Breast Cancer Clinical Trials

415 studies are recruiting for breast cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 15

1. Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases

   This is a Phase I/II Study to determine the safety and efficacy of Sacituzumab Govitecan and Zimberelimab with stereotactic radiation (SRS) in participants with metastatic triple negative breast cancer with brain metastases, compared to treatment with Sacituzumab Govitecan alone.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Moffitt Cancer Center, Tampa, Florida

   Run by

   H. Lee Moffitt Cancer Center and Research Institute

   See if you can join NCT06238921 on ClinicalTrials.gov

2. Prospective Breast Cancer Biospecimen Collection

   Tissue will be procured during a standard of care procedure the patient will already be scheduled to undergo. A one time blood draw will be performed at this time and an optional rectal swab for biome analysis may occur. Follow Up will only consist of chart review to determine date of recurrence, m…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania

   Run by

   Thomas Jefferson University

   See if you can join NCT04074720 on ClinicalTrials.gov

3. SAVE Trial: SAfe Opioid Use Video Education

   The study will assess the efficacy of a standardized postoperative patient-centered intervention designed to educate patients on the opioid epidemic, the judicious use of opioids, and the proper disposal of opioids. This trial is a single-institution, randomized controlled trial comparing total pos…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Utah Huntsman Cancer Institute, Salt Lake City, Utah

   Run by

   University of Utah

   See if you can join NCT07044583 on ClinicalTrials.gov

4. Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

   Most physicians still use a one-size-fits-all approach to breast screening in which all women, regardless of their personal history, family history or genetics (except BRCA carriers) are recommended to have annual mammograms starting at age 40. Mammograms benefit women by detecting cancers early wh…

   Stage

   Not phased

   Ages

   30 to 74

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   11 in total

   Run by

   University of California, San Francisco

   See if you can join NCT02620852 on ClinicalTrials.gov

5. BREAST Choice Decision Tool R21 - AIM2

   Breast reconstruction is a critical component of breast cancer treatment because it restores quality of life and body image after mastectomy. However, Spanish-speaking Latina women are significantly less likely to undergo reconstruction (13.5% vs. 41% for non-Latina White or highly acculturated Lat…

   Stage

   Not phased

   Ages

   18 and older

   Site

   The University of North Carolina, Chapel Hill, North Carolina

   Run by

   UNC Lineberger Comprehensive Cancer Center

   See if you can join NCT06817226 on ClinicalTrials.gov

6. Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer

   The goal of this interventional study is to optimize the protocol of FES PET/CT in Estrogen Receptor positive Breast cancer patients with Brain metastases. Patients will undergo MRI of the brain and FDG PET/CT brain as part of standard of care for radiation treatment planning. An additional 18F-FES…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   New York-Presbyterian/Weill Cornell Medical Center, New York, New York

   Run by

   Weill Medical College of Cornell University

   See if you can join NCT06072807 on ClinicalTrials.gov

7. WashU DIEP Flap Video and Patient Understanding Improvement

   Patients will complete a survey before and after watching the WashU DIEP Flap Video at their pre-operative standard of care visit, and a third survey at their post-operative standard of care visit. These surveys will use questions from SILS, APAIS, PEMAT, and AIM/IAM to assess the patient's health …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Washington University School of Medicine, St Louis, Missouri

   Run by

   Washington University School of Medicine

   See if you can join NCT06864754 on ClinicalTrials.gov

8. ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy

   The purpose of this study is to compare any good and bad effects of giving radiation treatment for breast cancer in 3 treatments over about 2 days.

   Stage

   Phase 2

   Ages

   45 to 79

   Site

   Virginia Commonwealth University, Richmond, Virginia

   Run by

   Virginia Commonwealth University

   See if you can join NCT06185205 on ClinicalTrials.gov

9. Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)

   The goal of this study is to learn more about how exercise might lower the risk of developing breast cancer in women with dense breast tissue by studying changes that occur in breast tissue and blood as a result of participating in an exercise program. The names of the study groups in this study ar…

   Stage

   Not phased

   Ages

   18 to 59

   Site

   Dana Farber Cancer Institute, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Dana-Farber Cancer Institute

   See if you can join NCT06322888 on ClinicalTrials.gov

10. Enhancing Mammography Programs for Outreach, Wellness, Education, and Resources (EMPOWER) in Underserved Populations Study

    This study is investigating the feasibility of a digital tool called a chatbot for providing educational information about mammography through a tablet, computer, or phone. This study will recruit participants who recently had a mammogram with the University of Utah. Based on their mammography resu…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Huntsman Cancer Institute/ University of Utah, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT07029490 on ClinicalTrials.gov

11. Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots

    To evaluate a community-based outreach initiative for screening, diagnosis, and treatment of breast, lung, and prostate cancers in underserved adults using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) implementation science framework.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Adventhealth, Orlando, Florida

    Run by

    AdventHealth

    See if you can join NCT07231159 on ClinicalTrials.gov

12. RADIANT: Pre-op Radiation With Abemaciclib and Letrozole

    This phase 1b study investigates the safety and feasibility of combining pre-operative radiation therapy with Cyclin-Dependent Kinase 4 (CDK4/6) inhibitors in participants with hormone receptor positive/HER2 negative (HR+/HER2-) breast cancer. The study aims to assess the benefits of concurrent use…

    Stage

    Phase 1

    Ages

    60 and older

    Site

    RWJBarnabas Health Clara Maas Medical Center, Belleville, New Jersey

    Locations

    4 in total

    Run by

    Mridula George, MD

    See if you can join NCT06139107 on ClinicalTrials.gov

13. Breast Re-irradiation After Second Ipsilateral Lumpectomy

    The purpose of this research study is to test the safety and possible harms of treating breast cancer with reirradiation, after breast surgery. The researchers want to find out what effects (good and bad) reirradiation has on people who have already received radiation before surgery.

