Stroke Clinical Trials in Boston, Massachusetts

20 studies are recruiting for stroke in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Telerehabilitation In The Home After Stroke

    The purpose of this research study is to evaluate whether telerehabilitation targeting arm movement, when added to usual care, improves arm function and reduces global disability after stroke, compared to usual care alone. Patients with arm weakness due to stroke that happened in the past 90-150 da…

    Stage
    Not phased
    Ages
    18 to 80
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    27 in total
    Run by
    University of California, Los Angeles

    See if you can join NCT06682429 on ClinicalTrials.gov

  2. Treatment With Endovascular Intervention for STroke Patients With Existing Disability

    TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Boston Medical Center, Boston, Massachusetts
    Locations
    35 in total
    Run by
    University of Cincinnati

    See if you can join NCT05911568 on ClinicalTrials.gov

  3. Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

    VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, tra…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    45 in total
    Run by
    Yale University

    See if you can join NCT05338697 on ClinicalTrials.gov

  4. Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation

    Patients with atrial fibrillation (AF) who have had a prior stroke are at very high risk of recurrent ischemic stroke. About 40% of these strokes are due to large emboli which result in large cerebral vessel occlusion (LVO). This randomized control trial aims to address this unmet need by testing w…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Boston University Medical Center, Boston, Massachusetts
    Locations
    21 in total
    Run by
    Javelin Medical

    See if you can join NCT05723926 on ClinicalTrials.gov

  5. GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

    This study will assess the safety and effectiveness of GORE® CARDIOFORM Septal Occluder in a post approval setting and evaluate the quality of operator education and training and transferability of trial experience to a post-market setting.

    Stage
    Not phased
    Ages
    18 to 70
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    45 in total
    Run by
    W.L.Gore & Associates

    See if you can join NCT03821129 on ClinicalTrials.gov

  6. Pilot/Pivotal Study of DBS+Rehab After Stroke

    The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke.

    Stage
    Not phased
    Ages
    21 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    10 in total
    Run by
    Enspire DBS Therapy, Inc.

    See if you can join NCT05701280 on ClinicalTrials.gov

  7. An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation

    The aim of this phase is to examine the feasibility and acceptability of the Augmented Reality (AR)-based and electroencephalography (EEG)-based neglect detection and rehabilitation tool.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Northeastern University, Boston, Massachusetts
    Locations
    2 in total
    Run by
    University of Pittsburgh

    See if you can join NCT04187131 on ClinicalTrials.gov

  8. Genetic and Environmental Risk Factors for Hemorrhagic Stroke

    The purpose of this study is to find risk factors for hemorrhagic stroke.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    7 in total
    Run by
    State University of New York at Buffalo

    See if you can join NCT00682695 on ClinicalTrials.gov

  9. Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

    The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated c…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    106 in total
    Run by
    Icahn School of Medicine at Mount Sinai

    See if you can join NCT04045665 on ClinicalTrials.gov

  10. Fall Risk Intervention for Stroke

    After stroke, falling is a common problem. Falls can lead to injury, as well as fear of future falls. It is important to try to prevent falls from happening after stroke. To goal of this study is to test a new treatment to try to prevent falls after stroke. The people in the study will be patients …

    Stage
    Not phased
    Ages
    45 to 85
    Site
    Spaulding Rehabilitation Hospital, Boston, Massachusetts
    Run by
    MGH Institute of Health Professions

    See if you can join NCT07349030 on ClinicalTrials.gov

  11. Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors

    The goal of this study is to test if Savvy, a multimodal intervention (consisting of psychological exercises, a weekly pill organizer, and a text message reminder system) can improve medication adherence in stroke survivors. The main questions it aims to answer are: * Can the Savvy tool improve med…

    Stage
    Not phased
    Ages
    18 to 99
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    2 in total
    Run by
    Massachusetts General Hospital

    See if you can join NCT07414732 on ClinicalTrials.gov

  12. Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors

    The goal of this study is to: 1. Assess the usability of the SynPhNe device in a home environment. 2. Evaluate the efficacy of the SynPhNe home use device to improve motor hand function in chronic stroke subjects as compared to standard care alone.

    Stage
    Not phased
    Ages
    21 to 80
    Site
    Spaulding Rehabilitation Hospital, Boston, Massachusetts
    Run by
    Spaulding Rehabilitation Hospital

    See if you can join NCT02896348 on ClinicalTrials.gov

  13. Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

    The Connect-One Study is an early feasibility study to obtain preliminary device safety information for the Connexus Brain-Computer Interface (BCI). The Connexus BCI is intended to be used as: (1) an assistive communication device to decode imagined language correlates and speech for patients with …

    Stage
    Not phased
    Ages
    22 to 75
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    3 in total
    Run by
    Paradromics

    See if you can join NCT07357428 on ClinicalTrials.gov

  14. Pulmonary Embolism and Right-to-Left Shunts

    Every fetus has a small hole in their heart, called a foramen ovale when they are developing in the womb. For most people this hole closes shortly after birth, but it doesn't close completely in 1 out of every 4 people. This is called a "patent" foramen ovale, or PFO. In people with a PFO it is pos…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Tufts Medical Center, Boston, Massachusetts
    Run by
    Tufts Medical Center

    See if you can join NCT07519876 on ClinicalTrials.gov

  15. Substrates for Post-Stroke Arm Rehabilitation

    Difficulty moving the arm is very common and a major cause of disability after stroke. Although rehabilitation therapies (i.e., occupational and physical therapy) are the most common treatments used to improve arm motor function, it remains unknown how therapy actually changes brain pathways after …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Laboratory for Translational Neurorecovery, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT06998485 on ClinicalTrials.gov

  16. Improving Visual Field Deficits With Noninvasive Brain Stimulation

    This is a randomized, pilot interventional study in participants with visual field deficit (VFD) caused by cortical lesion. Damage to the primary visual cortex (V1) causes a contra-lesional, homonymous loss of conscious vision termed hemianopsia, the loss of one half of the visual field. The goal o…

    Stage
    Not phased
    Ages
    18 to 80
    Site
    Beth Israel Deaconess Medical Center, Boston, Massachusetts
    Run by
    Beth Israel Deaconess Medical Center

    See if you can join NCT05085210 on ClinicalTrials.gov

  17. Stroke Thrombectomy and Aneurysm Registry

    This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood ves…

    Stage
    Not phased
    Ages
    1 to 120
    Site
    Beth Israel Deaconess Medical Center, Boston, Massachusetts
    Locations
    63 in total
    Run by
    Medical University of South Carolina

    See if you can join NCT04994756 on ClinicalTrials.gov

  18. Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors

    The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in chronic stroke survivors. The Intervention group will use StrokeWear system in combination to a motor and behavioral home intervention …

    Stage
    Phase 2
    Ages
    18 to 85
    Site
    Spaulding Rehabilitation Hospital Boston, Boston, Massachusetts
    Run by
    Spaulding Rehabilitation Hospital

    See if you can join NCT05626894 on ClinicalTrials.gov

  19. A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Subacute Stroke Survivors

    The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in subacute stroke survivors. The Intervention group will use StrokeWear system in combination to a motor and behavioral home intervention…

    Stage
    Not phased
    Ages
    18 to 85
    Site
    Spaulding Rehabilitation Hospital, Boston, Massachusetts
    Run by
    Spaulding Rehabilitation Hospital

    See if you can join NCT06797154 on ClinicalTrials.gov

  20. BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement

    The investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health. The goal of this study is to compare two new ways of lowering blood pressure. The first way is to help people check their b…

    Stage
    Not phased
    Ages
    35 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT07091851 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.