Stroke Clinical Trials

216 studies are recruiting for stroke in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 8

1. Cognition and Motor Learning Post-stroke

   This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship. The chosen experimental design integrates biomechanical analyses, neuropsychological…

   Stage

   EARLY_Phase 1

   Ages

   45 to 85

   Site

   Center for Health Professions, Los Angeles, California

   Run by

   University of Southern California

   See if you can join NCT04829071 on ClinicalTrials.gov

2. VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration

   The VOICE Study is an early feasibility study to evaluate the initial clinical safety and efficacy of the N1 and R1 Systems device design concept in providing an ability to communicate. The Neuralink N1 Implant is intended to provide the ability to communicate to individuals with severe and irrever…

   Stage

   Not phased

   Ages

   22 to 75

   Site

   The University of Texas Southwestern Medical Center, Dallas, Texas

   Run by

   Neuralink Corp

   See if you can join NCT07224256 on ClinicalTrials.gov

3. Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait

   This research aims to understand the effect of the Neuro20 Functional Electrical Stimulation Suit on autonomic nervous system function, muscle performance, and gait after amputation or neurologic injury.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brooks Rehabilitation, Jacksonville, Florida

   Locations

   2 in total

   Run by

   Brooks Rehabilitation

   See if you can join NCT07164846 on ClinicalTrials.gov

4. Cultural Modification of an Evidence Based Healthy Lifestyle Intervention for People Post Stroke Who Identify as Hispanic/Latino

   The purpose of this trial is to examine weight loss for Hispanic/Latino people with stroke (CVA) who take part in a healthy lifestyle program that has been culturally modified for Hispanic/Latino people

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Baylor Institute for Rehabilitation, Dallas, Texas

   Run by

   Baylor Research Institute

   See if you can join NCT06517459 on ClinicalTrials.gov

5. Stroke Recovery Initiative - Registry for Stroke Research Studies

   The Stroke Recovery Initiative is a nation-wide participant recruitment registry that connects people who have had a stroke with researchers who are working to develop new approaches to improve recovery after stroke.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT03318432 on ClinicalTrials.gov

6. Rehabilitation Strategies for Social Participation in Chronic Stroke Survivors

   The goal of this clinical trial is to test a new rehabilitation program, combining acceptance and commitment therapy with strategy training (ACES), to help people resume social participation after stroke and live in the community. Investigators will also compare the changes in social participation …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06758505 on ClinicalTrials.gov

7. Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke

   This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Northwestern University, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT06598150 on ClinicalTrials.gov

8. Use of Sensory Substitution to Improve Arm Control After Stroke

   Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) t…

   Stage

   Not phased

   Ages

   21 and older

   Site

   Marquette University, Milwaukee, Wisconsin

   Run by

   Marquette University

   See if you can join NCT03298243 on ClinicalTrials.gov

9. Improving Stroke Motor Control With Non-invasive Brain Stimulation and Functional Electrical Stimulation

   This pilot study for stroke patients with chronic upper limb hemiplegia will examine the effects of non-invasive brain stimulation and neuromuscular electrical stimulation on hand motor control and corticospinal excitability. Specifically, this study will investigate the effects of timing and deliv…

   Stage

   Not phased

   Ages

   21 and older

   Site

   MetroHealth Medical Center, Cleveland, Ohio

   Run by

   MetroHealth Medical Center

   See if you can join NCT03857529 on ClinicalTrials.gov

10. tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia

    After a stroke, it is very common to lose the ability to open the affected hand. Occupational and physical rehabilitation therapy (OT and PT) combined with non-invasive brain stimulation may help a person recover hand movement. The purpose of this study is to compare 3 non-invasive brain stimulatio…

    Stage

    Not phased

    Ages

    21 to 90

    Site

    MetroHealth Medical Center, Cleveland, Ohio

    Run by

    MetroHealth Medical Center

    See if you can join NCT05866003 on ClinicalTrials.gov

11. Blood Flow Regulation and Neuromuscular Function Post-Stroke

    The muscles of stroke survivors can fatigue faster compared to muscles in people who have not had a stroke, which can limit how long a person with stroke can perform tasks such as walking. This study will examine how blood flow is regulated to the exercising leg muscle post-stroke, because if the m…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    Medical College of Wisconsin, Milwaukee, Wisconsin

    Locations

    2 in total

    Run by

    Medical College of Wisconsin

    See if you can join NCT06027294 on ClinicalTrials.gov

12. MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes

    Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance. Preliminary data shows a single bout of ischemic conditioning or oral ingestion of an over-the-counter antioxidant supplement called Mit…

    Stage

    Phase 2

    Ages

    18 to 85

    Site

    Medical College of Wisconsin, Milwaukee, Wisconsin

    Run by

    Medical College of Wisconsin

    See if you can join NCT06930638 on ClinicalTrials.gov

13. BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement

    The investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health. The goal of this study is to compare two new ways of lowering blood pressure. The first way is to help people check their b…

    Stage

    Not phased

    Ages

    35 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT07091851 on ClinicalTrials.gov

14. Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic Stroke

    This research study aims to understand the relationship between brain stimulation and leg skill learning in both healthy adults and persons with chronic stroke.

