Cancer Clinical Trials

252 studies are recruiting for cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 4

1. Comprehensive Tobacco Cessation for Cancer Patients and Survivors

   The purpose of this research study is to learn how best to incorporate tobacco cessation treatment into clinical care for cancer patients, survivors, and caregivers.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Virginia Commonwealth University, Richmond, Virginia

   Run by

   Virginia Commonwealth University

   See if you can join NCT05805722 on ClinicalTrials.gov

2. Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

   This study will collect tumor specimens with correlated clinical and demographic data from patients who are undergoing a biopsy or similar procedure to obtain tumor tissue as a normal course of their medical management or diagnostic work-up for suspected or confirmed cancer.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mercy Hospital - FTS, Fort Smith, Arkansas

   Locations

   8 in total

   Run by

   Elephas

   See if you can join NCT07327489 on ClinicalTrials.gov

3. Advancing Cancer Control Engaged Research Through Transformative Solutions (ACCERT) Social Determinants of Health (SDoH) Navigation Program

   The purpose of this study is to evaluate patient navigation programs designed to reduce barriers to cancer screening and improve healthcare experiences for adults living in Chicago. Participants will be asked to complete two surveys: the first survey shortly after the participants join the study an…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Northwestern University, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT07669753 on ClinicalTrials.gov

4. Survivorship Plan HEalth REcord (SPHERE) Implementation Trial

   To understand the effectiveness and implementation of the SCP-PHR, we will conduct a hybrid type 1 effectiveness-implementation trial consisting of the following components: (A) a randomized clinical effectiveness trial, and (B) a mixed methods implementation study.

   Stage

   Not phased

   Ages

   18 to 99

   Site

   Indiana University School of Medicine, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT05346796 on ClinicalTrials.gov

5. Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology

   This prospective study will test artificial intelligence (AI) and machine learning (ML) decision support tools. This tool is designed to help doctors, physicists and other staff during pre-treatment peer review, a step where treatment plans are checked before a patient begins care. The system highl…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill, North Carolina

   Run by

   UNC Lineberger Comprehensive Cancer Center

   See if you can join NCT07463833 on ClinicalTrials.gov

6. Comprehensive Connected Cancer Care (C4): Intervention Evaluation

   The C4 program aims to provide a multi-level intervention program (Patient Level, Healthcare Team and Healthcare System Level) that improves the coordination of care with supportive/ancillary care providers and community services through the use of patient navigation and a digital needs assessment …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Kentucky, Lexington, Kentucky

   Run by

   Timothy Mullett

   See if you can join NCT06326567 on ClinicalTrials.gov

7. Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer

   Childhood cancer predisposes to health risks that may not become apparent until many years after completion of therapy. The SJLIFE protocol is designed to establish a lifetime cohort of childhood cancer survivors treated at St. Jude Children's Research Hospital to facilitate evaluation of health ou…

   Stage

   Not phased

   Ages

   5 and older

   Site

   St. Jude Children's Research Hospital, Memphis, Tennessee

   Run by

   St. Jude Children's Research Hospital

   See if you can join NCT00760656 on ClinicalTrials.gov

8. Childhood Cancer Survivor Study

   The Childhood Cancer Survivor Study (CCSS) will investigate the long-term effects of cancer and its associated therapies. A retrospective cohort study will be conducted through a multi-institutional collaboration, which will involve the identification and active follow-up of a cohort of approximate…

   Stage

   Not phased

   Ages

   Any age

   Site

   University of Alabama at Birmingham/Children's of Alabama, Birmingham, Alabama

   Locations

   31 in total

   Run by

   St. Jude Children's Research Hospital

   See if you can join NCT01120353 on ClinicalTrials.gov

9. Lactulose to Improve Gut Health in Cancer Patients Receiving Immunotherapy

   The purpose of this study is to see if lactulose can improve the effectiveness of immunotherapy in patients with advanced cancer.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   University of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT07354100 on ClinicalTrials.gov

10. Evaluation of a Mobile App Program for Coping With Cancer

    The goal of this clinical trial is to learn if a mobile app program for people with a history of cancer can help treat distress. The main questions it aims to answer is: Do participants use the Tools for Coping with Cancer Calm Health mobile app and do they find it helpful? Does the Tools for Copin…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Smilow Cancer Hospital, New Haven, Connecticut

    Run by

    Yale University

    See if you can join NCT06923501 on ClinicalTrials.gov

11. A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

    The goal of this study is to test autologous logic-gated Tmod™ CAR T-cell products in subjects with solid tumors including colorectal cancer (CRC), pancreatic cancer (PANC), non-small cell lung cancer (NSCLC), ovarian cancer (OVCA), mesothelioma (MESO), and other solid tumors that express mesotheli…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Banner Health, Gilbert, Arizona

    Locations

    12 in total

    Run by

    A2 Biotherapeutics Inc.

