Cancer Clinical Trials

252 studies are recruiting for cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 7

1. Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)

   The purpose of the study is to understand patient interest in telehealth and digital tools for pre-test genetic education and/or disclosure of genetic test results. Participants will receive telehealth genetic counseling in the home and may be offered various digital tools to help with the counseli…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   Abramson Cancer Center at Penn Medicine

   See if you can join NCT07471958 on ClinicalTrials.gov

2. Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

   The goal of this research study is to measure changes in patients' quality of life after surgeries that affect the facial nerve, including nerve transfer as treatment for facial paralysis.

   Stage

   Not phased

   Ages

   18 and older

   Site

   The University of Texas M. D. Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT06667427 on ClinicalTrials.gov

3. Prospective Study to Assess a Diagnostic Aid for Cancer

   The primary objective of this study is to establish the performance of two blood-based diagnostic aid test for cancer detection in individuals presenting with symptoms, signs, or findings suggestive of cancer.

   Stage

   Not phased

   Ages

   45 and older

   Site

   Southern California Research Center, Coronado, California

   Locations

   39 in total

   Run by

   Harbinger Health

   See if you can join NCT07046260 on ClinicalTrials.gov

4. A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)

   This study looks to advance a novel and potent strategy to eliminate minimal residual disease (MRD) in triple negative breast cancer (TNBC) present even after multimodal treatment, thereby improving survival and increasing cure rate in this aggressive cancer. Patients with locally advanced TNBC are…

   Stage

   Phase 1

   Ages

   18 to 99

   Site

   Los Angeles General Medical Center, Los Angeles, California

   Locations

   3 in total

   Run by

   University of Southern California

   See if you can join NCT04333706 on ClinicalTrials.gov

5. Supportive Care Intervention for Outpatient Stem Cell Transplant Patients

   The overall goal of this study is to assess the efficacy of the care.coach Avatar™ in improving anxiety and quality of life for patients undergoing outpatient transplant. After care.coach Avatar™ content and scheduling ("digital intervention" or "program") has been optimized for outpatient allogene…

   Stage

   Not phased

   Ages

   19 and older

   Site

   Dana-Farber Cancer Institute, Boston, Massachusetts

   Run by

   Victor Wang

   See if you can join NCT06564233 on ClinicalTrials.gov

6. Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions

   The purpose of this study is to determine whether a consultation with a Personalized Therapeutics Clinic, or PTC, will help participants lower the risk for side effects (drug-drug interactions and drug-gene interactions) when taking many medications and help providers improve prescribing decisions …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Chicago Medicine, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT05166694 on ClinicalTrials.gov

7. Ovarian Tissue Cryopreservation for Fertility Preservation

   The goal of this observational study is to learn about fertility preservation for pre-pubertal, peri-pubertal, and adult participants that are unable to pursue clinical standard of care fertility preservation such as egg (oocyte) and embryo cryopreservation. In addition, this study will provide res…

   Stage

   Not phased

   Ages

   Up to 39

   Site

   Magee-Womens Hospital, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT05875155 on ClinicalTrials.gov

8. Modernizing Instructions to Improve Treatment Participation of Subjects During Their First Radiotherapy

   Daily patient participation is critical to the successful, life-saving delivery of radiotherapy. There is very little in the literature describing the best way to prepare patients to give optimal participation. This study aims to look at an already-prepared conversion of patient instruction materia…

   Stage

   Not phased

   Ages

   18 to 99

   Site

   University of Florida, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT06246409 on ClinicalTrials.gov

9. Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

   This is a first-in-human (FIH), open label Phase 1/1b / Phase 2 study in patients with advanced metastatic solid tumors refractory to standard treatment. Phase 1 will identify potential optimal biologically relevant doses (OBRD) and the maximum tolerated dose (MTD) of MBRC-101 at one 1 or more dosi…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California

   Locations

   17 in total

   Run by

   MBrace Therapeutics

   See if you can join NCT06014658 on ClinicalTrials.gov

10. Positron Emission Tomography (PET) Imaging of Thrombosis

    The purpose of the study is to evaluate a new radiotracer called 64Cu-FBP8 for PET-MR imaging of thrombosis. The tracer has the potential of detecting thrombosis anywhere in the body, for instance in the left atrial appendage of patients with atrial fibrillation, and thereby may provide a non-invas…

    Stage

    Phase 1

    Ages

    18 to 85

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT03830320 on ClinicalTrials.gov

11. Cultural Tailoring and Pilot Testing of an Inpatient Yoga Therapy Program for Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation in India, Tanzania, and the United States

    To develop and measure the effects of a culturally sensitive yoga program for inpatients

    Stage

    Not phased

    Ages

    18 and older

    Site

    M D Anderson Cancer Center, Houston, Texas

    Locations

    3 in total

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT05681026 on ClinicalTrials.gov

12. Food and Microbiome Longitudinal Investigation (FAMiLI)

    The NYU Human Microbiome Study Cohort is designed to improve understanding of the role of human microbiome in health and disease. This study will serve as a critical NYU biorepository resource for research on human genetics and the microbiome in health and disease

    Stage

    Not phased

    Ages

    40 and older

    Site

    New York University School of Medicine, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT03293758 on ClinicalTrials.gov

13. Visual Communication: Digital Tool to Improve the Understanding of Treatment Options for Patients With Cancer and Increase Satisfaction of the Overall Experience for Patients, Caregivers, and Providers

