Cancer Clinical Trials

247 studies are recruiting for cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

   Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve…

   Stage

   Phase 2

   Ages

   2 to 99

   Site

   University of California, San Francisco, San Francisco, California

   Locations

   6 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT05783323 on ClinicalTrials.gov

2. Galleri® in the Medicare Population.

   This multi-center comparative prospective cohort study is designed to assess the real world clinical impact, including safety and test performance, of Galleri®, a blood-based multi-cancer early detection (MCED) test. The study will seek enrollment that is representative of the Medicare population.

   Stage

   Not phased

   Ages

   50 and older

   Site

   Mercy Health - Fort Smith, Fort Smith, Arkansas

   Locations

   72 in total

   Run by

   GRAIL, Inc.

   See if you can join NCT05673018 on ClinicalTrials.gov

3. Evaluation of Late Effects and Natural History of Disease in Patients Treated With Radiotherapy

   BACKGROUND * This protocol acknowledges that it is in the interest of the NIH and ROB, as well as our participants, to continue to follow those who have been treated with radiotherapy at ROB and are not otherwise eligible for current active research protocols. * It also provides a mechanism for the…

   Stage

   Not phased

   Ages

   18 to 120

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT00026650 on ClinicalTrials.gov

4. INTERogating Cancer for Etiology, Prevention and Therapy Navigation

   This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients with cancer. Cancer genetic testing is a series of tests that finds specific changes in cancer cells a…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Arizona, Scottsdale, Arizona

   Locations

   5 in total

   Run by

   Mayo Clinic

   See if you can join NCT06008392 on ClinicalTrials.gov

5. MCW Master Predict (Profile Related Evidence Determining Individualized Cancer Therapy)

   The study is an observational trial for patients undergoing cancer-related interventions and therapy at Medical College of Wisconsin Cancer Center. Projects under this protocol will use patient data that will be collected both retrospectively and prospectively. It will also enable prospective sampl…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin

   Run by

   Sameem M. Abedin, MD

   See if you can join NCT05802069 on ClinicalTrials.gov

6. A Study of Music Therapy for Anxiety in People With Cancer

   The researchers are doing this study to compare two different music-based treatment approaches and see if one may work better to reduce anxiety. The researchers will also study whether these music-based treatment approaches help people feel socially connected and change how they cope with anxiety, …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Memorial Sloan Kettering Basking Ridge (All protocol activities), Basking Ridge, New Jersey

   Locations

   7 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT07845422 on ClinicalTrials.gov

7. FOG-001 in Locally Advanced or Metastatic Solid Tumors

   The goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in participants with familial adenomatous polyposis (FAP).

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Mayo Clinic, Phoenix, Arizona

   Locations

   33 in total

   Run by

   Parabilis Medicines, Inc.

   See if you can join NCT05919264 on ClinicalTrials.gov

8. Study of a Support Program for Quality of Life in Chinese Cancer Patients and Survivors

   The purpose of this study is to evaluate different combinations of cancer education sessions, counseling sessions, and peer support meetings developed for Chinese cancer patients and survivors. The researchers will look at whether the combinations are practical and effective, and how they impact pa…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Memorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge, New Jersey

   Locations

   7 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT07454330 on ClinicalTrials.gov

9. Validation of the Screen of Cancer Survivorship - Occupational Therapy Services (SOCS-OTS) Tool for Use in a Physical Medicine Rehabilitation Clinic

   To compare the results of the SOCS-OTS to another standardized screening measure that is currently being used by rehabilitation services at MD Anderson Cancer Center and to ensure that the SOCS-OTS correctly identifies those individuals needing OT services in cancer care.

   Stage

   Not phased

   Ages

   18 and older

   Site

   MD Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT06329531 on ClinicalTrials.gov

10. Autoimmunity After Checkpoint Blockade

    The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity. Specifically, we wish to understand the genetics and immune system features that cause a subset of cancer patients treated with checkpoint …

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Pennsylvania - Abramson Cancer Center, Philadelphia, Pennsylvania

    Run by

    Abramson Cancer Center at Penn Medicine

    See if you can join NCT04119713 on ClinicalTrials.gov

11. Feasibility of a Real-world, Financial Psycho-oncology Intervention to Address Cancer-related Financial Distress

    The goal of this pilot, feasibility study is to evaluate the feasibility and preliminary impact of a finance-specific psycho-oncology intervention, as well as to explore perceptions of and experiences with this financial psycho-oncology intervention for patients with cancer experiencing financial h…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT07724041 on ClinicalTrials.gov

12. Daily Hand-Held Vibration Therapy

    The purpose of this pilot study is to determine the safety and feasibility of a daily 3-minute hand-held vibration therapy intervention to reduce the severity of CIPN in the hands. The investigators hypothesize that daily vibration therapy can reduce the severity of patient's CIPN in their hands an…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Indiana University Health West, Avon, Indiana

    Locations

    3 in total

    Run by

    Indiana University

    See if you can join NCT04207437 on ClinicalTrials.gov

13. TREC@TAMU Cancer Prevention Registry and Repository

    This study collects health and genetic information to implement cancer prevention and treatment strategies.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Texas A&M Family Care, Bryan, Texas

    Run by

    Texas A&M University

    See if you can join NCT06826014 on ClinicalTrials.gov

14. Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

    This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 …

    Stage

    Not phased

    Ages

    20 to 89

    Site

    Allegheny General Hospital, Pittsburgh, Pennsylvania

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT07023887 on ClinicalTrials.gov

15. A Pilot Study Assessing Myokines During an EXErcise Regimen After Treatment for Breast Cancer

    In this pilot study, the investigators will assess the changes in myokine production based on several different exercise regimens.