    See if you can join NCT06051695 on ClinicalTrials.gov

12. Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

    The purpose of this study is to further understand the clinical impact and follow-up steps that may be required based on using whole-body Magnetic Resonance Imaging (MRI) or whole-body ultrasound and blood tests to detect multiple cancers in firefighters. This study involves an investigational test…

    Stage

    Not phased

    Ages

    35 to 85

    Site

    Inova Schar Cancer - Saville Cancer Screening and Prevention Center, Fairfax, Virginia

    Run by

    Inova Health Care Services

    See if you can join NCT06931561 on ClinicalTrials.gov

13. Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors

    The purpose of this study is to determine feasibility and acceptability of a six-week at-home light therapy protocol in childhood cancer survivors, to identify facilitators and barriers to implementing this intervention, and to measure signs and symptoms of Chemotherapy Induced Peripheral Neuropath…

    Stage

    Not phased

    Ages

    5 and older

    Site

    Yale New Haven Health Smilow York Street Hospital, New Haven, Connecticut

    Locations

    2 in total

    Run by

    Yale University

    See if you can join NCT07019259 on ClinicalTrials.gov

14. Engaging M-health for Symptom Monitoring and Health Promotion for Women on Endocrine Therapy for Breast Cancer (EmSHAPE)

    The purpose of the study is to learn more about ways to help patients understand and manage side-effects from hormone therapy. The investigators will use the information from this study to design future studies to better understand how our well our tools work to help patients monitor and manage sym…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    Abramson Cancer Center at Penn Medicine

    See if you can join NCT07454499 on ClinicalTrials.gov

15. Dietary Interventions in Cancer Patients Treated With Immune Checkpoint Inhibitors

    This pilot trial will study the potential impact of two distinct dietary interventions with sequential use of high-fermented foods and high-fiber supplements on the gut microbiome and antitumor immunity in patients with melanoma and non-small cell lung cancer (NSCLC) treated with immune checkpoint …

    Stage

    Not phased

    Ages

    18 and older

    Site

    UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania

    Run by

    University of Pittsburgh

    See if you can join NCT06475807 on ClinicalTrials.gov

16. A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

    The purpose of this study is to characterize the safety and tolerability of ALTA3263 in adults with advanced solid tumors with KRAS mutations.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Research Site, Orlando, Florida

    Locations

    12 in total

    Run by

    Alterome Therapeutics, Inc.

    See if you can join NCT06835569 on ClinicalTrials.gov

17. Patient Derived Preclinical Models

    Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinic…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT05324553 on ClinicalTrials.gov

18. Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

    This research study is investigating the safety and effectiveness of using combination of isatuximab, lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The study team will use lower doses than is currently standard for these drugs. Lower doses will be used t…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

    Locations

    5 in total

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT05145400 on ClinicalTrials.gov

19. Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

    The purpose of this study is to evaluate the safety and efficacy of administering the medication capecitabine along with temozolomide when you start your monthly regimen of oral temozolomide for the treatment of your newly diagnosed glioblastoma multiforme (GBM). Capecitabine is an oral chemotherap…

    Stage

    Phase 1

    Ages

    18 to 74

    Site

    Lenox Hill Brain Tumor Center, New York, New York

    Run by

    Northwell Health

    See if you can join NCT03213002 on ClinicalTrials.gov

20. My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life

    The purpose of this study is to examine the implementation and effectiveness of the psychosocial eHealth intervention, My Wellbeing Guide, on the proposed primary outcome, depressive symptoms, in patients diagnosed with cancer who receive care at Northwestern Medicine and the University of Miami He…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT05369429 on ClinicalTrials.gov

21. Active Living After Cancer: Implementation Within Be Well Acres Homes

    The goal of this research study is to learn more about a physical activity program adapted for cancer survivors.

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Texas M. D. Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT06907706 on ClinicalTrials.gov

22. Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients

    Einstein Medical Center in Philadelphia serves a diverse group of the patient population. The majority of patients have a diverse cultural background, low literacy, and poor social-economic status. Medication adherence for chronic medical problems is in a range of 40-70%. Medication adherence among…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Albert Einstein Healthcare Network, Philadelphia, Pennsylvania

    Run by

    Thomas Jefferson University

    See if you can join NCT03245411 on ClinicalTrials.gov

23. Daily Hand-Held Vibration Therapy

    The purpose of this pilot study is to determine the safety and feasibility of a daily 3-minute hand-held vibration therapy intervention to reduce the severity of CIPN in the hands. The investigators hypothesize that daily vibration therapy can reduce the severity of patient's CIPN in their hands an…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Indiana University Health West, Avon, Indiana

    Locations

    3 in total

    Run by

    Indiana University

    See if you can join NCT04207437 on ClinicalTrials.gov

24. Evaluating Genomic Testing in Human Cancer & Outcomes of Targeted Therapies

    This is a substudy (Part 2) of a larger two-part clinical trial including both observational and therapeutic (interventional) cohorts to assess the progression free survival ratio of patients treated with a targeted therapy based on genomic analysis results and recommendation by the Markey Cancer C…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Markey Cancer Center, University of Kentucky, Lexington, Kentucky

    Run by

    Rachel Miller

    See if you can join NCT03089554 on ClinicalTrials.gov

25. Galleri® in the Medicare Population.

    This multi-center comparative prospective cohort study is designed to assess the real world clinical impact, including safety and test performance, of Galleri®, a blood-based multi-cancer early detection (MCED) test. The study will seek enrollment that is representative of the Medicare population.

    Stage

    Not phased

    Ages

    50 and older

    Site

    Mercy Health - Fort Smith, Fort Smith, Arkansas

    Locations

    61 in total

    Run by

    GRAIL, Inc.

    See if you can join NCT05673018 on ClinicalTrials.gov