective in providing gold standard myocardial tissue characterization. Moreover, the intrinsic advantage of MRI's lack of exposure to ionizing ra…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cleveland Clinic, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT07081711 on ClinicalTrials.gov

6. Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)

   VahatiCor's Coronary Sinus Reducer (A-FLUX) has been designed to improve angina or angina-like symptoms in patients with CMD. SERRA-I is an early feasibility study that evaluates the safety and clinical performance of the A-FLUX Reducer in this population.

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Cleveland Clinic Foundation, Cleveland, Ohio

   Locations

   3 in total

   Run by

   VahatiCor, Inc.

   See if you can join NCT07449325 on ClinicalTrials.gov

7. Cardiovascular and Metabolic Sciences Biorepository

   The purpose of the Cardiovascular and Metabolic Sciences Biorepository is to collect and store information and biospecimens (blood, urine, stool, and heart tissue) from patients with and without cardiovascular and metabolic diseases to create a readily available biorepository of samples and related…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cleveland Clinic Main Campus, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT06560424 on ClinicalTrials.gov

8. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

   The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Cleveland Clinic Foundation, Cleveland, Ohio

   Locations

   68 in total

   Run by

   Abbott Medical Devices

   See if you can join NCT06526195 on ClinicalTrials.gov

9. CV Imaging of Metabolic Interventions

   Cardiovascular disease is the leading cause of death worldwide. It is becoming clearer that heart failure (HF) is closely associated with body's metabolism. Even before the heart becomes weaker, it responds to the stresses by changing the fuels it burns, which results in a reduction in the heart's …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cardiovascular Innovation Research Center, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT05650307 on ClinicalTrials.gov

10. Development of CIRC Technologies

    Cardiovascular disease is the leading cause of death worldwide. Advanced cardiovascular imaging using Magnetic Resonance Imaging (MRI) has proven to be effective in providing gold standard myocardial tissue characterization. Moreover, the intrinsic advantage of MRI's lack of exposure to ionizing ra…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cardiovascular Innovation Research Center, Cleveland, Ohio

    Run by

    The Cleveland Clinic

    See if you can join NCT05654272 on ClinicalTrials.gov

11. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cleveland Clinic, Cleveland, Ohio

    Locations

    92 in total

    Run by

    Cardiac Dimensions, Inc.

    See if you can join NCT03142152 on ClinicalTrials.gov

12. Vascular Lab Resource (VLR) Biorepository

    This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases. The purpose of this initiative is to develop an enduring tool to allow for collaborative research between clinicians at Cleveland Clinic Main Campus …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cleveland Clinic, Cleveland, Ohio

    Run by

    The Cleveland Clinic

    See if you can join NCT05628948 on ClinicalTrials.gov

13. MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

    This is a multicenter, randomized, single-blind pivotal study to evaluate the safety and efficacy of the MagicTouchTM Drug coated balloon in treatment of small vessels in patients with coronary artery disease. The objective is to establish the safety and efficacy of the Magic TouchTM Drug coated ba…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    University Hospitals, Cleveland Medical Center, Cleveland, Ohio

    Locations

    24 in total

    Run by

    Concept Medical Inc.

    See if you can join NCT06271590 on ClinicalTrials.gov

14. MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

    A Prospective, Multicenter, Randomized, Two-Arm, Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch™ Sirolimus- Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis. Subjects with prior DES implantation presenting with ISR lesions unde…

    Stage

    Not phased

    Ages

    18 to 110

    Site

    Cleveland Clinic, Cleveland, Ohio

    Locations

    28 in total

    Run by

    Concept Medical Inc.

    See if you can join NCT05908331 on ClinicalTrials.gov

15. Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"

    This is an international prospective, multicentre, unblinded, randomised-controlled trial. The primary aim is to assess a targeted screening strategy to detect undiagnosed heart failure in high-risk patients.

    Stage

    Not phased

    Ages

    40 and older

    Site

    Cleveland Clinic, Cleveland, Ohio

    Locations

    7 in total

    Run by

    NHS Greater Glasgow and Clyde

    See if you can join NCT05919342 on ClinicalTrials.gov