HIV Clinical Trials

101 studies are recruiting for hiv in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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By city

Boston, Massachusetts 14 San Francisco, California 12 Bethesda, Maryland 10 Birmingham, Alabama 9 Miami, Florida 9 Baltimore, Maryland 8 Chicago, Illinois 7 Philadelphia, Pennsylvania 7 Atlanta, Georgia 6 New Haven, Connecticut 6 New York, New York 6 Houston, Texas 5 Decatur, Georgia 4 Orlando, Florida 4 Pittsburgh, Pennsylvania 4 Providence, Rhode Island 4 San Diego, California 4 Washington D.C., District of Columbia 4 Dallas, Texas 3 Jacksonville, Florida 3 Nashville, Tennessee 3 Winston-Salem, North Carolina 3

Studies, page 4

  1. Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

    The goal of this study is to determine the feasibility and impact of delivering long-acting injectable cabotegravir HIV pre-exposure prophylaxis and suite of support services to adults who inject non-prescription drugs who are risk for HIV through known sexual risk.

    Stage
    Phase 4
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    2 in total
    Run by
    Massachusetts General Hospital

    See if you can join NCT07199335 on ClinicalTrials.gov

  2. Proof-of-concept of a Behavioral Intervention to Improve the Cardiovascular Health of People Living With HIV

    Heart failure (HF) is a growing health and economic burden around the globe, and it remains a leading cause of morbidity and mortality among the general population. HIV is recognized as an independent risk factor for HF, due to direct and indirect effects. Furthermore, people living with HIV (PLWH)…

    Stage
    Not phased
    Ages
    40 and older
    Site
    University of Washington, Seattle, Washington
    Locations
    2 in total
    Run by
    University of Washington

    See if you can join NCT07105007 on ClinicalTrials.gov

  3. Multidisciplinary Low-Barrier and Mobile HIV Care to Improve Retention and Viral Suppression: Stakeholder-Engaged Design and Evaluation

    The purpose of this study is to evaluate the implementation and effectiveness of a flexible, multidisciplinary, integrated drop-in/mobile HIV care approach for people living with HIV (PLH) who are not well engaged in current care systems (i.e. scheduled HIV primary care visits). The hybrid type 2 i…

    Stage
    Not phased
    Ages
    15 and older
    Site
    La Clinica de la Raza, Inc, Oakland, California
    Locations
    5 in total
    Run by
    University of California, San Francisco

    See if you can join NCT05887557 on ClinicalTrials.gov

  4. Improving HIV Care Continuum Outcomes Among Formerly Incarcerated Individuals Through Critical Time Legal Interventions

    The purpose of this research is to better understand the impact of receiving legal aid on HIV care continuum outcomes among formerly incarcerated individuals. In addition, the investigators would like to assess the effectiveness of a comprehensive training for providers in increasing knowledge abou…

    Stage
    Not phased
    Ages
    18 to 100
    Site
    University of Central Florida, Orlando, Florida
    Run by
    University of Central Florida

    See if you can join NCT06171919 on ClinicalTrials.gov

  5. PrOTECT AL: PrEP Optimization Through Enhanced Continuum Tracking

    The purpose of this study is to enhance and evaluate the implementation of a PrEP Care Continuum data dashboard across seven distinct clinical sites in Alabama. By leveraging real-time data and fostering collaborative partnerships, this project aims to accurately visualize care disparities, allocat…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Alabama at Birmingham, Birmingham, Alabama
    Run by
    University of Alabama at Birmingham

    See if you can join NCT07231640 on ClinicalTrials.gov

  6. Alcohol Research in HIV: Relapse Prevention

    3-arm type 1 pilot implementation-efficacy trial for people with alcohol use disorders to examine the preliminary effectiveness and feasibility of an adapted 2-session, computerized and person delivered relapse prevention intervention.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Johns Hopkins School of Medicine, Baltimore, Maryland
    Run by
    Johns Hopkins University

    See if you can join NCT05163301 on ClinicalTrials.gov

  7. HIV, Equity, and Addiction Training (HEAT) Program

    This project is a pilot study to determine the feasibility and acceptability of a telemedicine intervention for substance use disorder service delivery in diverse people living with HIV in Alabama.

