Cancer Clinical Trials

252 studies are recruiting for cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 5

1. Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses

   This is a prospective, open-label navigational investigation designed to evaluate the feasibility of using molecular profile-based evidence to determine individualized cancer therapy for patients with aggressive malignancies. This is a non-randomized, histology-agnostic trial. Although there will b…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Froedtert Hospital & the Medical College of Wisconsin, Milwaukee, Wisconsin

   Run by

   Medical College of Wisconsin

   See if you can join NCT05674825 on ClinicalTrials.gov

2. Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer

   Determine the effects of the Computerized Symptom Assessment Tool (C-SCAT) versus usual care on the primary outcomes of self-efficacy for symptom management and symptom self-management behaviors

   Stage

   Not phased

   Ages

   15 to 29

   Site

   Children's Mercy Hospital, Kansas City, Missouri

   Locations

   5 in total

   Run by

   Virginia Commonwealth University

   See if you can join NCT05958316 on ClinicalTrials.gov

3. IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)

   The purpose of this research study is to evaluate a mobile application (app) for depression treatment called "Moodivate" among cancer survivors. Moodivate was developed by our research team to assist with the treatment of depressed mood. Participants will be randomly assigned to either download the…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Medical University of South Carolina, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT06582784 on ClinicalTrials.gov

4. A Study of Live Tumor Fragments of Surgical Resections

   The purpose of this study is to obtain unused resected tumor tissue sample and associated clinical data from patients enrolled in this study to research ex vivo treatment response and integrity of tumor microenvironment using omics analysis and imaging while maintaining cell stability in a live env…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Florida, Jacksonville, Florida

   Run by

   Mayo Clinic

   See if you can join NCT07000864 on ClinicalTrials.gov

5. A Study of Herbal Supplements in Cancer Survivors With Constipation

   The purpose of this study is to find out whether MZRW is an effective treatment for constipation in cancer survivors. The researchers will compare MZRW with placebo, a pill that looks like MZRW and is given in the same way, but contains no medication. The researchers will also study the effect MZRW…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Memorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge, New Jersey

   Locations

   7 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT07091084 on ClinicalTrials.gov

6. Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery

   In this pragmatic clinical trial, the investigators will study older Veterans approaching surgery for gastrointestinal or genitourinary cancer who are at high risk for a marked decline in their physical function. The investigators will test a multi-targeted nutrition regimen high in protein and oth…

   Stage

   Not phased

   Ages

   55 and older

   Site

   Durham VA Medical Center, Durham, NC, Durham, North Carolina

   Run by

   VA Office of Research and Development

   See if you can join NCT05912257 on ClinicalTrials.gov

7. Leading Healthy Eating and Activity Promotion Program

   The goal of the LEAP project is to improve the health and well-being of cancer survivors and their co-survivors living in persistent poverty areas by providing healthy behavior change support. This will be done by engaging the community in adapting beneficial approaches for promoting healthy diet a…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06868524 on ClinicalTrials.gov

8. xDRIVE for Florida-based Cancer Patients

   Through this study funded by the Florida Cancer Innovation Fund, First Ascent will demonstrate state-wide feasibility of providing xDRIVE Functional Precision Medicine + Artificial Intelligence platform by assessing patient clinical benefit and health economics impacts. As this is a feasibility stu…

   Stage

   Not phased

   Ages

   Any age

   Site

   First Ascent Biomedical, Miami, Florida

   Locations

   2 in total

   Run by

   First Ascent Biomedical Inc.

   See if you can join NCT07167381 on ClinicalTrials.gov

9. Improving Outcomes in Early Menopause After Cancer

   The goal of this study is to create and test a new program led by nurse navigators to help women who experience early menopause after cancer. The program includes personalized menopause education, decision support, and skills to manage menopause symptoms. The main questions it aims to answer are: 1…

   Stage

   Not phased

   Ages

   18 to 44

   Site

   Duke Cancer Institute, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06982677 on ClinicalTrials.gov

10. ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

    The study's purpose is to establish the safety and tolerability of IMA203/IMA203CD8 products with or without combination with nivolumab in patients with solid tumors that express preferentially expressed antigen in melanoma (PRAME).

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Stanford Cancer Institute, Stanford, California

    Locations

    21 in total

    Run by

    Immatics US, Inc.

    See if you can join NCT03686124 on ClinicalTrials.gov

11. On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety

    This study is evaluating On-Trac (Online Training After Cancer), an online educational intervention to teach adult cancer survivors strategies to address anxiety based on Cognitive-Behavioral Therapy (CBT) and Acceptance Commitment Therapy (ACT) The name of the study intervention is Online Training…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dana Farber Cancer Institute, Boston, Massachusetts

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT07305740 on ClinicalTrials.gov

12. UNC Childhood, Adolescent, and Young Adult Cancer Cohort

    Purpose: This study aims to create a registry of childhood, adolescent, and young adult patients with cancer (<40 years-old at cancer diagnosis), entitled the 'UNC Childhood, Adolescent, and Young Adult Cancer Cohort' (UNC-CAYACC). This resource will serve to support cancer outcomes research among …

    Stage

    Not phased

    Ages

    1 to 39

    Site

    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT05096923 on ClinicalTrials.gov

13. A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials

    The purpose of this study is to pilot test and evaluate an existing tailored ALEX (Agent Leveraging Empathy for eXams) Research Portal to navigate Black and Hispanic adult cancer patients and their family members through referral to cancer clinical trials.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Mayo Clinic in Florida, Jacksonville, Florida

    Locations

    3 in total

    Run by

    University of Florida

    See if you can join NCT05655494 on ClinicalTrials.gov

14. High-Resolution PET-CT Imaging for Surgical Margin Visualization

    Imaging will be exploratory and be used intraoperatively. There have been no discovered risks associated with the device to be used in this study, and none are anticipated given the diagnostic and non-invasive, 'ex vivo' nature of device use. Of note, the surgical resection will proceed as per stan…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt-Ingram Cancer Center

    See if you can join NCT06915454 on ClinicalTrials.gov

15. Intra- and Inter-fraction Changes in Radiation Therapy

    Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.

