Cancer Clinical Trials in Los Angeles, California

17 studies are recruiting for cancer in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

   AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 effects and safety at various dose levels in an all-comers advanced solid cancer patient population. AGX101will be administered intravenously. Dosing of AGX101 will be re…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   USC/Norris Comprehensive Cancer Center, Los Angeles, California

   Locations

   7 in total

   Run by

   Angiex, Inc.

   See if you can join NCT06440005 on ClinicalTrials.gov

2. Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

   This protocol is a retrospective study using observational data to conduct a target trial emulation to examine the association of exercise on cancer specific endpoints and other clinical outcomes in cancer survivors.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, Los Angeles (Data or Specimen Analysis Only), Los Angeles, California

   Locations

   3 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT07030686 on ClinicalTrials.gov

3. Effect of Meal Timing During Adjuvant Treatment for Cancer

   The goal of this clinical trial is to test meal-timing as a novel and sustainable interventional approach during cancer treatment to improve therapeutic response, patient well-being and long-term metabolic health. In alignment with these priorities, we propose to focus on patients with histological…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars Sinai Medical Center (CSMC), Los Angeles, California

   Run by

   Fred Hutchinson Cancer Center

   See if you can join NCT07524218 on ClinicalTrials.gov

4. Abatacept in Immune Checkpoint Inhibitor Myocarditis

   The primary aim is to test whether abatacept, as compared to placebo, is associated with a reduction in major adverse cardiac events (MACE) among participants hospitalized with myocarditis secondary to an immune checkpoint inhibitor (ICI). The primary outcome, MACE, is a composite of first occurren…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   31 in total

   Run by

   Massachusetts General Hospital

   See if you can join NCT05335928 on ClinicalTrials.gov

5. FOG-001 in Locally Advanced or Metastatic Solid Tumors

   The goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in participants with familial adenomatous polyposis (FAP).

   Stage

   Phase 1

   Ages

   18 and older

   Site

   University of California, Los Angeles (UCLA), Los Angeles, California

   Locations

   33 in total

   Run by

   Parabilis Medicines, Inc.

   See if you can join NCT05919264 on ClinicalTrials.gov

6. The STOP-MED CTRCD Trial

   Cancer therapy-related cardiac dysfunction (CTRCD) is when the heart's ability to pump oxygenated blood to the body is compromised. It is a side effect of cancer therapy which can occur as commonly as in 1 in 5 patients. When this occurs, heart failure medications are started to protect the heart f…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   University of California, Los Angeles, Los Angeles, California

   Locations

   14 in total

   Run by

   Dinesh Thavendiranathan

   See if you can join NCT06183437 on ClinicalTrials.gov

7. Childhood Cancer Survivor Study

   The Childhood Cancer Survivor Study (CCSS) will investigate the long-term effects of cancer and its associated therapies. A retrospective cohort study will be conducted through a multi-institutional collaboration, which will involve the identification and active follow-up of a cohort of approximate…

   Stage

   Not phased

   Ages

   Any age

   Site

   Children's Hospital Los Angeles, Los Angeles, California

   Locations

   31 in total

   Run by

   St. Jude Children's Research Hospital

   See if you can join NCT01120353 on ClinicalTrials.gov

8. A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

   The goal of this study is to test autologous logic-gated Tmod™ CAR T-cell products in subjects with solid tumors including colorectal cancer (CRC), pancreatic cancer (PANC), non-small cell lung cancer (NSCLC), ovarian cancer (OVCA), mesothelioma (MESO), and other solid tumors that express mesotheli…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   UCLA Medical Center, Los Angeles, California

   Locations

   12 in total

   Run by

   A2 Biotherapeutics Inc.

   See if you can join NCT06051695 on ClinicalTrials.gov

9. Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

   This cluster-randomized comparative effectiveness trial compares a technology-based supportive cancer care (SCC) approach with a redesigned team-based supportive cancer care (SCC) approach.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Oncology Institute for Hope and Innovation, Los Angeles, California

   Locations

   17 in total

   Run by

   Stanford University

   See if you can join NCT05297734 on ClinicalTrials.gov

10. A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

    The goal of this clinical trial is to test CPO301, a type of drug called an antibody drug conjugate in adult patients with advanced or metastatic solid tumors. The main questions it aims to answer are: * To assess the safety and tolerability of CPO301 at increasing doses and determine the dose to b…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    USC Norris Comprehensive Cancer Center, Los Angeles, California

    Locations

    14 in total

    Run by

    Conjupro Biotherapeutics, Inc.

    See if you can join NCT05948865 on ClinicalTrials.gov

11. A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)

    This study looks to advance a novel and potent strategy to eliminate minimal residual disease (MRD) in triple negative breast cancer (TNBC) present even after multimodal treatment, thereby improving survival and increasing cure rate in this aggressive cancer. Patients with locally advanced TNBC are…

    Stage

    Phase 1

    Ages

    18 to 99

    Site

    Los Angeles General Medical Center, Los Angeles, California

    Locations

    3 in total

    Run by

    University of Southern California

    See if you can join NCT04333706 on ClinicalTrials.gov

12. eMOTION: Examining Implicit Attitudes in Physical Activity Engagement

    This early-phase trial will test intervention strategies to influence implicit attitudes towards physical activity and determine whether changes in those mechanisms result in change in physical activity behavior among inactive adults who are overweight or obese.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Univeristy of Southern California, Los Angeles, California

    Run by

    University of Southern California

    See if you can join NCT07044570 on ClinicalTrials.gov

13. A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

    The goal of this study is to test A2B395, an allogeneic logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorectal cancer (CRC), non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), triple-negative breast cancer (TNBC), renal cell carcinoma…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    UCLA Medical Center, Los Angeles, California

    Locations

    10 in total

    Run by

    A2 Biotherapeutics Inc.

    See if you can join NCT06682793 on ClinicalTrials.gov

14. eMOTION: Examining Affective Mechanisms in Physical Activity Engagement

    This early-phase trial will test intervention strategies to influence affective mechanisms underlying physical activity and determine whether changes in those mechanisms result in change in physical activity behavior among inactive adults who are overweight or obese.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Southern California, Los Angeles, California

    Run by

    University of Southern California

    See if you can join NCT06570642 on ClinicalTrials.gov

15. A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

    KB707-01 is a Phase 1/2, open-label, multicenter, dose escalation and expansion study. The study will evaluate the safety and tolerability of KB707 in adults with locally advanced or metastatic solid tumors who have progressed on standard of care therapy, cannot tolerate standard of care therapy, r…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    UCLA Health, Los Angeles, California

    Locations

    15 in total

    Run by

    Krystal Biotech, Inc.

    See if you can join NCT05970497 on ClinicalTrials.gov

16. Trial of DFP-14927 in Advanced Solid Tumors

    This is a Phase I, open-label, single-arm, dose escalation study of DFP-14927 intravenous infusion administered to patients with refractory or relapsed solid tumors.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    UCLA Department of Medicine- Hematology/Oncology, Los Angeles, California

    Locations

    2 in total

    Run by

    Delta-Fly Pharma, Inc.

    See if you can join NCT03943004 on ClinicalTrials.gov

17. Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment

    The investigators will recruit and enroll individuals that may have the KRAS-variant or other microRNA binding site mutations to join registry studies. The investigators will allow individuals to obtain their results through a physician at the completion of the studies. The investigators current fo…

    Stage

    Not phased

    Ages

    18 and older

    Site

    MiraKind, Los Angeles, California

    Run by

    MiraKind

    See if you can join NCT02253251 on ClinicalTrials.gov