Cancer Clinical Trials

252 studies are recruiting for cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 8

1. Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

   The purpose of this study is to determine the effectiveness of a digital health program called AYA STEPS, which is designed to help adolescent and young adult (AYA) cancer survivors manage symptoms and engage in recommended follow-up care.

   Stage

   Not phased

   Ages

   18 to 39

   Site

   Duke Cancer Institute, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06371768 on ClinicalTrials.gov

2. Effectiveness of Central Oncology Navigation and the Use of an ORN

   This health services interventional study investigates the effectiveness of central oncology navigation (SOC ) alone and central oncology navigation with a new role called an "oncology research navigator (ORN)" who is embedded in central oncology navigation cancer care delivery. This study will exa…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

   Run by

   UNC Lineberger Comprehensive Cancer Center

   See if you can join NCT06618274 on ClinicalTrials.gov

3. F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors)

   The investigators will conduct a 2-arm 6-month randomized clinical controlled trial to evaluate the effectiveness of an oral Telehealth Intervention (THI) in preventing cancer-related oral complications, improving oral health maintenance and oral health related quality of life, and reducing systemi…

   Stage

   Not phased

   Ages

   25 to 75

   Site

   Georgetown Lombardi Office of Minority Health, Washington D.C., District of Columbia

   Run by

   Georgetown University

   See if you can join NCT06315855 on ClinicalTrials.gov

4. Caris Biorepository Research Protocol

   The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients. The Caris Biorepository is a repository of prospectively collecte…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of South Alabama, Mobile, Alabama

   Locations

   38 in total

   Run by

   Caris Science, Inc.

   See if you can join NCT01499394 on ClinicalTrials.gov

5. A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

   The goal of this clinical trial is to test JMT108, a type of drug called a bispecific antibody in adult patients with locally advanced or metastatic solid tumors. The main questions it aims to answer are: * To assess the safety and tolerability of JMT108 at increasing doses and determine the dose a…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Carolina BioOncology Institute, Huntersville, North Carolina

   Locations

   3 in total

   Run by

   Conjupro Biotherapeutics, Inc.

   See if you can join NCT07317505 on ClinicalTrials.gov

6. eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

   This randomized non-inferiority study will use a 2x2 design where traditional standard-of-care pre-test (visit 1) and post-test (visit 2: disclosure) counseling delivered by a genetic counselor are replaced with a self-directed web-based eHealth intervention to provide critical data to inform optim…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   Abramson Cancer Center at Penn Medicine

   See if you can join NCT05427240 on ClinicalTrials.gov

7. A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

   The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer and their caregiving partners.

   Stage

   Not phased

   Ages

   25 to 39

   Site

   Massachusetts General Hospital Cancer Center, Boston, Massachusetts

   Locations

   4 in total

   Run by

   Massachusetts General Hospital

   See if you can join NCT06172907 on ClinicalTrials.gov

8. Autoimmunity After Checkpoint Blockade

   The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity. Specifically, we wish to understand the genetics and immune system features that cause a subset of cancer patients treated with checkpoint …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pennsylvania - Abramson Cancer Center, Philadelphia, Pennsylvania

   Run by

   Abramson Cancer Center at Penn Medicine

   See if you can join NCT04119713 on ClinicalTrials.gov

9. Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

   Our team has developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression. This tool includes one psychoeducation component and four components that are based on evidence-based interventions for depression. The goal of this stud…

   Stage

   Not phased

   Ages

   15 to 39

   Site

   East Carolina University, Greenville, North Carolina

   Locations

   2 in total

   Run by

   East Carolina University

   See if you can join NCT07173205 on ClinicalTrials.gov

10. Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)

    While chronic cancer pain affecting as many as 75% of patients is typically addressed using pharmacologic interventions, experts and patients alike support maximizing any relevant non-pharmacologic interventions as well, such as cognitive behavioral therapy. Virtual reality, a novel technology that…

    Stage

    Not phased

    Ages

    18 and older

    Site

    MedStar Health Research Institute, Washington D.C., District of Columbia

    Locations

    2 in total

    Run by

    Medstar Health Research Institute

    See if you can join NCT07318519 on ClinicalTrials.gov

11. Immune Reconstitution in Stem Cell Transplant Recipients

    This specimen collection lab protocol will allow the investigators to prospectively study immune reconstitution in patients being treated for hematologic disorders and immune factors affecting graft versus host disease in stem-cell transplant (SCT) patients.

    Stage

    Not phased

    Ages

    18 to 75

    Site

    University of Miami, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT02129543 on ClinicalTrials.gov

12. Digital Phenotyping for Psychosocial Screening in Adolescents and Young Adults With Cancer

    The overall goal of the proposed study is to use digital phenotyping to identify and triage at-risk patients and accelerate access to critical mental health services.