    Stage

    Not phased

    Ages

    40 and older

    Site

    Lynn Cancer Institute at Baptist Health, Inc., Boca Raton, Florida

    Locations

    2 in total

    Run by

    Youssef Zeidan

    See if you can join NCT06867484 on ClinicalTrials.gov

14. TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer

    The aim of this study is to assess feasibility of a new imaging technology in the management of breast cancer - Tumor Microenvironment of Metastasis - Magnetic Resonance imaging (TMEM-MRI).

    Stage

    Not phased

    Ages

    18 and older

    Site

    Montefiore Medical Center, The Bronx, New York

    Run by

    Montefiore Medical Center

    See if you can join NCT03694756 on ClinicalTrials.gov

15. Neratinib in Combination With Ruxolitinib in Patients With mTNBC

    The goal of this clinical trial is to assess the safety and efficacy of combined ruxolitinib and neratinib in patients with chemotherapy-pretreated metastatic triple negative breast cancer. This trial will evaluate one dosing schedule of neratinib in ruxolitinib in patients with metTNBC with locore…

    Stage

    EARLY_Phase 1

    Ages

    18 and older

    Site

    Baylor University Medical Center, Baylor Charles A Sammons Cancer Center, Dallas, Texas

    Run by

    Baylor Research Institute

    See if you can join NCT06008275 on ClinicalTrials.gov

16. A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

    The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer.

    Stage

    Phase 3

    Ages

    18 to 75

    Site

    Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey

    Locations

    7 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT06144164 on ClinicalTrials.gov

17. Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks

    The purpose this research is to compare two different standards of care for pain management and two different standards of care for local numbing medicine for breast cancer patients who will have a total mastectomy.

    Stage

    Phase 4

    Ages

    18 and older

    Site

    University of Cincinnati Medical Center, Cincinnati, Ohio

    Run by

    University of Cincinnati

    See if you can join NCT06574022 on ClinicalTrials.gov

18. RAD 1802: Pilot Trial of Five Fraction Stereotactic Body Radiotherapy for Early Stage Breast Cancer Patients Eligible for Post-Operative Accelerated Partial Breast Irradiation (APBI)

    This study offers 5 fractions of radiation treatment through partial breast irradiation in patients with early stage breast cancer after having a lumpectomy.

    Stage

    Not phased

    Ages

    18 to 99

    Site

    University of Alabama at Birmingham (UAB) Hazelrig-Salter Radiation Oncology Center (HSROC), Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT03643861 on ClinicalTrials.gov

19. Lifting More Than Weights: Resistance Exercise Program Across Socioeconomic Groups for Cancer-Related Fatigue Management

    The long-term goal of this project is to improve the implementation of tailored resistance exercise interventions for Appalachian breast cancer survivors. To achieve this goal, the primary objective is to enhance the understanding of how biological, psychological, and social factors interact to inf…

    Stage

    Not phased

    Ages

    18 and older

    Site

    West Virginia University, Morgantown, West Virginia

    Run by

    West Virginia University

    See if you can join NCT06960720 on ClinicalTrials.gov

20. High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer

    The overall goal of this project is to develop an integrative system of breast cancer risk assessment based on epidemiologic and biologic risk variables, as well as to develop or refine risk biomarkers which may be useful in predicting and monitoring response to prevention interventions.

    Stage

    Not phased

    Ages

    30 to 65

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    Carol Fabian, MD

    See if you can join NCT00291096 on ClinicalTrials.gov

21. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical…

    Stage

    Not phased

    Ages

    Any age

    Site

    Massive Bio SYNERGY-AI site, Birmingham, Alabama

    Locations

    68 in total

    Run by

    Massive Bio, Inc.

    See if you can join NCT03452774 on ClinicalTrials.gov

22. Surviving Daily Life

    The primary goal of this project is to evaluate the feasibility of a 14-day mobile daily diary study among racially diverse breast cancer survivors. Further, the investigators will examine the validity and reliability of the daily stress and daily cognitive performance measures among breast cancer …

    Stage

    Not phased

    Ages

    40 and older

    Site

    Thomas Jefferson University, Philadelphia, Pennsylvania

    Run by

    Thomas Jefferson University

    See if you can join NCT07054723 on ClinicalTrials.gov

23. Collecting Tissue Samples for Future Research From Women Undergoing Surgery for Breast Cancer

    RATIONALE: Collecting and storing samples of tumor tissue from patients with breast cancer to study in the laboratory may help doctors learn more about cancer. PURPOSE: This phase I study is collecting tissue samples for future research from women undergoing surgery for breast cancer.

    Stage

    Not phased

    Ages

    Any age

    Site

    Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT00898131 on ClinicalTrials.gov

24. Strength After Breast Cancer

    The goal of this study is to explore whether a group exercise program called Strength After Breast Cancer can be delivered in an outpatient physical therapy clinic to improve physical function among women after treatment for breast cancer. The main questions this study aims to answer are: * Can the…

    Stage

    Not phased

    Ages

    18 and older

    Site

    MGH Institute of Health Professions, Boston, Massachusetts

    Run by

    MGH Institute of Health Professions

    See if you can join NCT06052488 on ClinicalTrials.gov

25. UNC Pleural Fluid Registry

    Research with biospecimens such as blood, tissue, or body fluids can help researchers understand how the human body works. Researchers can make new tests to find diseases, understand how treatments work, or find new ways to treat a disease. The purpose of this study is to collect biospecimens for r…

    Stage

    Not phased

    Ages

    18 and older

    Site

    UNC Lingeberger Comprehensive Cancer Center, Chapel Hill, North Carolina

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT05620329 on ClinicalTrials.gov