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Alabama at Birmingham, Birmingham, Alabama
    Run by
    University of Alabama at Birmingham

    See if you can join NCT06370481 on ClinicalTrials.gov

  8. ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services

    While there has been a significant increase in the uptake of antiretroviral therapy among women living with HIV (WLHIV) in many low- and-middle income countries (LMICs), the coverage of cervical cancer screening and treatment (CCST) among WLHIV remains low. This study aims to leverage the available…

    Stage
    Not phased
    Ages
    25 to 64
    Site
    UC San Diego, La Jolla, California
    Locations
    2 in total
    Run by
    University of California, San Diego

    See if you can join NCT06128304 on ClinicalTrials.gov

  9. The DC Cohort Longitudinal HIV Status Neutral Study

    The goal of the DC Cohort is to establish a clinic-based city-wide longitudinal cohort that will describe clinical outcomes, and improve the quality of care for patients diagnosed with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) or at higher risk for acquiring HIV an…

    Stage
    Not phased
    Ages
    Any age
    Site
    Kaiser Permanente Mid-Atlantic States, Washington D.C., District of Columbia
    Locations
    14 in total
    Run by
    George Washington University

    See if you can join NCT01206920 on ClinicalTrials.gov

  10. Prevention Ambassadors: Intervention to Promote HIV Service Engagement in the Networks of SSP Clients

    HIV testing and service uptake are infrequent among people who use drugs (PWUD) in the United States. In partnership with a community-based syringe service program (SSP), this project will develop the SSP-based "Prevention Ambassadors" (PA) intervention to promote HIV testing and service uptake amo…

    Stage
    Not phased
    Ages
    18 and older
    Site
    San Diego State University, San Diego, California
    Run by
    San Diego State University

    See if you can join NCT06848686 on ClinicalTrials.gov

  11. HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

    The focus of this pilot will be on falls and neurocognitive symptoms, and the impact of alcohol, cannabis use, and medications on these outcomes. The rationale is that alcohol use at any level may interact with neurocognitively active medications, alcohol, and cannabis use leading to falls and impa…

    Stage
    Phase 1
    Ages
    50 and older
    Site
    VA Connecticut Healthcare System, West Haven, Connecticut
    Run by
    Yale University

    See if you can join NCT06513819 on ClinicalTrials.gov

  12. HIV Suicide Prevention With AI-DBT

    One in four older persons living with HIV/AIDS (PLWHA) report at least one suicide attempt in their lifetime, and the risk for death by suicide is 100 times higher in PLWHA than in the general population. Currently, there are no behavioral interventions that specifically address suicide prevention …

    Stage
    Not phased
    Ages
    50 and older
    Site
    New Jersey Community Research Initiative, Newark, New Jersey
    Locations
    2 in total
    Run by
    Rutgers, The State University of New Jersey

    See if you can join NCT07339189 on ClinicalTrials.gov

  13. Optimizing Tobacco Treatment Delivery for People Living With HIV

    The purpose of this study is to conduct a randomized trial to evaluate a proactive, opt-out model of provider contact to deliver smoking cessation support for people living with HIV compared to standard care support delivered through traditional clinic pathways. Investigators will also evaluate imp…

    Stage
    Not phased
    Ages
    21 and older
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Run by
    Medical University of South Carolina

    See if you can join NCT05019495 on ClinicalTrials.gov

  14. Universal Basic Income and Structural Racism in the US South: HIV Care

    Universal Basic Income (UBI) is a promising strategy aimed at recalibrating economic systems that are grounded in structural racism. Black men have long been the target of oppressive and interconnected systems of finance and healthcare access, leading to a disproportionate burden of exposure to inf…

    Stage
    Not phased
    Ages
    25 and older
    Site
    University of Arkansas for Medical Sciences, Little Rock, Arkansas
    Run by
    University of Arkansas

    See if you can join NCT06186128 on ClinicalTrials.gov

  15. PrEP Intervention in Prince George's County, Maryland

    The goal of the proposed research is to design a peer-based community intervention focused on addressing HIV stigma, and peer support to increase PrEP initiation in Prince George's County, MD. Participants will attend intervention events focused on stigma reduction and building community. Researche…

    Stage
    Not phased
    Ages
    18 and older
    Site
    George Mason University, Fairfax, Virginia
    Run by
    George Mason University

    See if you can join NCT06141408 on ClinicalTrials.gov

  16. Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health

    This is a partially randomized, open-label phase 1 study to evaluate the safety and immunogenicity of a priming regimen of 426c.Mod.Core-C4b adjuvanted with 3M-052 AF + Alum followed by boosts with HxB2.WT.Core-C4b adjuvanted with 3M-052 AF + Alum. The primary hypothesis is that the boosting with H…