    Stage

    Not phased

    Ages

    10 to 25

    Site

    Stanford University, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT07220343 on ClinicalTrials.gov

13. Digital Intervention for Symptom Management in Cancer and Opioid Sparing Using Virtual Reality (DISCOVR) Study

    Patients living with cancer commonly have chronic pain due to the disease or to cancer treatments. Virtual reality, a new technology that immerses the user in pleasant, diverting, and exciting virtual environments, may lower chronic cancer pain to improve quality of life and complement need for pai…

    Stage

    Not phased

    Ages

    18 and older

    Site

    MedStar Georgetown Cancer Institute at MedStar Washington Hospital Center, Washington D.C., District of Columbia

    Run by

    Medstar Health Research Institute

    See if you can join NCT07228377 on ClinicalTrials.gov

14. The Gut Microbiome and Immunotherapy Response in Solid Cancers

    The aim of this study is characterize the gastrointestinal microbiomes of patient with solid cancer undergoing standard of care treatment with programmed cell death protein 1 (PD-1) /programmed cell death ligand (PD-L1) blockade.

    Stage

    Not phased

    Ages

    35 to 75

    Site

    University of Texas Medical Branch, Galveston, Texas

    Run by

    The University of Texas Medical Branch, Galveston

    See if you can join NCT06050733 on ClinicalTrials.gov

15. Radiotherapy Patient Education With Virtual Reality

    The purpose of this research study is to investigate the impact of virtual reality experiences on individuals undergoing radiotherapy, aiming to assess whether this immersive technology can reduce anxiety and enhance patient overall treatment satisfaction. By comparing different virtual reality tec…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Miami, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT06506435 on ClinicalTrials.gov

16. Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies

    This phase III clinical trial will evaluate the impact on survival of adding chaplain-provided spiritual care or psychotherapy/meditation to standard-of-care (SOC) and palliative measures, plus chemotherapy if recommended, and comparing it with SOC and palliative measures, plus chemotherapy if reco…

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Houston Methodist Neal Cancer Center, Houston, Texas

    Run by

    The Methodist Hospital Research Institute

    See if you can join NCT07290491 on ClinicalTrials.gov

17. Correlates of CRCI and Gut Microbiome Dysbiosis; a Pilot Study

    The aim of this study is to characterize the microbiome and assess fatigue and cognition of patients with cancer undergoing standard of care treatment.

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Texas Medical Branch, Galveston, Texas

    Run by

    The University of Texas Medical Branch, Galveston

    See if you can join NCT06098404 on ClinicalTrials.gov

18. Immune Profiling for Cancer Immunotherapy Response

    In patients clinically treated with FDA-approved immunotherapy the investigators will assess the predictive value of pre- and on-treatment 1) immune-methylation profiling across cancer types, and 2) immune-methylation profiling and cytokine profiling within cancer types.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT06116032 on ClinicalTrials.gov

19. Discovering New Genetic Markers in Adults and Children Who May Be At Risk for Hereditary Forms of Cancer

    This study is being done to attempt to identify genetic mutations or other gene-based variations in adults and children who have cancer, or are likely to develop an inherited form of cancer, and potentially reduce their risk for cancer or treat the cancer earlier.

    Stage

    Not phased

    Ages

    Any age

    Site

    Memorial Sloan Kettering Basking Ridge (Consent only), Basking Ridge, New Jersey

    Locations

    7 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT03922893 on ClinicalTrials.gov

20. Cryopreservation of Ovarian Tissue

    The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.

    Stage

    Not phased

    Ages

    Up to 45

    Site

    Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York, New York

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT01558544 on ClinicalTrials.gov

21. Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer

    The purpose of this study is to determine if analysis of DNA and protein material found in urine will be useful in the detection of urothelial cancer of the bladder and kidney. This analysis may be helpful to determine if how a particular cancer will act regarding remission and recurrence

    Stage

    Not phased

    Ages

    18 and older

    Site

    Lahey Clinic, Inc., Burlington, Massachusetts

    Run by

    Lahey Clinic

    See if you can join NCT00872495 on ClinicalTrials.gov

22. Testicular Tissue Cryopreservation in Children

    This protocol is being designed to offer testicular tissue cryopreservation to male pediatric patients (0-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may cause loss of reproductive potential.

    Stage

    Not phased

    Ages

    0 to 17

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT02872532 on ClinicalTrials.gov

23. Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients

    The purpose of this study is to evaluate the effectiveness of a multi-component intervention to improve young cancer survivors' engagement in goal-concordant oncofertility care, concurrently with observing and gathering information on how the intervention is implemented. The investigators hypothesi…

    Stage

    Phase 3

    Ages

    0 to 50

    Site

    City of Hope, Duarte, California

    Locations

    4 in total

    Run by

    University of California, San Diego

    See if you can join NCT05443737 on ClinicalTrials.gov

24. Enhancing Motivation to Quit Smoking Via Self-Help Intervention Targeted to Cancer Type

    The purpose of this research study is assess feasibility and acceptability of a recently developed brief self-help intervention targeted by cancer type to increase motivation to quit smoking.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Huntsman Cancer Institute, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT06484179 on ClinicalTrials.gov

25. Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

    Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve…

    Stage

    Phase 2

    Ages

    2 to 99

    Site

    University of California, San Francisco, San Francisco, California

    Locations

    5 in total

    Run by

    Children's Hospital of Philadelphia

    See if you can join NCT05783323 on ClinicalTrials.gov