Cardiovascular Diseases Clinical Trials

125 studies are recruiting for cardiovascular diseases in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 5

1. Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments

   Strong Teens for Healthy Schools (STHS) is a school-based, civic engagement program that empowers middle school students to improve their physical activity and healthy eating behaviors, improve their cardiovascular disease outcomes, and create positive change in their school health environments.

   Stage

   Not phased

   Ages

   8 and older

   Site

   Texas A&M AgriLife Dallas Center, Dallas, Texas

   Run by

   Texas A&M University

   See if you can join NCT05867433 on ClinicalTrials.gov

2. NightWare and Cardiovascular Health in Veterans With PTSD

   The purpose of this study is to learn more about the effectiveness of a prescription wrist-wearable device called NightWare (NW) on improving sleep in Veterans with nightmares related to posttraumatic stress disorder (PTSD). The investigators also want to learn whether it improves cardiovascular he…

   Stage

   Not phased

   Ages

   22 to 88

   Site

   Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado

   Run by

   VA Office of Research and Development

   See if you can join NCT06419959 on ClinicalTrials.gov

3. MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

   This is a multicenter, randomized, single-blind pivotal study to evaluate the safety and efficacy of the MagicTouchTM Drug coated balloon in treatment of small vessels in patients with coronary artery disease. The objective is to establish the safety and efficacy of the Magic TouchTM Drug coated ba…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Clearwater Cardiovascular and Interventional Consultants, Clearwater, Florida

   Locations

   24 in total

   Run by

   Concept Medical Inc.

   See if you can join NCT06271590 on ClinicalTrials.gov

4. The Cooking for Health Optimization and Disease Prevention (CHOP) Trial

   Poor nutrition-related diseases disproportionately impact seniors and racial/ethnic minorities who are more likely to experience disparities in proper nutrition. Culinary medicine is a new evidence-based educational approach that blends the art of food and cooking with the science of medicine. Rece…

   Stage

   Not phased

   Ages

   55 to 120

   Site

   The Goldring Center for Culinary Medicine, New Orleans, Louisiana

   Locations

   2 in total

   Run by

   Tulane University

   See if you can join NCT07011459 on ClinicalTrials.gov

5. Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study

   The Active Older Adults prospective cohort study examines the effects of a park-based fitness program on cardiovascular fitness outcomes for older adults (aged 50 years and older). Duke will perform a secondary analysis of the data collected as part of the Active Older Adults prospective cohort stu…

   Stage

   Not phased

   Ages

   50 to 95

   Site

   Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida

   Run by

   Duke University

   See if you can join NCT06604650 on ClinicalTrials.gov

6. The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

   This project will investigate the effect of spinal cord transcutaneous stimulation on blood pressure in individuals with a chronic spinal cord injury who experience blood pressure instability, specifically, orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back t…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Kessler Foundation, West Orange, New Jersey

   Run by

   Kessler Foundation

   See if you can join NCT05725499 on ClinicalTrials.gov

7. Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

   The goal of this clinical trial is to evaluate the effect of transcutaneous spinal cord stimulation on blood pressure in individuals with an acute spinal cord injury (within 30 days of injury). Blood pressure instability, specifically orthostatic hypotension (a drop in blood pressure when moving ly…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Kessler Foundation, West Orange, New Jersey

   Run by

   Kessler Foundation

   See if you can join NCT05731986 on ClinicalTrials.gov

8. Techquity by FAITH!

   The goal of this clinical trial is to engage African-American churches via an established community-academic partnership (FAITH! Program) to build capacity to promote cardiovascular health and digital health equity in African-American faith communities. There are 3 study aims: Aim 1: Co-design a cu…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT06187077 on ClinicalTrials.gov

9. Wellness Intervention for Smoking and HIV

   The investigators propose to use a parallel group, randomized controlled trial to test the efficacy of a 13-week personalized approach to reducing smoking intervention versus a second approach using a different health intervention on smoking cessation, healthy sleep metrics, and biomarkers of cardi…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Banner University Medical Center Phoenix, Phoenix, Arizona

   Locations

   2 in total

   Run by

   University of Arizona

   See if you can join NCT04725617 on ClinicalTrials.gov

10. Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.

    DOVE-MET-COME-100 is a single site prescreening survey study designed to identify adults who may be eligible for future industry-sponsored clinical trials. A physician will oversee the informed consent process, after which participants will be surveyed on demographics, medical history, current heal…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Clindove Research LLC, Brooklyn, New York

    Run by

    Clindove Research LLC

    See if you can join NCT07106879 on ClinicalTrials.gov

11. HIIT Effects on Cardiometabolic Health

    The primary aim of this randomized clinical trial is to compare the effects of three different HIIT protocols and a control group on cardiometabolic health in young adults with obesity. Participants will be randomly assigned to one of the following three groups, with each having varying work-to-res…

    Stage

    Not phased

    Ages

    18 to 25

    Site

    Women's Building, Syracuse, New York

    Run by

    Syracuse University

    See if you can join NCT05838950 on ClinicalTrials.gov

12. Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

    A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.

