HIV Clinical Trials in Philadelphia, Pennsylvania

7 studies are recruiting for hiv in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies

   This phase 1 study will evaluate the safety, tolerability, and immune responses of two experimental mRNA HIV vaccines in adults living with HIV who are in overall good health. The study will enroll about 42 participants at multiple study sites. Researchers will assess whether these vaccines can sta…

   Stage

   Phase 1

   Ages

   18 to 60

   Site

   Penn Prevention CRS (Site#: 30310), Philadelphia, Pennsylvania

   Locations

   16 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT07569029 on ClinicalTrials.gov

2. A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

   This study is testing a lab-made antibody called ePGT121v1-LS that targets a specific part of HIV. Researchers will give it by vein (IV) and under the skin (SC), both on its own and together with two other antibodies, VRC07-523LS and PGDM1400LS, which target different parts of the virus. They will …

   Stage

   Phase 1

   Ages

   18 to 55

   Site

   Penn Prevention CRS (Site ID: 30310), Philadelphia, Pennsylvania

   Locations

   11 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT07390955 on ClinicalTrials.gov

3. Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships

   The goal of this study is to learn if STEP-UP (Streamlining Telehealth for Expanded PrEP Utilization through community Partnerships) works to expand access to PrEP for people who could benefit from HIV prevention tools. STEP-UP is an innovative model for PrEP delivery that positions community-based…

   Stage

   Not phased

   Ages

   16 and older

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT07246057 on ClinicalTrials.gov

4. Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV

   This is a phase 1, multicenter, open-label, dose escalation, first-in-human (FIH) trial to evaluate the safety and immunogenicity of DV201P-RNA and DV202B1-RNA, immunogens designed to induce HIV-1 envelope (Env) V2 apex-specific broadly neutralizing antibodies (V2 apex bnAbs). Both vaccines consist…

   Stage

   Phase 1

   Ages

   18 to 55

   Site

   Penn Prevention CRS (Site ID 30310), Philadelphia, Pennsylvania

   Locations

   7 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT07390474 on ClinicalTrials.gov

5. Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

   This research is being done to better understand rejection in transplant recipients with HIV who receive kidneys from donors with vs without HIV.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   18 in total

   Run by

   Johns Hopkins University

   See if you can join NCT06263426 on ClinicalTrials.gov

6. The Collaborative Care PrTNER Study

   A randomized controlled trial to assess the ability of a Collaborative Care Prevention, Treatment, Navigation, Engagement, Resource (PrTNER) intervention to increase initiation of preexposure prophylaxis (PrEP) (for those at-risk for HIV) and decrease viral load (for those living with HIV) among yo…

   Stage

   Not phased

   Ages

   15 to 29

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   2 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT06585631 on ClinicalTrials.gov

7. Transitional Housing and HIV Health

   The goal of this pilot study is to evaluate the implementation and outcomes of the Arms Around You (AAY) program, a supportive housing initiative launched by the Philadelphia Department of Public Health (PDPH) in 2024. The program aims to address housing instability among people with HIV (PWH) usin…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   2 in total

   Run by

   University of Pennsylvania

   See if you can join NCT06829394 on ClinicalTrials.gov