HIV Clinical Trials

104 studies are recruiting for hiv in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults

   The use of behavioral intervention to reduce stimulant use and concurrent HIV sexual transmission risk.

   Stage

   Not phased

   Ages

   16 to 24

   Site

   University of California, Los Angeles, Los Angeles, California

   Locations

   2 in total

   Run by

   Westat

   See if you can join NCT06444360 on ClinicalTrials.gov

2. Olfactory Function and Model-Based Behavior in People Living With HIV and SUD

   Background: Human immunodeficiency virus (HIV) infection can affect areas of the brain that control thinking ability. These same areas of the brain also control the sense of smell. HIV infection is common in people with substance use disorder (SUD). SUD also affects thinking ability. Researchers wa…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   National Institute on Drug Abuse, Baltimore, Maryland

   Run by

   National Institute on Drug Abuse (NIDA)

   See if you can join NCT07637669 on ClinicalTrials.gov

3. Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV

   We are studying virologic and/or immunologic parameters of HIV infection and other infectious or non-infectious immune deficiency diseases in order to better understand the pathogenesis of HIV. Because of the lack of an adequate animal model it is generally necessary to utilize human peripheral blo…

   Stage

   Not phased

   Ages

   18 to 120

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Locations

   2 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT00001281 on ClinicalTrials.gov

4. Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV Infection

   This study will investigate HIV infection and associated conditions by monitoring infected patients. The study will also serve as a means for recruiting HIV-infected individuals to NIAIDs ongoing clinical and laboratory studies and supporting the institute s infectious disease training program by p…

   Stage

   Not phased

   Ages

   18 and older

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT00789009 on ClinicalTrials.gov

5. HIV/HBV/HCV Triple Screening in Primary Care

   Design: This will be a within-subjects repeated-measures design, testing an electronic medical record pop-up alert linked to order panels for screening blood tests for human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). Study participants will be primary care p…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Texas Southwestern Medical Center, Dallas, Texas

   Run by

   University of Texas Southwestern Medical Center

   See if you can join NCT07031219 on ClinicalTrials.gov

6. Leukapheresis to Obtain Plasma or Lymphocytes for Studies of HIV-infected Patients, Including Long-term Non-progressors

   This study will collect white blood cells and plasma for research on how the immune system controls HIV infection. The immune system of a very small group of people with HIV, called non-progressors, has been able to control HIV for long periods without antiretroviral therapy. Some immune system-rel…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT00029445 on ClinicalTrials.gov

7. Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naive HIV-1 Research Participants

   There is evidence that early and aggressive treatment with antiretroviral drugs can prevent the loss of immune cell function that accompanies HIV infection. This study will use leukapheresis (drawing blood, separating out the white cells and returning the blood to the patient) to obtain blood cells…

   Stage

   Not phased

   Ages

   18 to 120

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT00039689 on ClinicalTrials.gov

8. HEME-25 Open-Label Feasibility Study of Elranatamab Utilized as Consolidation in Newly Diagnosed Plasmablastic Lymphoma With or Without HIV

   This is a single-arm feasibility trial in which patients with histologically confirmed plasmablastic lymphoma (PBL) with or without HIV, who have achieved a Complete Response or Partial Response after definitive frontline chemotherapy, will receive Elranatamab (Elra) consolidation.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   University of Illinois at Chicago, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT07647432 on ClinicalTrials.gov

9. Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy Adults

   This Phase 1 study will evaluate the safety, tolerability, and immune responses of investigational CH505 HIV vaccine regimens in adults in overall good health without HIV. Participants will receive CH505 protein nanoparticle vaccines (DV901-NP) formulated with the investigational adjuvant ACU-026-0…

   Stage

   Phase 1

   Ages

   18 to 55

   Site

   Brigham and Women's Hospital Vaccine CRS (BWH VCRS) Site# 30007, Boston, Massachusetts

   Locations

   8 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT07757802 on ClinicalTrials.gov

10. Viral Load in Blood and Lymph Tissues in People Living With HIV

    This is a study to determine the effect of the human immunodeficiency virus (HIV) on lymphoid tissues (e.g., lymph nodes) as compared to peripheral white blood cells. We have shown in previous studies that the lymph node is a major site of accumulation of HIV in the body, as well as being a site wh…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT00001316 on ClinicalTrials.gov

11. Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

    BACKGROUND: * A number of important scientific advances can be made through the study of blood, bone marrow, tumor, or other tissue samples from patients with HIV infection, infection with Kaposi s sarcoma associated herpesvirus (KSHV), infection with other oncogenic viruses, or cancer. * This prot…

    Stage

    Not phased

    Ages

    18 to 120

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Cancer Institute (NCI)

    See if you can join NCT00006518 on ClinicalTrials.gov

12. Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

    Background: People living with HIV(PLWH) are at a higher risk for cancers that may be curable with a bone marrow transplant. HIV infection itself is no longer a reason to not get a transplant, for patients who otherwise have a standard reason to need transplant. Objective: This study is being done …

    Stage

    Phase 1

    Ages

    12 to 120

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Cancer Institute (NCI)

    See if you can join NCT05470491 on ClinicalTrials.gov

13. Natural History Study of Kaposi Sarcoma

    Background: Kaposi sarcoma (KS) is a type of tumor caused by the Kaposi sarcoma herpesvirus. KS usually affects the skin, but lesions can also appear in the lymph nodes, lungs and digestive tract. KS is most common in people with compromised immunity, but it also appears in otherwise healthy people…

    Stage

    Not phased

    Ages

    18 to 120

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Cancer Institute (NCI)

