Cancer Clinical Trials in Durham, North Carolina

10 studies are recruiting for cancer in Durham, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. FOG-001 in Locally Advanced or Metastatic Solid Tumors

   The goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in participants with familial adenomatous polyposis (FAP).

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Duke University, Durham, North Carolina

   Locations

   33 in total

   Run by

   Parabilis Medicines, Inc.

   See if you can join NCT05919264 on ClinicalTrials.gov

2. Pan Tumor Rollover Study

   Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Local Institution - 0016, Durham, North Carolina

   Locations

   399 in total

   Run by

   Bristol-Myers Squibb

   See if you can join NCT03899155 on ClinicalTrials.gov

3. A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

   The purpose of this study is to characterize the safety and tolerability of ALTA3263 in adults with advanced solid tumors with KRAS mutations.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Research Site, Durham, North Carolina

   Locations

   12 in total

   Run by

   Alterome Therapeutics, Inc.

   See if you can join NCT06835569 on ClinicalTrials.gov

4. Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

   This research study is investigating the safety and effectiveness of using combination of isatuximab, lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The study team will use lower doses than is currently standard for these drugs. Lower doses will be used t…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Duke Comprehensive Cancer Center, Durham, North Carolina

   Locations

   5 in total

   Run by

   UNC Lineberger Comprehensive Cancer Center

   See if you can join NCT05145400 on ClinicalTrials.gov

5. Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery

   In this pragmatic clinical trial, the investigators will study older Veterans approaching surgery for gastrointestinal or genitourinary cancer who are at high risk for a marked decline in their physical function. The investigators will test a multi-targeted nutrition regimen high in protein and oth…

   Stage

   Not phased

   Ages

   55 and older

   Site

   Durham VA Medical Center, Durham, NC, Durham, North Carolina

   Run by

   VA Office of Research and Development

   See if you can join NCT05912257 on ClinicalTrials.gov

6. Improving Outcomes in Early Menopause After Cancer

   The goal of this study is to create and test a new program led by nurse navigators to help women who experience early menopause after cancer. The program includes personalized menopause education, decision support, and skills to manage menopause symptoms. The main questions it aims to answer are: 1…

   Stage

   Not phased

   Ages

   18 to 44

   Site

   Duke Cancer Institute, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06982677 on ClinicalTrials.gov

7. Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors

   The purpose of this study is to evaluate the feasibility and acceptability of the Mindset Moments™ (MM™) program in managing psychological distress and resiliency in adolescent and young adult cancer survivors. Study participation will involve attending 8 weekly, one hour, live online group session…

   Stage

   Not phased

   Ages

   19 to 25

   Site

   Duke Cancer Institute, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06732375 on ClinicalTrials.gov

8. Cancer and Mild Cognitive Impairment Dyadic Intervention

   The purpose of this study is to see whether programs that include both a patient and their spouse or a patient and family caregiver (known as a dyad) are helpful for families in which one member of the dyad has cancer and mild memory difficulties and/or concerns. Participant and their spouse or par…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Duke University, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT05144516 on ClinicalTrials.gov

9. Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

   The purpose of this study is to determine the effectiveness of a digital health program called AYA STEPS, which is designed to help adolescent and young adult (AYA) cancer survivors manage symptoms and engage in recommended follow-up care.

   Stage

   Not phased

   Ages

   18 to 39

   Site

   Duke Cancer Institute, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06371768 on ClinicalTrials.gov

10. Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)

    While chronic cancer pain affecting as many as 75% of patients is typically addressed using pharmacologic interventions, experts and patients alike support maximizing any relevant non-pharmacologic interventions as well, such as cognitive behavioral therapy. Virtual reality, a novel technology that…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Duke University School of Medicine, Durham, North Carolina

    Locations

    2 in total

    Run by

    Medstar Health Research Institute

    See if you can join NCT07318519 on ClinicalTrials.gov