    Stage

    Not phased

    Ages

    Any age

    Site

    Froedtert Hospital, Milwaukee, Wisconsin

    Run by

    Medical College of Wisconsin

    See if you can join NCT02344121 on ClinicalTrials.gov

16. UNC Metastatic Cancer Radiation Therapy Registry

    The purpose of this registry is to collect clinical data from participants attending UNC Hospitals who present with metastatic cancer and are evaluated to receive radiation therapy as part of their standard of care treatment. The goal of this study is to provide a foundation for studies designed to…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill, North Carolina

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT06306924 on ClinicalTrials.gov

17. Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors

    The purpose of this study is to evaluate the feasibility and acceptability of the Mindset Moments™ (MM™) program in managing psychological distress and resiliency in adolescent and young adult cancer survivors. Study participation will involve attending 8 weekly, one hour, live online group session…

    Stage

    Not phased

    Ages

    19 to 25

    Site

    Duke Cancer Institute, Durham, North Carolina

    Run by

    Duke University

    See if you can join NCT06732375 on ClinicalTrials.gov

18. MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant Other

    The goal of this clinical trial is to assess feasibility, tolerability and preliminary effectiveness of MDMA-assisted therapy for adjustment disorder (AD) in 10 dyads of patients with cancer and a concerned significant other (CSO) (20 participants total). Participants will undergo an 8-week treatme…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Sunstone Medical, PC, Rockville, Maryland

    Run by

    Sunstone Medical

    See if you can join NCT05584826 on ClinicalTrials.gov

19. Care Coordination Educational Intervention Study for Patients From Rural Areas With Early Stage Cancer

    Care Coordination is an essential component of cancer care delivery. Many patients experience poor care coordination. In this study, we hypothesize that provision of a video educational intervention to teach patients about cancer, care coordination and self-advocacy will improve patients' perceptio…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Vermont Cancer Center, Burlington, Vermont

    Run by

    University of Vermont Medical Center

    See if you can join NCT05723250 on ClinicalTrials.gov

20. Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

    The purpose of this research study is to determine if lattice radiation therapy (LRT) will provide better treatment for bulky (large) tumors than current standard of care radiotherapy.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Cincinnati Medical Center, Cincinnati, Ohio

    Run by

    University of Cincinnati

    See if you can join NCT06416007 on ClinicalTrials.gov

21. Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

    This cluster-randomized comparative effectiveness trial compares a technology-based supportive cancer care (SCC) approach with a redesigned team-based supportive cancer care (SCC) approach.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Locations

    17 in total

    Run by

    Stanford University

    See if you can join NCT05297734 on ClinicalTrials.gov

22. A Nutrition & Exercise Prehabilitation Intervention on Inflammatory Biomarkers in AI Cancer Patients

    The purpose of this study is to assess the feasibility of a prehab intervention among American Indian (AI) patients diagnosed with cancer and measure inflammatory biomarkers to evaluate the preliminary impact of the trial intervention. The central hypothesis is that this community-informed prehab i…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    University of Arizona Cancer Center, Tucson, Arizona

    Run by

    University of Arizona

    See if you can join NCT06644560 on ClinicalTrials.gov

23. Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6

    This research study is studying a targeted therapy as a possible treatment for cancer abnormality in one of the following genes: CCND1, CCND2, CCND3, CDK4, or CDK6. The drug involved in this study is: -Abemaciclib

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Dana Farber Cancer Institute, Boston, Massachusetts

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT03310879 on ClinicalTrials.gov

24. Virtual Reality Therapy for Cancer-Treatment Associated Symptoms

    We propose an innovative approach to symptom management in cancer patients following cancer treatments, utilizing a Multimodal Integrative Therapy (MIT) delivered via Virtual Reality (VR) program, authorized by the US Food and Drug Administration for in-home use. Our primary goal is to generate pil…

    Stage

    Not phased

    Ages

    18 to 88

    Site

    Luana Colloca, Baltimore, Maryland

    Locations

    2 in total

    Run by

    University of Maryland, Baltimore

    See if you can join NCT06248216 on ClinicalTrials.gov

25. Improving Health Insurance Literacy Among Young Adult Cancer Survivors

    We will conduct a randomized controlled trial to test a 4-session virtual health insurance navigation intervention that will increase knowledge about health insurance, reduce financial burden, and improve surveillance for recurrence among 300 young adult cancer survivors ages 26 to 39. We will comb…

    Stage

    Not phased

    Ages

    26 to 45

    Site

    Intermountain Health, Murray, Utah

    Locations

    2 in total

    Run by

    University of Utah

    See if you can join NCT05829070 on ClinicalTrials.gov