Stroke Clinical Trials

216 studies are recruiting for stroke in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 4

1. Efficacy of Tele-CPASS Compared to In-person CPASS Therapy for Upper Extremity Motor Recovery

   This study evaluates whether a home-based telerehabilitation program (tele-CPASS) is as effective as an in-person rehabilitation program (CPASS) for improving arm and hand function after stroke. Stroke often leads to long-term difficulty using the affected arm in daily activities, and access to in-…

   Stage

   Not phased

   Ages

   21 and older

   Site

   Rehabilitation Sciences Complex, University of Texas at El Paso, 3333 N Mesa St, El Paso, TX 79902, El Paso, Texas

   Locations

   3 in total

   Run by

   University of Texas, El Paso

   See if you can join NCT07661849 on ClinicalTrials.gov

2. Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke

   The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes. The main questions it aims to answer are: 1. What regions of the brain's…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06458153 on ClinicalTrials.gov

3. Emotional Recovery Post-Stroke

   The purpose of this study is to evaluate whether adding an emotional wellness component to occupational therapy (OT) and/or speech therapy (ST) telerehabilitation improves overall emotional well-being and activity participation for people with stroke.

   Stage

   Not phased

   Ages

   21 and older

   Site

   Medical University of South Carolina, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT06782321 on ClinicalTrials.gov

4. Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia

   The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with modified Constraint Induced Language Therapy (mCILT) is an effective treatment for aphasia when delivered in the subacute stage after stroke. The main questions this study aims to answer are: 1.…

   Stage

   Phase 2

   Ages

   18 to 85

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT06968663 on ClinicalTrials.gov

5. Tracking a Tactile Signal Along the Nervous System

   Quantify the flow of a tactile signal from the stimulus at the finger at the peripheral nervous system (PNS), to the central nervous system (CNS), and to cognitive perception at the brain in young adults (Aim 1) and individuals with and without stroke (Aim 2).

   Stage

   Not phased

   Ages

   18 and older

   Site

   Virginia Tech, Blacksburg, Virginia

   Run by

   Virginia Polytechnic Institute and State University

   See if you can join NCT06231810 on ClinicalTrials.gov

6. Tele-CE in Severe Stroke

   The goal of this clinical trial is to determine the effects of home-based cross-education on lower limb neuroplasticity in severe stroke. The main questions the investigators aim to answer are: * What are the effects of home-based cross-education on lower limb neuroplasticity? * What are the effect…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Brain Plasticity Lab, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT07652970 on ClinicalTrials.gov

7. Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms

   Patients harboring dolichoectactic vertebrobasilar (DVB) aneurysms are at risk of suffering SAH, ischemic stroke, and/or brainstem compression and many patients are not offered invasive treatment due to the futility of existing surgical methods. Consequently, there is demand for development of medi…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   UCSF Medical Center, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT02638701 on ClinicalTrials.gov

8. Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis

   An observational study to determine if individuals with increased platelet FcyRIIa will have a higher risk of ischemic events.

   Stage

   Not phased

   Ages

   30 and older

   Site

   Ronald Reagan UCLA Medical Center, Los Angeles, California

   Run by

   University of California, Los Angeles

   See if you can join NCT05518305 on ClinicalTrials.gov

9. Impact of VNS With Rehab on Gait Post-Stroke

   This is a prospective, double-blinded, randomized controlled study to evaluate the impact of Vagus Nerve Stimulation (VNS) therapy on lower limb function.

   Stage

   Not phased

   Ages

   22 to 80

   Site

   University at Buffalo Neurosurgery, Buffalo, New York

   Run by

   State University of New York at Buffalo

   See if you can join NCT07643337 on ClinicalTrials.gov

10. MINT Conditioning to Improve Gait

    This study will test the ability of myoelectric interface for neurorehabilitation (MINT) training to improve walking function.

    Stage

    Not phased

    Ages

    18 to 85

    Site

    Northwestern University, Chicago, Illinois

    Locations

    2 in total

    Run by

    Northwestern University

    See if you can join NCT07041775 on ClinicalTrials.gov

11. Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition

    This is a study using magnetoencephalography (MEG) to look at recovery in those with minor stroke. The investigators know that these individuals report difficulties in attention, concentration, multi-tasking, energy level, and processing speed that appear to be independent of lesion size or locatio…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Johns Hopkins Bayview Medical Center, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT04188522 on ClinicalTrials.gov

12. Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways

    The goal of this study is to assess cervical (neck) reflexes by intra-operatively stimulating the neck nerve roots to evoke motor responses through their connections to spinal motoneurons. This data is critical to reveal changes to the spinal sensory modulating circuitry in neurological disorders l…

    Stage

    Not phased

    Ages

    21 to 75

    Site

    University of Pittsburgh, Pittsburgh, Pennsylvania

    Run by

    Peter C. Gerszten, MD

    See if you can join NCT07401186 on ClinicalTrials.gov

13. Fall Risk Intervention for Stroke

    After stroke, falling is a common problem. Falls can lead to injury, as well as fear of future falls. It is important to try to prevent falls from happening after stroke. To goal of this study is to test a new treatment to try to prevent falls after stroke. The people in the study will be patients …

    Stage

    Not phased

    Ages

    45 to 85

    Site

    Spaulding Rehabilitation Hospital, Boston, Massachusetts

    Run by

    MGH Institute of Health Professions

    See if you can join NCT07349030 on ClinicalTrials.gov

14. Brain Connections for Arm Movement After Stroke

    The purpose of this study is to use Transcranial Magnetic Stimulation (TMS) while subjects are making reaching movements in a robotic arm device in order to discover how different brain areas control movement before and after stroke and when these brain areas are most sensitive to TMS.

