Cancer Clinical Trials in Philadelphia, Pennsylvania

23 studies are recruiting for cancer in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

  1. IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer

    The purpose of this research is to assess how patients with cancer being treated with Immune Checkpoint Inhibitors (ICI) manage symptoms related to cancer and/or its treatment. Patients use a variety of ways to manage symptoms including traditional and alternative treatments including cannabis, acu…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Thomas Jefferson University, Philadelphia, Pennsylvania
    Locations
    2 in total
    Run by
    State University of New York at Buffalo

    See if you can join NCT06206941 on ClinicalTrials.gov

  2. Abatacept in Immune Checkpoint Inhibitor Myocarditis

    The primary aim is to test whether abatacept, as compared to placebo, is associated with a reduction in major adverse cardiac events (MACE) among participants hospitalized with myocarditis secondary to an immune checkpoint inhibitor (ICI). The primary outcome, MACE, is a composite of first occurren…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    University of Pennsylvania, Philadelphia, Pennsylvania
    Locations
    31 in total
    Run by
    Massachusetts General Hospital

    See if you can join NCT05335928 on ClinicalTrials.gov

  3. Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients

    This study compares two methods of prescribing parenteral nutrition (PN) in adults with cancer who are unable to meet nutritional needs by oral or enteral intake.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Fox Chase Cancer Center, Philadelphia, Pennsylvania
    Run by
    Fox Chase Cancer Center

    See if you can join NCT07776704 on ClinicalTrials.gov

  4. FOG-001 in Locally Advanced or Metastatic Solid Tumors

    The goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in participants with familial adenomatous polyposis (FAP).

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania
    Locations
    33 in total
    Run by
    Parabilis Medicines, Inc.

    See if you can join NCT05919264 on ClinicalTrials.gov

  5. Pan Tumor Rollover Study

    Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Local Institution, Philadelphia, Pennsylvania
    Locations
    399 in total
    Run by
    Bristol-Myers Squibb

    See if you can join NCT03899155 on ClinicalTrials.gov

  6. Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

    Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve…

    Stage
    Phase 2
    Ages
    2 to 25
    Site
    Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    Locations
    5 in total
    Run by
    Children's Hospital of Philadelphia

    See if you can join NCT06458036 on ClinicalTrials.gov

  7. Evaluation of Grief Therapy Approaches for Bereaved Parents

    The purpose of this study is to compare three types of support programs for parents who have lost a child. The study will see how these support programs affect participants' grief and depression symptoms. The three support programs are called Meaning-Centered Grief Therapy, Supportive Counseling, a…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Children's Hospital of Philadelphia (Data Collection Only), Philadelphia, Pennsylvania
    Locations
    5 in total
    Run by
    University of Miami

    See if you can join NCT05142605 on ClinicalTrials.gov

  8. Childhood Cancer Survivor Study

    The Childhood Cancer Survivor Study (CCSS) will investigate the long-term effects of cancer and its associated therapies. A retrospective cohort study will be conducted through a multi-institutional collaboration, which will involve the identification and active follow-up of a cohort of approximate…

    Stage
    Not phased
    Ages
    Any age
    Site
    Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    Locations
    31 in total
    Run by
    St. Jude Children's Research Hospital

    See if you can join NCT01120353 on ClinicalTrials.gov

  9. Engaging M-health for Symptom Monitoring and Health Promotion for Women on Endocrine Therapy for Breast Cancer (EmSHAPE)

    The purpose of the study is to learn more about ways to help patients understand and manage side-effects from hormone therapy. The investigators will use the information from this study to design future studies to better understand how our well our tools work to help patients monitor and manage sym…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania
    Run by
    Abramson Cancer Center at Penn Medicine

    See if you can join NCT07454499 on ClinicalTrials.gov

  10. Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients

    Einstein Medical Center in Philadelphia serves a diverse group of the patient population. The majority of patients have a diverse cultural background, low literacy, and poor social-economic status. Medication adherence for chronic medical problems is in a range of 40-70%. Medication adherence among…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Albert Einstein Healthcare Network, Philadelphia, Pennsylvania
    Run by
    Thomas Jefferson University

    See if you can join NCT03245411 on ClinicalTrials.gov

  11. ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

    The study's purpose is to establish the safety and tolerability of IMA203/IMA203CD8 products with or without combination with nivolumab in patients with solid tumors that express preferentially expressed antigen in melanoma (PRAME).

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of Pennsylvania, Perelamn Center for Advanced Medicine, Philadelphia, Pennsylvania
    Locations
    21 in total
    Run by
    Immatics US, Inc.

    See if you can join NCT03686124 on ClinicalTrials.gov

  12. Massage Impact on Sleep in Pediatric Oncology

    This study aims to determine the impact of massage therapy for pediatric patients receiving intensive chemotherapy or stem cell transplant (SCT).