    This is a study in patients with newly diagnosed cancer to prospectively evaluate the feasibility of integration of a visual communication tool for patients/caregivers/providers by determining whether such a tool can increase overall satisfaction with the patient experience.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT06927050 on ClinicalTrials.gov

14. Life at 100.4: An Immersive Social Virtual Reality (VR) Education Tool for Adolescent and Young Adult Cancer Patients and Caregivers

    The purpose of this study is to design and Beta test the Life at 100.4, an immersive social virtual reality education tool, with an anticipated 5 patient-caregiver-provider triads.Patients at Yale Pediatric Hematology and Oncology with a new oncologic diagnosis and their caregivers will be eligible…

    Stage

    Not phased

    Ages

    13 to 39

    Site

    Pediatric Hematology/Oncology Clinic in Smilow Cancer Hospital, New Haven, Connecticut

    Run by

    Yale University

    See if you can join NCT07224204 on ClinicalTrials.gov

15. TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

    This study is a non-interventional, multicenter, multicohort evaluation of participants with cancer who will undergo longitudinal plasma ctDNA biomarker profiling at specific time points in addition to standard of care therapy.

    Stage

    Not phased

    Ages

    18 to 99

    Site

    Alabama Oncology, Birmingham, Alabama

    Locations

    32 in total

    Run by

    Tempus AI

    See if you can join NCT06207032 on ClinicalTrials.gov

16. Re-Engaging AYA Survivors in Cancer-Related Healthcare

    The goal of this clinical trial is to test the efficacy (how well they work) of different digital interventions that deliver information to adolescent and young adult (AYA) survivors of childhood cancer to promote re-engagement in cancer-related long-term follow-up care (LTFU). The main aims are: *…

    Stage

    Not phased

    Ages

    15 to 29

    Site

    Nationwide Children's Hospital, Columbus, Ohio

    Locations

    3 in total

    Run by

    Children's Hospital of Philadelphia

    See if you can join NCT07138040 on ClinicalTrials.gov

17. Prevent Cancer- Greenville

    Prevent Cancer-Greenville was created to provide individuals with the opportunity to have their risk of developing cancer studied. Some individuals may be at a higher risk due to their personal lifestyle, family history and/or exposures. If subjects are found to be at high risk for developing a dis…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Prisma Health-Upstate, Greenville, South Carolina

    Run by

    Prisma Health-Upstate

    See if you can join NCT04947098 on ClinicalTrials.gov

18. Rehabilitation Outcomes Study

    This pilot health services interventional study aims to prospectively assess the effectiveness of a pre-treatment rehabilitation (prehabilitation) program across a diverse cohort of adult cancer patients via a randomized pilot trial. Upon screening and identification of high-risk features through a…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The N.C. Cancer Hospital, Chapel Hill, North Carolina

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT06674889 on ClinicalTrials.gov

19. From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care

    This observational study aims to identify the factors that influence whether cancer patients accept or decline supportive care services after screening positive for health-related social needs (HRSNs) at the Sidney Kimmel Comprehensive Cancer Center. The study focuses on adult oncology patients who…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania

    Run by

    Thomas Jefferson University

    See if you can join NCT07352579 on ClinicalTrials.gov

20. Cancer and Mild Cognitive Impairment Dyadic Intervention

    The purpose of this study is to see whether programs that include both a patient and their spouse or a patient and family caregiver (known as a dyad) are helpful for families in which one member of the dyad has cancer and mild memory difficulties and/or concerns. Participant and their spouse or par…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Duke University, Durham, North Carolina

    Run by

    Duke University

    See if you can join NCT05144516 on ClinicalTrials.gov

21. Legal Evaluation for Greater Access to Cancer Care (LEGAL-CARE)

    This study aims to help patients with cancer facing legal issues. The investigators noticed that many patients struggle with laws and regulations related to disability benefits, employment rules, health insurance denials, and financial assistance barriers among many others. To understand this bette…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Kirklin Clinic, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT07197515 on ClinicalTrials.gov

22. DOAC - Dosing Options in AntiCoagulation Prophylaxis

    Blood clots, also known as venous thromboembolism (VTE), are a common and serious complication for people with cancer. They can lead to pain, hospitalizations, delayed cancer treatment, and even death. Although national guidelines recommend using blood thinners (anticoagulants) to prevent clots in …

    Stage

    Phase 3

    Ages

    18 and older

    Site

    University of Vermont Medical Center, Burlington, Vermont

    Run by

    University of Vermont

    See if you can join NCT07005024 on ClinicalTrials.gov

23. Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions

    This is a randomized control trial of patients with suspected malignant pleural effusions to compare whether patients who have a thoracentesis or pleuroscopy (pleural biopsy) obtain an adequate biopsy, achieve a diagnosis, and begin cancer-directed therapy faster.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mount Sinai West, New York, New York

    Locations

    2 in total

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT06892691 on ClinicalTrials.gov

24. Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

    This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 …

    Stage

    Not phased

    Ages

    20 to 89

    Site

    Allegheny General Hospital, Pittsburgh, Pennsylvania

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT07023887 on ClinicalTrials.gov

25. Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer

    In this study, the investigators hypothesize that a high dose of post-workout protein nutrition regimen focused on food quality and an observed exercise regimen utilizing high-load resistance training initiated during or after cancer treatment will improve body composition and functional capacity.

    Stage

    Not phased

    Ages

    20 to 89

    Site

    Allegheny General Hospital, Pittsburgh, Pennsylvania

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT06858449 on ClinicalTrials.gov