Stroke Clinical Trials in Charleston, South Carolina

18 studies are recruiting for stroke in Charleston, South Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue

    This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's abili…

    Stage
    Phase 2
    Ages
    34 to 80
    Site
    Ralph H. Johnson VA Medical Center, Charleston, South Carolina
    Locations
    2 in total
    Run by
    VA Office of Research and Development
  2. Telerehabilitation In The Home After Stroke

    The purpose of this research study is to evaluate whether telerehabilitation targeting arm movement, when added to usual care, improves arm function and reduces global disability after stroke, compared to usual care alone. Patients with arm weakness due to stroke that happened in the past 90-150 da…

    Stage
    Not phased
    Ages
    18 to 80
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Locations
    27 in total
    Run by
    University of California, Los Angeles
  3. Escitalopram and Language Intervention for Subacute Aphasia

    In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming untrained pictures and describing pictures, in individuals with aphasia in the acute and subacute pos…

    Stage
    Phase 2
    Ages
    18 to 99
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Locations
    3 in total
    Run by
    Johns Hopkins University
  4. Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

    VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, tra…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Medical University of South Carolina (MUSC), Charleston, South Carolina
    Locations
    45 in total
    Run by
    Yale University
  5. Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking

    Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in individuals with post-stroke depression (PSD). Investigators propose …

    Stage
    Not phased
    Ages
    21 and older
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Locations
    2 in total
    Run by
    Medical University of South Carolina
  6. GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

    This study will assess the safety and effectiveness of GORE® CARDIOFORM Septal Occluder in a post approval setting and evaluate the quality of operator education and training and transferability of trial experience to a post-market setting.

    Stage
    Not phased
    Ages
    18 to 70
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Locations
    45 in total
    Run by
    W.L.Gore & Associates
  7. Pilot/Pivotal Study of DBS+Rehab After Stroke

    The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke.

    Stage
    Not phased
    Ages
    21 and older
    Site
    Medical University of South Carolina (MUSC), Charleston, South Carolina
    Locations
    10 in total
    Run by
    Enspire DBS Therapy, Inc.
  8. Accelerated rTMS vs. Sham for Stroke Apathy

    Apathy is a common set of symptoms seen in many people following a stroke. Apathy occurs when a person has lost motivation, becomes withdrawn, and stops doing things that used to be important to them. Apathy has a large negative impact on a person's quality of life, and can also have a large impact…

    Stage
    Phase 1
    Ages
    40 and older
    Site
    Medical University of South Carolina Brain Stimulation Lab, Charleston, South Carolina
    Run by
    Medical University of South Carolina
  9. Emotional Recovery Post-Stroke

    The purpose of this study is to evaluate whether adding an emotional wellness component to occupational therapy (OT) and/or speech therapy (ST) telerehabilitation improves overall emotional well-being and activity participation for people with stroke.

    Stage
    Not phased
    Ages
    21 and older
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Run by
    Medical University of South Carolina
  10. Weight Loss and ExeRcise for Post-stroke Veterans

    Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise tr…

    Stage
    Not phased
    Ages
    40 to 80
    Site
    Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina
    Run by
    VA Office of Research and Development
  11. Exoskeleton for Balance

    Many people who have experienced a stroke have deficits in their walking balance. The long-term goal of this research is to develop an exoskeleton that can effectively improve walking balance, thus improving functional mobility.

    Stage
    Not phased
    Ages
    21 and older
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Run by
    Medical University of South Carolina
  12. EMPOWER: Effects of Weight Loss and Exercise Post-stroke

    The prevalence of obesity among U.S. adults is ~40% and is projected to climb. It is well documented that obesity is associated with increased levels of disability as well as risk for numerous adverse health-related outcomes; including occurrence of stroke and all-cause mortality. Obesity is highly…

    Stage
    Not phased
    Ages
    35 to 85
    Site
    College of Health Professions, Charleston, South Carolina
    Run by
    Medical University of South Carolina
  13. Exercise Primed Stroke Rehabilitation

    Stroke is a leading cause of disability in the U.S. and many Veteran stroke survivors live with severe disability. Despite recent advances in rehabilitation treatments many stroke survivors have persistent physical and mental difficulties such as reduced physical and cognitive function and depressi…

    Stage
    EARLY_Phase 1
    Ages
    50 to 90
    Site
    Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina
    Run by
    VA Office of Research and Development
  14. Multisensory Augmentation for Post-stroke Standing Balance

    Many individuals who experience a stroke have problems with their balance. In part, these balance problems may be due to sensory issues. This study will test whether sensory augmentation has the potential to improve post-stroke balance. Sensory augmentation is a method by which non-invasive vibrati…

    Stage
    EARLY_Phase 1
    Ages
    21 and older
    Site
    Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina
    Run by
    VA Office of Research and Development
  15. Stroke Thrombectomy and Aneurysm Registry

    This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood ves…

    Stage
    Not phased
    Ages
    1 to 120
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Locations
    63 in total
    Run by
    Medical University of South Carolina
  16. Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

    Durable left ventricular assist devices (dLVAD) have been increasingly utilized since the mid to late 1990s, with an uptick of utility starting in 2010 following expanded indications for therapy to not only include a bridge to transplantation strategy, but also for those individuals who suffer from…

    Stage
    Not phased
    Ages
    18 to 100
    Site
    MUSC, Charleston, South Carolina
    Locations
    7 in total
    Run by
    International Consortium of Circulatory Assist Clinicians
  17. Physical Capacity Building for Chronic Stroke

    Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery. Investigators believe that individuals who have had a stroke need to be treated similarly. Investigators will study the e…

    Stage
    Not phased
    Ages
    18 to 80
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Run by
    Medical University of South Carolina
  18. EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke

    The purpose of this study is to develop and test if upper limb task practice and muscle activity training improve upper limb function in stroke survivors. Participants will be asked to come to the laboratory 23 times (approximately 3 times a week) over 2.5 months to receive upper limb task practice…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina
    Run by
    VA Office of Research and Development

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.