    Stage

    Phase 2

    Ages

    Any age

    Site

    Nationwide Children's Hospital, Columbus, Ohio

    Run by

    Nationwide Children's Hospital

    See if you can join NCT04467671 on ClinicalTrials.gov

13. MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

    Diabetic kidney disease and cardiovascular disease remain the leading causes of morbidity and mortality in people with type 1 diabetes and are exacerbated with longer duration of diabetes and time outside goal glycemic range. Yet, type 1 diabetes is a complex disease with pathophysiology that exten…

    Stage

    Phase 1

    Ages

    12 to 25

    Site

    Seattle Children's Hospital, Seattle, Washington

    Locations

    2 in total

    Run by

    Kalie Tommerdahl

    See if you can join NCT05065372 on ClinicalTrials.gov

14. Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)

    The main purpose of research is to examine and understanding the development of hypertension in obese adults with insulin resistance. Findings from our studies will identify unique mechanisms that can be targeted to limit increases in vascular dysfunction and reduce the excessively high prevalence …

    Stage

    Phase 1

    Ages

    35 to 65

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT04715022 on ClinicalTrials.gov

15. Text Education About Cardiovascular Health and HIV (TEACH-HIV)

    The overall objective is to evaluate the efficacy of educational text messages to reduce cardiovascular risk among persons living with HIV (PLWH).

    Stage

    Not phased

    Ages

    40 and older

    Site

    Zuckerberg San Francisco General Hospital, San Francisco, California

    Locations

    2 in total

    Run by

    University of California, San Francisco

    See if you can join NCT05642858 on ClinicalTrials.gov

16. MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

    A Prospective, Multicenter, Randomized, Two-Arm, Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch™ Sirolimus- Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis. Subjects with prior DES implantation presenting with ISR lesions unde…

    Stage

    Not phased

    Ages

    18 to 110

    Site

    Cardiology, PC - Princeton Baptist Medical Center, Birmingham, Alabama

    Locations

    28 in total

    Run by

    Concept Medical Inc.

    See if you can join NCT05908331 on ClinicalTrials.gov

17. Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

    The purpose of the study is to evaluate the efficacy of multiple human placental membrane products and Standard of Care (SOC) versus SOC alone in the management of nonhealing diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs) over 12 weeks using a modified platform trial design.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Poirot Podiatry, Metairie, Louisiana

    Run by

    C5 Biomedical

    See if you can join NCT06674980 on ClinicalTrials.gov

18. PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG

    To evaluate the proportion of diabetic mellitus patients with CV events as measured by HEMOTAG.

    Stage

    Not phased

    Ages

    40 and older

    Site

    Metabolic Research Institute, Inc, West Palm Beach, Florida

    Run by

    Aventusoft, LLC.

    See if you can join NCT06567795 on ClinicalTrials.gov

19. Role of Endothelial Function in SCI CVD Risk

    Individuals with spinal cord injury have heart attacks and strokes more frequently, and much earlier in life. People with spinal cord injuries develop plaque in vessels much faster, and the reasons why are unclear. Doctors generally attributed the increased risk with weight gain and developing diab…

    Stage

    Not phased

    Ages

    18 to 89

    Site

    Craig Hospital, Englewood, Colorado

    Run by

    Craig Hospital

    See if you can join NCT06443151 on ClinicalTrials.gov

20. A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

    The is a first clinical study for Oricell Therapeutics Inc. in the United States to evaluate the safety, PK, PD and preliminary efficacy of our anti-GPRC5D cell product (OriCAR-017) in subjects with relapsed/refractory multiple myeloma. RIGEL Study

    Stage

    Phase 1

    Ages

    18 to 75

    Site

    Northside Hospital, Atlanta, Georgia

    Run by

    OriCell Therapeutics Co., Ltd.

    See if you can join NCT06271252 on ClinicalTrials.gov

21. Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility

    SWIFT-CORE-101 is a single site survey study designed to assess potential participants' eligibility to screen for industry-sponsored clinical trials. A physician will oversee the informed consent process, after which participants will be surveyed on demographics, medical history, comorbidities, and…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Brooklyn Clinical Research, Brooklyn, New York

    Run by

    Brooklyn Clinical Research

    See if you can join NCT06412536 on ClinicalTrials.gov

22. Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs

    The goal of this prospective study is to evaluate whether the Intensive Cardiac Rehabilitation (ICR) program provides incremental benefits over the Traditional Cardiac Rehabilitation (TCR) program, defined by readmission costs. The study aims to confirm: * That ICR is associated with better outcome…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Trinity Health Ann Arbor, Ypsilanti, Michigan

    Locations

    3 in total

    Run by

    Pritikin ICR

    See if you can join NCT06424119 on ClinicalTrials.gov

23. Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors

    The goal of our pragmatic clinical trial is to compare how well three different strategies might do to reduce risk factors for cardiovascular disease in patients experiencing health disparities. The three different strategies are: 1) text messages, 2) interactive chatbot messages, and 3) chatbot me…

    Stage

    Not phased

    Ages

    18 to 89

    Site

    Denver Health, Denver, Colorado

    Locations

    3 in total

    Run by

    University of Colorado, Denver

    See if you can join NCT06324981 on ClinicalTrials.gov

24. Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"

    This is an international prospective, multicentre, unblinded, randomised-controlled trial. The primary aim is to assess a targeted screening strategy to detect undiagnosed heart failure in high-risk patients.

    Stage

    Not phased

    Ages

    40 and older

    Site

    University of Glasgow, Glasgow, Scotland

    Locations

    7 in total

    Run by

    NHS Greater Glasgow and Clyde

    See if you can join NCT05919342 on ClinicalTrials.gov

25. Phase I Human Analytics (HALO) Study

    Discover, optimize, standardize, and validate clinical-trial measures and biomarkers used to diagnose and differentiate cardiovascular, oncologic, neurologic, and other diseases and disorders. Specifically, our research study endeavors to improve disease and disorder diagnosis to the earliest clini…

    Stage

    Not phased

    Ages

    45 to 90

    Site

    Desert Medical Imaging, Indian Wells, California

    Run by

    HALO Diagnostics

    See if you can join NCT05423860 on ClinicalTrials.gov