Stroke Clinical Trials in Philadelphia, Pennsylvania

13 studies are recruiting for stroke in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

   This is a Phase 2/3 study evaluating the safety and efficacy of DM199 (rinvecalinase alfa) in treating participants with moderate stroke severity, who present within 24 hours of Acute Ischemic Stroke (AIS) onset due to small and medium vessel occlusions. This study focuses on participants with limi…

   Stage

   Phase 2

   Ages

   18 to 90

   Site

   The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   86 in total

   Run by

   DiaMedica Therapeutics Inc

   See if you can join NCT05065216 on ClinicalTrials.gov

2. CoMind Early Feasibility Study

   The purpose of this research, which has been determined as non-significant risk by the central IRB overseeing the study, is to obtain information to help further develop a machine (a medical device) to measure the pressure around the brain from the outside (this pressure is called intracranial pres…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pennsylvania Hospital, Philadelphia, Pennsylvania

   Locations

   16 in total

   Run by

   CoMind Technologies Limited

   See if you can join NCT06368648 on ClinicalTrials.gov

3. tACS to Enhance Language Abilities

   The goal of this study is to see if transcranial alternating current stimulation (tACS) can be used to enhance language abilities in people with post-stroke aphasia. Participants will receive real and sham tACS in conjunction with various language tests. Researchers will compare the post-stroke aph…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT06092814 on ClinicalTrials.gov

4. Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

   VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, tra…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Pennsylvania Hospital, Philadelphia, Pennsylvania

   Locations

   45 in total

   Run by

   Yale University

   See if you can join NCT05338697 on ClinicalTrials.gov

5. Pilot/Pivotal Study of DBS+Rehab After Stroke

   The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke.

   Stage

   Not phased

   Ages

   21 and older

   Site

   Thomas Jefferson University, Philadelphia, Pennsylvania

   Locations

   10 in total

   Run by

   Enspire DBS Therapy, Inc.

   See if you can join NCT05701280 on ClinicalTrials.gov

6. Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

   The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated c…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   106 in total

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT04045665 on ClinicalTrials.gov

7. Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia

   The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with modified Constraint Induced Language Therapy (mCILT) is an effective treatment for aphasia when delivered in the subacute stage after stroke. The main questions this study aims to answer are: 1.…

   Stage

   Phase 2

   Ages

   18 to 85

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT06968663 on ClinicalTrials.gov

8. Neuralert Stroke Monitor Trial

   The Neuralert monitoring system, a non-invasive device worn on each wrist, is designed to provide continuous monitoring and expedited recognition of stroke by identifying asymmetry in the extremities, facilitating patient treatment and improving outcomes. This study is designed to evaluate the safe…

   Stage

   Not phased

   Ages

   22 and older

   Site

   Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   Neuralert Technologies LLC

   See if you can join NCT07362303 on ClinicalTrials.gov

9. Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)

   This interventional trial will compare a novel prehospital stroke transport algorithm (OPUS-i) to a traditional prehospital stroke transport algorithm to improve outcomes in rural stroke patients by determining the effect of implementing a data-driven prehospital stroke algorithm on time to and end…

   Stage

   Not phased

   Ages

   18 and older

   Site

   3401 N Broad street, Philadelphia, Pennsylvania

   Locations

   2 in total

   Run by

   Temple University

   See if you can join NCT06530693 on ClinicalTrials.gov

10. Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

    The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with Speech-Language Therapy (SLT) is an effective treatment for mild aphasia in persons with chronic stroke. The main questions this study aims to answer are: 1. Can TMS combined with SLT improve co…

    Stage

    Phase 2

    Ages

    40 to 85

    Site

    University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT06842745 on ClinicalTrials.gov

11. The Neuralert Stroke Monitor Pilot Trial

    This trial aims to demonstrate that the Neuralert Monitoring System will detect strokes before they would be identified by current standard of care. Each patient will be monitored for up to five days, depending on device connectivity or battery duration. Each monitoring session will consist of wear…

    Stage

    Not phased

    Ages

    22 and older

    Site

    Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    Neuralert Technologies LLC

    See if you can join NCT06368193 on ClinicalTrials.gov

12. Stroke Thrombectomy and Aneurysm Registry

    This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood ves…

    Stage

    Not phased

    Ages

    1 to 120

    Site

    Thomas Jefferson University, Philadelphia, Pennsylvania

    Locations

    63 in total

    Run by

    Medical University of South Carolina

    See if you can join NCT04994756 on ClinicalTrials.gov

13. Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

    This prospective, randomized study aims to comprehensively evaluate the impact of cranioplasty timing on postoperative complications and long-term functional outcomes following decompressive hemicraniectomy (DHC). The primary endpoint focuses on comparing the rates of various postoperative complica…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Thomas Jefferson University Hospitals, Philadelphia, Pennsylvania

    Run by

    Thomas Jefferson University

    See if you can join NCT06632587 on ClinicalTrials.gov