    See if you can join NCT06375122 on ClinicalTrials.gov

14. Linking Youth to Pre-Exposure Prophylaxis (PrEP) Services

    The LYPS intervention is a multi-level intervention that combines: a) structural-level delivery of PrEP and PrEP services by a community health professional (CHP) at a designated place in the community being offered by the SC where PrEP is not yet provided (e.g., participant's home, community partn…

    Stage

    Not phased

    Ages

    13 to 24

    Site

    San Francisco Department of Public Health, San Francisco, California

    Locations

    4 in total

    Run by

    Westat

    See if you can join NCT07438041 on ClinicalTrials.gov

15. Striving Towards EmPowerment and Medication Adherence R01

    This is a study for Black women living with HIV to test a counseling program for Black women living with HIV. This participant may be a good fit if the participant is a Black woman, living with HIV, has a history of trauma, and is currently taking Antiretroviral Therapy (ART) medicines

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Miami, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT06463886 on ClinicalTrials.gov

16. Combatting HIV Or Other STIs Early (CHOOSE)

    The overarching goal of this project is to optimize the PrEP Choice integrated mHealth package and assess the efficacy and cost of PrEP Choice on PrEP initiation and adherence among young people. It is hypothesized that PrEP Choice will improve HIV PrEP uptake and adherence among young people and w…

    Stage

    Not phased

    Ages

    13 to 24

    Site

    San Francisco Department of Public Health, San Francisco, California

    Locations

    6 in total

    Run by

    Westat

    See if you can join NCT07510048 on ClinicalTrials.gov

17. Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

    Background: Human immunodeficiency virus (HIV) infects CD4 T cells. There is no cure for HIV. People with HIV need to take daily medications called antiretroviral therapy (ART) to control their infection. ART stops HIV from infecting cells, but HIV does not go away. Some infected cells remain. If A…

    Stage

    Phase 2

    Ages

    18 to 100

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Cancer Institute (NCI)

    See if you can join NCT05419024 on ClinicalTrials.gov

18. Testing Two Interventions to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV

    Engagement in HIV medical care and adherence to HIV medications are both essential in improving health outcomes among people living with HIV (PLH), but PLH living in rural areas-who suffer higher mortality rates than their urban counterparts-can confront multiple barriers to care engagement and adh…

    Stage

    Not phased

    Ages

    50 and older

    Site

    Center for AIDS Intervention Research, Medical College of Wisconsin, Milwaukee, Wisconsin

    Run by

    Medical College of Wisconsin

    See if you can join NCT06269081 on ClinicalTrials.gov

19. Small Trial of Alendronate Impact on the Reservoir of HIV

    This clinical trial is designed to test the effects of alendronate (ALN) on people living with HIV who are already receiving antiretroviral therapy (ART). Participants are randomly assigned in a 2:1 ratio to either receive alendronate or a placebo, and neither the participants nor the researchers k…

    Stage

    Phase 2

    Ages

    18 to 65

    Site

    University of California, San Francisco HIV/AIDS (Site ID: 801), San Francisco, California

    Locations

    5 in total

    Run by

    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT07216794 on ClinicalTrials.gov

20. Case Management Dyad

    The overall goal of this study is to test whether dyadic and focused case management coupled with contingency management will (1) improve financial wellbeing, (2) improve access to food, (3) increase linkage and retention rates for individuals living with HIV or those taking PrEP (PrEP persistence)…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Chicago, Chicago, Illinois

    Run by

    University of Chicago

    See if you can join NCT06162897 on ClinicalTrials.gov

21. Work2Prevent Plus: Structural Intervention to Promote HIV Care in Black Sexual Minority Men

    The goal of this observational study is to learn about the pilot test of the employment program among young men living with HIV or part of a community highly impacted by HIV. The main question it aims to answer is: What is the feasibility and acceptability of the employment program? Young male part…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Chicago, Chicago, Illinois

    Run by

    University of Chicago

    See if you can join NCT06894199 on ClinicalTrials.gov

22. HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

    The focus of this pilot will be on falls and neurocognitive symptoms, and the impact of alcohol, cannabis use, and medications on these outcomes. The rationale is that alcohol use at any level may interact with neurocognitively active medications, alcohol, and cannabis use leading to falls and impa…

    Stage

    Phase 1

    Ages

    50 and older

    Site

    VA Connecticut Healthcare System, West Haven, Connecticut

    Run by

    Yale University

    See if you can join NCT06513819 on ClinicalTrials.gov

23. A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities

    This study includes testing for four STIs (chlamydia, gonorrhea, syphilis, and HIV) at no cost. If positive, individual subjects will also be counseled and offered options for treatment for themselves and their sex partners that may include no cost expedited treatment and the option to be rescreene…

    Stage

    Not phased

    Ages

    15 to 26

    Site

    Tulane University Celia Scott Weatherhead School of Public Health and Tropical Medicine, New Orleans, Louisiana

    Run by

    Tulane University

    See if you can join NCT06428643 on ClinicalTrials.gov

24. Apheresis to Obtain Plasma or White Blood Cells for Laboratory Studies

    This study will collect blood plasma and white blood cells from individuals using a procedure called apheresis. Apheresis is a method of collecting larger quantities of certain blood components that can safely be collected through a simple blood draw. The blood components will be used in laboratory…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT00114647 on ClinicalTrials.gov

25. A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV

    The goal of this randomized clinical trial is to learn if tai chi/qigong decreases depressive symptoms among older people living with HIV compared to a health education class. The main questions it aims to answer are: Does tai chi/qigong reduce depressive symptoms among older people living with HIV…

    Stage

    Not phased

    Ages

    50 to 75

    Site

    Florida International University, Miami, Florida

    Run by

    Florida International University

    See if you can join NCT06586619 on ClinicalTrials.gov