    Stage
    Not phased
    Ages
    12 to 21
    Site
    Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    Locations
    2 in total
    Run by
    Children's Hospital of Philadelphia

    See if you can join NCT06892158 on ClinicalTrials.gov

  13. A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

    The goal of this clinical trial is to test CPO301, a type of drug called an antibody drug conjugate in adult patients with advanced or metastatic solid tumors. The main questions it aims to answer are: * To assess the safety and tolerability of CPO301 at increasing doses and determine the dose to b…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Fox Chase Cancer Center, Philadelphia, Pennsylvania
    Locations
    14 in total
    Run by
    Conjupro Biotherapeutics, Inc.

    See if you can join NCT05948865 on ClinicalTrials.gov

  14. Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)

    The purpose of the study is to understand patient interest in telehealth and digital tools for pre-test genetic education and/or disclosure of genetic test results. Participants will receive telehealth genetic counseling in the home and may be offered various digital tools to help with the counseli…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania
    Run by
    Abramson Cancer Center at Penn Medicine

    See if you can join NCT07471958 on ClinicalTrials.gov

  15. Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

    This is a first-in-human (FIH), open label Phase 1/1b / Phase 2 study in patients with advanced metastatic solid tumors refractory to standard treatment. Phase 1 will identify potential optimal biologically relevant doses (OBRD) and the maximum tolerated dose (MTD) of MBRC-101 at one 1 or more dosi…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of Pennsylvania, Abramson Cancer Center, Philadelphia, Pennsylvania
    Locations
    17 in total
    Run by
    MBrace Therapeutics

    See if you can join NCT06014658 on ClinicalTrials.gov

  16. Re-Engaging AYA Survivors in Cancer-Related Healthcare

    The goal of this clinical trial is to test the efficacy (how well they work) of different digital interventions that deliver information to adolescent and young adult (AYA) survivors of childhood cancer to promote re-engagement in cancer-related long-term follow-up care (LTFU). The main aims are: *…

    Stage
    Not phased
    Ages
    15 to 29
    Site
    Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    Locations
    3 in total
    Run by
    Children's Hospital of Philadelphia

    See if you can join NCT07138040 on ClinicalTrials.gov

  17. From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care

    This observational study aims to identify the factors that influence whether cancer patients accept or decline supportive care services after screening positive for health-related social needs (HRSNs) at the Sidney Kimmel Comprehensive Cancer Center. The study focuses on adult oncology patients who…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania
    Run by
    Thomas Jefferson University

    See if you can join NCT07352579 on ClinicalTrials.gov

  18. eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

    This randomized non-inferiority study will use a 2x2 design where traditional standard-of-care pre-test (visit 1) and post-test (visit 2: disclosure) counseling delivered by a genetic counselor are replaced with a self-directed web-based eHealth intervention to provide critical data to inform optim…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania
    Run by
    Abramson Cancer Center at Penn Medicine

    See if you can join NCT05427240 on ClinicalTrials.gov

  19. Autoimmunity After Checkpoint Blockade

    The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity. Specifically, we wish to understand the genetics and immune system features that cause a subset of cancer patients treated with checkpoint …

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Pennsylvania - Abramson Cancer Center, Philadelphia, Pennsylvania
    Run by
    Abramson Cancer Center at Penn Medicine

    See if you can join NCT04119713 on ClinicalTrials.gov

  20. Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

    Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve…

    Stage
    Phase 2
    Ages
    2 to 99
    Site
    Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    Locations
    5 in total
    Run by
    Children's Hospital of Philadelphia

    See if you can join NCT05783323 on ClinicalTrials.gov

  21. Cannabis Use and Outcomes in Black and White Patients With Cancer

    The goal of the observational study is to learn how black and white patients with solid tumor cancer use cannabis, opioids and tobacco. The investigators are using momentary ecological assessment through a smart phone app and surveys to assess patient-reported pain and other symptoms as to inform c…

    Stage
    Not phased
    Ages
    21 to 99
    Site
    Thomas Jefferson University, Philadelphia, Pennsylvania
    Locations
    3 in total
    Run by
    State University of New York at Buffalo

    See if you can join NCT06037681 on ClinicalTrials.gov

  22. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical…

    Stage
    Not phased
    Ages
    Any age
    Site
    Massive Bio SYNERGY-AI site, Philadelphia, Pennsylvania
    Locations
    68 in total
    Run by
    Massive Bio, Inc.

    See if you can join NCT03452774 on ClinicalTrials.gov

  23. Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)

    This is a randomized trial of intensified post-discharge surveillance (Intervention Arm) versus standard post-discharge surveillance (Control Arm).

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Fox Chase Cancer Center - Philadelphia, Philadelphia, Pennsylvania
    Run by
    Fox Chase Cancer Center

    See if you can join NCT05454280 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.