Cancer Clinical Trials in Pittsburgh, Pennsylvania

17 studies are recruiting for cancer in Pittsburgh, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Abatacept in Immune Checkpoint Inhibitor Myocarditis

    The primary aim is to test whether abatacept, as compared to placebo, is associated with a reduction in major adverse cardiac events (MACE) among participants hospitalized with myocarditis secondary to an immune checkpoint inhibitor (ICI). The primary outcome, MACE, is a composite of first occurren…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Allegheny-Singer Research Institution, Pittsburgh, Pennsylvania
    Locations
    31 in total
    Run by
    Massachusetts General Hospital
  2. FOG-001 in Locally Advanced or Metastatic Solid Tumors

    The goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in participants with familial adenomatous polyposis (FAP).

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh, Pennsylvania
    Locations
    33 in total
    Run by
    Parabilis Medicines, Inc.
  3. EXERT-BC Cardio: Cardio or Conditioning Training With Breast Cancer

    In this study, the investigators hypothesize that observed intense resistance training with conditioning elicits similar changes in body composition, muscle mass, and blood pressure as that with cardiovascular training (or cardio) for women treated with breast cancer.

    Stage
    Not phased
    Ages
    20 to 89
    Site
    AHN Allegheny General Hospital, Pittsburgh, Pennsylvania
    Run by
    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
  4. Investigating Real-Time Immunotherapy Symptoms Study

    The goal of this study is to evaluate the feasibility of using information from wearable devices and self-reported symptoms to remotely monitor patients during immunotherapy. The main questions it aims to answer are: * Is the digital remote patient monitoring tool feasible and acceptable to patient…

    Stage
    Not phased
    Ages
    18 and older
    Site
    UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
    Run by
    University of Pittsburgh
  5. Pan Tumor Rollover Study

    Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Local Institution - 0110, Pittsburgh, Pennsylvania
    Locations
    399 in total
    Run by
    Bristol-Myers Squibb
  6. EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

    This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.

    Stage
    Not phased
    Ages
    20 to 89
    Site
    AHN CI Exercise Oncology and Resiliency Center, Pittsburgh, Pennsylvania
    Run by
    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
  7. Childhood Cancer Survivor Study

    The Childhood Cancer Survivor Study (CCSS) will investigate the long-term effects of cancer and its associated therapies. A retrospective cohort study will be conducted through a multi-institutional collaboration, which will involve the identification and active follow-up of a cohort of approximate…

    Stage
    Not phased
    Ages
    Any age
    Site
    Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania
    Locations
    31 in total
    Run by
    St. Jude Children's Research Hospital
  8. Dietary Interventions in Cancer Patients Treated With Immune Checkpoint Inhibitors

    This pilot trial will study the potential impact of two distinct dietary interventions with sequential use of high-fermented foods and high-fiber supplements on the gut microbiome and antitumor immunity in patients with melanoma and non-small cell lung cancer (NSCLC) treated with immune checkpoint …

    Stage
    Not phased
    Ages
    18 and older
    Site
    UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
    Run by
    University of Pittsburgh
  9. ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

    The study's purpose is to establish the safety and tolerability of IMA203/IMA203CD8 products with or without combination with nivolumab in patients with solid tumors that express preferentially expressed antigen in melanoma (PRAME).

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    Locations
    21 in total
    Run by
    Immatics US, Inc.
  10. Testicular Tissue Cryopreservation for Fertility Preservation

    Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the ultimate goal that their tissue may be used in the future to restore fer…

    Stage
    Not phased
    Ages
    Any age
    Site
    Magee-Womens Hospital, Pittsburgh, Pennsylvania
    Run by
    University of Pittsburgh
  11. Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting

    Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transpl…

    Stage
    Not phased
    Ages
    Any age
    Site
    Magee-Womens Hospital, Pittsburgh, Pennsylvania
    Run by
    University of Pittsburgh
  12. Ovarian Tissue Cryopreservation for Fertility Preservation

    The goal of this observational study is to learn about fertility preservation for pre-pubertal, peri-pubertal, and adult participants that are unable to pursue clinical standard of care fertility preservation such as egg (oocyte) and embryo cryopreservation. In addition, this study will provide res…

    Stage
    Not phased
    Ages
    Up to 39
    Site
    Magee-Womens Hospital, Pittsburgh, Pennsylvania
    Run by
    University of Pittsburgh
  13. Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

    This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 …

    Stage
    Not phased
    Ages
    20 to 89
    Site
    Allegheny General Hospital, Pittsburgh, Pennsylvania
    Run by
    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
  14. Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer

    In this study, the investigators hypothesize that a high dose of post-workout protein nutrition regimen focused on food quality and an observed exercise regimen utilizing high-load resistance training initiated during or after cancer treatment will improve body composition and functional capacity.

    Stage
    Not phased
    Ages
    20 to 89
    Site
    Allegheny General Hospital, Pittsburgh, Pennsylvania
    Run by
    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
  15. Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

    This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery. This project is considered "Research" and participation is voluntary. Upon enrollment in this study, the r…

    Stage
    Not phased
    Ages
    18 to 89
    Site
    AHN West Penn Hospital, Pittsburgh, Pennsylvania
    Run by
    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
  16. Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

    The purpose of this prospective cohort study is to assess clinical and quality of life measures as well as to define the severity of adverse effects for the use of the RefleXion system to deliver intensity-modulated radiotherapy (IMRT), stereotactic body radiotherapy (SBRT), or SCINTIX Biology-guid…

    Stage
    Not phased
    Ages
    Any age
    Site
    University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    Locations
    5 in total
    Run by
    RefleXion Medical
  17. A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

    KB707-01 is a Phase 1/2, open-label, multicenter, dose escalation and expansion study. The study will evaluate the safety and tolerability of KB707 in adults with locally advanced or metastatic solid tumors who have progressed on standard of care therapy, cannot tolerate standard of care therapy, r…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
    Locations
    15 in total
    Run by
    Krystal Biotech, Inc.

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.