    Stage
    Phase 1
    Ages
    18 to 55
    Site
    The Hope Clinic of the Emory Vaccine Research Center; Emory University, Decatur, Georgia
    Locations
    6 in total
    Run by
    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT06796686 on ClinicalTrials.gov

  17. Testing Two Interventions to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV

    Engagement in HIV medical care and adherence to HIV medications are both essential in improving health outcomes among people living with HIV (PLH), but PLH living in rural areas-who suffer higher mortality rates than their urban counterparts-can confront multiple barriers to care engagement and adh…

    Stage
    Not phased
    Ages
    50 and older
    Site
    Center for AIDS Intervention Research, Medical College of Wisconsin, Milwaukee, Wisconsin
    Run by
    Medical College of Wisconsin

    See if you can join NCT06269081 on ClinicalTrials.gov

  18. Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV

    Older people with HIV (OPWH) are disproportionately impacted by cardiovascular disease (CVD) attributable to behavioral risk factors, and chronic HIV immune dysregulation resulting inflammation. Systemic inflammation is exacerbated by psychological distress via activating the immune response and dr…

    Stage
    Not phased
    Ages
    50 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT06001814 on ClinicalTrials.gov

  19. Striving Towards EmPowerment and Medication Adherence R01

    This is a study for Black women living with HIV to test a counseling program for Black women living with HIV. This participant may be a good fit if the participant is a Black woman, living with HIV, has a history of trauma, and is currently taking Antiretroviral Therapy (ART) medicines

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Miami, Miami, Florida
    Run by
    University of Miami

    See if you can join NCT06463886 on ClinicalTrials.gov

  20. Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV

    This study will determine the effects of pregnenolone on brain function, inflammation and depressive symptoms in people with HIV who have depression. Participants in this study will receive a pill of either pregnenolone or placebo, and can stay on their current antidepression medications. Brain ima…

    Stage
    Phase 2
    Ages
    18 to 85
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT05570812 on ClinicalTrials.gov

  21. Wellness Intervention for Smoking and HIV

    The investigators propose to use a parallel group, randomized controlled trial to test the efficacy of a 13-week personalized approach to reducing smoking intervention versus a second approach using a different health intervention on smoking cessation, healthy sleep metrics, and biomarkers of cardi…

    Stage
    Not phased
    Ages
    18 to 75
    Site
    Banner University Medical Center Phoenix, Phoenix, Arizona
    Locations
    2 in total
    Run by
    University of Arizona

    See if you can join NCT04725617 on ClinicalTrials.gov

  22. Text Education About Cardiovascular Health and HIV (TEACH-HIV)

    The overall objective is to evaluate the efficacy of educational text messages to reduce cardiovascular risk among persons living with HIV (PLWH).

    Stage
    Not phased
    Ages
    40 and older
    Site
    Zuckerberg San Francisco General Hospital, San Francisco, California
    Locations
    2 in total
    Run by
    University of California, San Francisco

    See if you can join NCT05642858 on ClinicalTrials.gov

  23. Predictors of Health Service Utilizations Among Key Population in Washington DC

    The primary objective of the proposed study is to investigate how PrEP use might result in an increase in the utilization of health and social services offered at a local community-based organization. Our primary hypothesis is that the investigators will observe higher utilization of sexual health …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Us Helping Us, People into Living Inc, Washington D.C., District of Columbia
    Run by
    Us Helping Us, People Into Living, Inc.

    See if you can join NCT06046079 on ClinicalTrials.gov

  24. HIV Prevention Intervention for Latino Male Couples

    The primary objective of this proposal is to test the efficacy of Connecting Latinxs en Pareja (CLP). CLP is a four-session intervention grounded in social cognitive theory and a relationship oriented ecological framework. The investigators will examine whether participants assigned to CLP report a…

    Stage
    Not phased
    Ages
    18 to 100
    Site
    University of Central Florida, Orlando, Florida
    Run by
    University of Central Florida

    See if you can join NCT06131931 on ClinicalTrials.gov

  25. Economic Navigation and Strengthening to Research Unrestricted Services for Transgender Women (ENTRUST)

    The overall hypothesis is that stabilizing transgender women financially while providing them tailored counselling will increase their odds of them linking to substance use services, PrEP services if they do not have HIV, and transgender women who are living with HIV will be more adherent to their …

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Central Florida, Orlando, Florida
    Run by
    University of Central Florida

    See if you can join NCT06202898 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.