    Stage

    Not phased

    Ages

    45 to 90

    Site

    VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh, Pennsylvania

    Run by

    VA Office of Research and Development

    See if you can join NCT04286516 on ClinicalTrials.gov

15. Recovery From Post-Stroke Aphasia With rTMS Targeting Left or Right Anterior Temporal Lobe

    This project aims to tailor repetitive Transcranial Magnetic Stimulation (rTMS) target to the clinical profile of post-stroke aphasia, specifically focusing on lexicosemantic impairments, to enhance recovery. Functional Magnetic Resonance Imaging (fMRI) will provide critical insights into the effec…

    Stage

    Not phased

    Ages

    18 and older

    Site

    McCausland Center, Columbia, South Carolina

    Run by

    University of South Carolina

    See if you can join NCT07608588 on ClinicalTrials.gov

16. Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke

    This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended tra…

    Stage

    Not phased

    Ages

    21 to 100

    Site

    Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT04312269 on ClinicalTrials.gov

17. Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

    62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analys…

    Stage

    Not phased

    Ages

    25 to 85

    Site

    University of New Mexico Center for Brain Recovery and Repair, Albuquerque, New Mexico

    Run by

    University of New Mexico

    See if you can join NCT04432883 on ClinicalTrials.gov

18. International Care Bundle Evaluation in Cerebral Hemorrhage Research

    Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. Despite this, intensive care and neur…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    The University of Oklahoma Health, Oklahoma City, Oklahoma

    Locations

    54 in total

    Run by

    Region Skane

    See if you can join NCT06429332 on ClinicalTrials.gov

19. The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.

    The study is about using a brain stimulation technique called rTMS (Repetitive Transcranial Magnetic Stimulation) to help improve hand muscles in people who had a stroke. Researchers want to understand how this device can help stroke patients use their hands better.

    Stage

    Not phased

    Ages

    21 and older

    Site

    Duke University Medical Center, Durham, North Carolina

    Run by

    Duke University

    See if you can join NCT06765642 on ClinicalTrials.gov

20. Sensory Feedback and Hand Motor Adaptation

    The following experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform hand movements in the virtual reality environment using a head-mounted display. Quest's onboard cameras allow real-time tracking of hand motion, estimating joint angles of the …

    Stage

    EARLY_Phase 1

    Ages

    20 to 70

    Site

    Catholic University of America, Washington D.C., District of Columbia

    Run by

    The Catholic University of America

    See if you can join NCT07598695 on ClinicalTrials.gov

21. Exercise and Motor Learning After Stroke (Study #3)

    Subjects with chronic stroke (> 6 months post-stroke) will learn a new walking pattern through distorted visual feedback. Retention of the pattern will be tested without visual feedback immediately after learning and 24 hours later. Subjects will be randomly assigned to the control group or the exe…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    University of Delaware, Newark, Delaware

    Run by

    University of Delaware

    See if you can join NCT03726047 on ClinicalTrials.gov

22. Spatial-Motor Stroke-Rehab Study

    The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.

    Stage

    Not phased

    Ages

    18 to 90

    Site

    Emory Rehabilitation Hospital, Atlanta, Georgia

    Locations

    3 in total

    Run by

    Emory University

    See if you can join NCT06053320 on ClinicalTrials.gov

23. Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors

    The goal of this study is to test if Savvy, a multimodal intervention (consisting of psychological exercises, a weekly pill organizer, and a text message reminder system) can improve medication adherence in stroke survivors. The main questions it aims to answer are: * Can the Savvy tool improve med…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Massachusetts General Hospital

    See if you can join NCT07414732 on ClinicalTrials.gov

24. Weight Loss and ExeRcise for Post-stroke Veterans

    Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise tr…

    Stage

    Not phased

    Ages

    40 to 80

    Site

    Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina

    Run by

    VA Office of Research and Development

    See if you can join NCT06322030 on ClinicalTrials.gov

25. Strategy Training for Optimizing Attention for Individuals With Spatial Neglect

    It is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect). Individuals with neglect have difficulty paying attention to one side of their body or one side of the environment and therefore experience difficulty performing daily ac…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Pittsburgh, Pittsburgh, Pennsylvania

    Run by

    University of Pittsburgh

    See if you can join NCT07331896 on ClinicalTrials.gov