    Stage

    Not phased

    Ages

    21 to 90

    Site

    Physical Therapy, University of Texas Medical Branch, Galveston, Texas

    Run by

    The University of Texas Medical Branch, Galveston

    See if you can join NCT06681207 on ClinicalTrials.gov

15. WIM Exosuit Wearable Soft Robot for Enhancing Walking Activity

    This study is to develop, test, and optimize a soft hip wearable robot for individuals who have experience a stroke.

    Stage

    Not phased

    Ages

    18 to 89

    Site

    Shirley Ryan AbilityLab, Chicago, Illinois

    Run by

    Shirley Ryan AbilityLab

    See if you can join NCT07061691 on ClinicalTrials.gov

16. Use of 4D-ICE in Conjunction With TEE for Left Atrial Appendage Closure

    This is a prospective, single center, non-randomized study with two parallel arms intended to study if 4D Intracardiac echocardiography (4D-ICE) (Nuvision, Nuvera TM) will provide better visualization of the anatomical landmarks from the larger imaging volume and provide optimal intra procedural gu…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Kansas City Heart Rhythm Institute - Roe Clinic, Overland Park, Kansas

    Run by

    Kansas City Heart Rhythm Research Foundation

    See if you can join NCT06061757 on ClinicalTrials.gov

17. EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke

    The purpose of this study is to develop and test if upper limb task practice and muscle activity training improve upper limb function in stroke survivors. Participants will be asked to come to the laboratory 23 times (approximately 3 times a week) over 2.5 months to receive upper limb task practice…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina

    Run by

    VA Office of Research and Development

    See if you can join NCT05628324 on ClinicalTrials.gov

18. Fueling Strong Hearts for a Strong South Carolina

    South Carolina is home to many survivors of stroke. After leaving the hospital and finishing therapies, stroke survivors often do not have the supports they need to fully recover. Many live with problems for a long time after their stroke, such as trouble walking or doing everyday tasks like cleani…

    Stage

    Not phased

    Ages

    45 to 80

    Site

    Pee Dee Research and Education Center, Florence, South Carolina

    Run by

    Clemson University

    See if you can join NCT07140952 on ClinicalTrials.gov

19. Spinal Stimulation and Mobility Devices

    This research study will combine non-invasive spinal stimulation with mobility devices to examine the acute impact of the individual and combined effects of these innovative techniques on mobility in children with cerebral palsy.

    Stage

    Not phased

    Ages

    4 to 70

    Site

    University of Washington, Seattle, Washington

    Run by

    University of Washington

    See if you can join NCT05520359 on ClinicalTrials.gov

20. Q Therapeutic System for Chronic Stroke Recovery

    Evaluate the effectiveness of the Q Therapeutic (BQ 3.0) System for individuals with chronic stroke in improving upper extremity function as determined by change in functional outcome measures after 3-month treatment, including in-clinic and at-home sessions.

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Burke Rehabilitation Hospital, White Plains, New York

    Run by

    Burke Rehabilitation Hospital

    See if you can join NCT06979466 on ClinicalTrials.gov

21. Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke

    Our proposed study, "NEUROBALANCE Stroke,"; aims to evaluate the effectiveness of a combined intervention involving robotic balance training and noninvasive brain stimulation in improving balance function and postural control in individuals with chronic stroke. The study will recruit 45 participant…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    Kessler Foundation, West Orange, New Jersey

    Run by

    Kessler Foundation

    See if you can join NCT07113041 on ClinicalTrials.gov

22. To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors

    The goal of this clinical trial is to test a gait (walking) training program in non-ambulatory (unable to walk) chronic stroke survivors. The main question it aims to answer is: • Will gait training improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a sitting l…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT06247553 on ClinicalTrials.gov

23. Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

    This prospective, randomized study aims to comprehensively evaluate the impact of cranioplasty timing on postoperative complications and long-term functional outcomes following decompressive hemicraniectomy (DHC). The primary endpoint focuses on comparing the rates of various postoperative complica…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Thomas Jefferson University Hospitals, Philadelphia, Pennsylvania

    Run by

    Thomas Jefferson University

    See if you can join NCT06632587 on ClinicalTrials.gov

24. Deconstructing Post Stroke Hemiparesis

    TRACTs (DeconsTructing Post StRoke HemipAresis for PreCision NeurorehabiliTation) is a single timepoint study that aims to deconstruct post-stroke deficits of the upper extremity into distinct components and relate these components to brain anatomy and physiology.

    Stage

    Not phased

    Ages

    18 to 90

    Site

    Providence VA Medical Center, Providence, Rhode Island

    Run by

    Providence VA Medical Center

    See if you can join NCT05993221 on ClinicalTrials.gov

25. Constraint Induced Movement Therapy for Walking in Individuals Post Stroke

    To compare the effect of constraint induced movement therapy (CIMT) vs. treadmill training only on walking function in individuals post-stroke, a 6 week, single-blind, randomized training study will be conducted with three assessments of gait to determine the training effect. Subjects will be rando…

    Stage

    Not phased

    Ages

    21 to 75

    Site

    Abilitylab, Chicago, Illinois

    Run by

    Shirley Ryan AbilityLab

    See if you can join NCT03264261 on ClinicalTrials.gov