    Stage

    Not phased

    Ages

    20 to 89

    Site

    Allegheny General Hospital, Pittsburgh, Pennsylvania

    Locations

    2 in total

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT07698314 on ClinicalTrials.gov

16. EXERT-BC Protein: Protein Supplementation to Improve Body Composition After Treatment for Breast Cancer

    In this study, the investigators hypothesize that a high dose of post-workout protein after each exercise session will have greater improvements in changes in body composition, including muscle mass and percent body fat versus a workout alone.

    Stage

    Not phased

    Ages

    20 to 89

    Site

    AHN Allegheny General Hospital, Pittsburgh, Pennsylvania

    Locations

    2 in total

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT07704476 on ClinicalTrials.gov

17. Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

    The goal of this research study is to measure changes in patients' quality of life after surgeries that affect the facial nerve, including nerve transfer as treatment for facial paralysis.

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Texas M. D. Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT06667427 on ClinicalTrials.gov

18. SAFE.AI: Developing and Testing an AI-based Hybrid Chatbot for Financial Empowerment in Rural Cancer Care

    This is a randomized, two-arm, parallel-group pilot trial investigating a new chatbot tool designed to support cancer patients and caregivers, particularly those in rural communities. Approximately 60 participants will be randomized 1:1 to interact with either a hybrid chatbot or an AI-enabled chat…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Huntsman Cancer Institute/ University of Utah, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT07410689 on ClinicalTrials.gov

19. A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer

    The goal of this clinical trial is to learn if a tailored intervention can help make it easier for adolescents and young adults with cancer to take their medications. The main questions the researchers are trying to answer are: * Does the tailored intervention increase adherence? * Does the tailore…

    Stage

    Not phased

    Ages

    15 to 24

    Site

    Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

    Locations

    4 in total

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT07223463 on ClinicalTrials.gov

20. Prospective Study to Assess a Diagnostic Aid for Cancer

    The primary objective of this study is to establish the performance of two blood-based diagnostic aid test for cancer detection in individuals presenting with symptoms, signs, or findings suggestive of cancer.

    Stage

    Not phased

    Ages

    45 and older

    Site

    Southern California Research Center, Coronado, California

    Locations

    42 in total

    Run by

    Harbinger Health

    See if you can join NCT07046260 on ClinicalTrials.gov

21. Perceptions of Hospital Care at Home for Patients With Cancer: A Qualitative Study of Cancer Providers, Patients and Caregivers.

    The objective of this qualitative research study is to assess the knowledge, attitudes and beliefs of cancer care providers, patients with cancer and caregivers regarding hospital care at home. We aim to conduct qualitative interviews to inform implementation of future on oncology hospital care at …

    Stage

    Not phased

    Ages

    18 and older

    Site

    M D Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT05694650 on ClinicalTrials.gov

22. Support for Bereaved Cancer Caregivers

    Friend and family caregivers of recently deceased cancer patients experience acute bereavement following the death. Post death bereavement is an intense period of mourning that includes an unfolding of the grief process and is characterized by strong emotions and demands on cognitive resources to t…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Michigan State University College of Nursing, East Lansing, Michigan

    Run by

    Michigan State University

    See if you can join NCT06662409 on ClinicalTrials.gov

23. ACTIVATE: AI-driven Clinical-trial Trial-Information and Viability Assessment Tool for EHRs

    This study aims to develop and evaluate ACTIVATE, an AI-driven tool for clinical trial information and viability assessment using electronic health records (EHRs). The project will leverage retrospective and prospective EHR data to build and validate algorithms that identify potentially eligible pa…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dana-Farber Cancer Institute, Boston, Massachusetts

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT07232043 on ClinicalTrials.gov

24. Statins to Prevent Cancer Associated Blood Clots

    Patients with cancer are at high risk for life-threatening venous thromboembolism (VTE) yet rarely receive anticoagulant prophylaxis due to bleeding risks. Thus, effective prophylaxis in oncology requires a method to reduce VTE without increasing hemorrhage. The primary aim of the Statin Therapy to…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    City of Hope, Irvine, California

    Locations

    9 in total

    Run by

    Brigham and Women's Hospital

    See if you can join NCT07303816 on ClinicalTrials.gov

25. Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT

    Cancer-related fatigue (CRF) is a significant problem for cancer patients. This prospective, basic science, observational study will evaluate for changes in CRF associated with molecular characteristics prior to, during, and at the completion of non-investigational, standard-of-care, combined chemo…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of California, San Francisco, San Francisco, California

    Run by

    University of California, San Francisco

    See if you can join NCT06633224 on ClinicalTrials.gov