Breast Cancer Clinical Trials

415 studies are recruiting for breast cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 16

1. Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations

   The purpose of this study is to learn more about the effects of your BRCA mutation on the ovaries. The BRCA gene can make it hard to conceive a child in the future. It may also bring on early menopause. The researchers will check blood levels of hormones that the ovaries produce. The hormones that …

   Stage

   Not phased

   Ages

   18 to 44

   Site

   Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey

   Locations

   8 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT00823654 on ClinicalTrials.gov

2. Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria (Mobile Health: Technology and Outcomes in Low and Middle-Income Countries)

   The purpose of this study is to train Nigerian radiologists to perform ultrasound-guided breast biopsies. Researchers will use mHealth devices to create a sustainable and practical way of training radiologists in Nigeria to perform and clinically implement US-guided breast biopsies into their pract…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York

   Locations

   8 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT05561842 on ClinicalTrials.gov

3. Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

   This is an exploratory phase II interventional study that initiates standard-of-care anti-estrogen treatment preoperatively for 4-12 weeks (+/- 2 weeks).

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin

   Run by

   Medical College of Wisconsin

   See if you can join NCT06361940 on ClinicalTrials.gov

4. The COMPASSION Study

   The aim of this research study is to better understand the in-home hospice experience for participants, caregivers, hospice nurses, and oncology providers by conducting telehealth check-ins between participants and caregivers and oncology care teams.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Dana-Farber Cancer Institute, Boston, Massachusetts

   Run by

   Dana-Farber Cancer Institute

   See if you can join NCT06507930 on ClinicalTrials.gov

5. UCF MammoChat: Image Repository

   This study aims to develop AI models to better read diagnostic mammograms for various populations and types of breast cancer, using the images that participants donate and their responses from study questionnaire to improve patient outcomes. This study also aims to provide mammography images to par…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Central Florida, Orlando, Florida

   Run by

   University of Central Florida

   See if you can join NCT07214883 on ClinicalTrials.gov

6. Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer

   Breast cancer (BC) is the most frequently diagnosed cancer in women. Systemic cancer treatments are an important contributor to dramatic improvements in the long-term survival of women with BC. However, cancer treatment can lead to cognitive impairment and declines in quality of life in women with …

   Stage

   Not phased

   Ages

   45 to 75

   Site

   Ohio State University Comprehensive Cancer Center, Columbus, Ohio

   Run by

   Ohio State University Comprehensive Cancer Center

   See if you can join NCT05984888 on ClinicalTrials.gov

7. Community-led Navigation to Address Disparities in Mammography Among Native American Women

   The goal of this study is to evaluate the effectiveness of an intervention to promote breast cancer screening mammography among women in one community on the Navajo Nation. The intervention is Tablet-based Education to improve the Acceptance of Mammography (TEAM). TEAM encompasses culturally-tailor…

   Stage

   Not phased

   Ages

   40 to 74

   Site

   Navajo Nation Center for Indigenous Health, Chinle, Arizona

   Run by

   Johns Hopkins Bloomberg School of Public Health

   See if you can join NCT06957535 on ClinicalTrials.gov

8. Guided Meditation During Radiation Therapy for Breast and Gynecological Malignancies

   The goal of this study is to assess the effect of brief mindfulness-guided meditations during radiation therapy (RT) for patients with anxiety related to RT for breast and gynecological cancers.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Huntsman Cancer Institute at University of Utah, Salt Lake City, Utah

   Run by

   University of Utah

   See if you can join NCT07166042 on ClinicalTrials.gov

9. All-extremity Exercise During Breast Cancer Chemotherapy

   Currently, there are 3.5 million breast cancer survivors in the United States and this number is expected to increase dramatically. The proposed research will examine whether a novel exercise intervention for breast cancer patients who are undergoing chemotherapy protects against cardiovascular dys…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Integrative Cardiovasculal Physiology Laboratory, University of Florida, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT04914663 on ClinicalTrials.gov

10. Intra-Operative Radiation Registry

    This registry trial is designed to track the local control rates and side effects of IORT, which will be implemented for women who are suitable partial breast irradiation (PBI) per the latest American Society of Radiation Oncology (ASTRO) guidelines.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Montefiore Medical Center - Moses Campus, The Bronx, New York

    Run by

    Albert Einstein College of Medicine

    See if you can join NCT04994067 on ClinicalTrials.gov

11. Individuals on Hormone Therapy Breast Cancer Screening Pilot

    This investigation is a prospective breast cancer screening study open to all individuals on hormone therapy. Using a mixed methods approach, the study will 1) gather prospective quantitative breast imaging data in conjunction with hormone therapy and family cancer history and 2) investigate indivi…

    Stage

    Not phased

    Ages

    30 to 75

    Site

    Medical College of Wisconsin, Milwaukee, Wisconsin

    Run by

    Medical College of Wisconsin

    See if you can join NCT06383026 on ClinicalTrials.gov

12. First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

    This is an open-label, FIH study designed to evaluate the maximum tolerated dose, recommended Phase 2 dose, safety, tolerability, PK, pharmacodynamics, and preliminary antineoplastic activity of RLY-2608, in advanced solid tumor patients with a Phosphatidylinositol-4,5-bisphosphate-3 kinase, cataly…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    The University of Arizona Cancer Center, Tucson, Arizona

    Locations

    37 in total

    Run by

    Relay Therapeutics, Inc.

    See if you can join NCT05216432 on ClinicalTrials.gov

13. TRUDI: TDXD+Durva in HER2+/Low IBC

    The purpose of this study is to test the safety and effectiveness of an investigational drug combination (trastuzumab deruxtecan and durvalumab) to learn whether the intervention works in treating Human Epidermal growth factor Receptor-2 (HER2)-expressing inflammatory breast cancer. The names of th…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Locations

    3 in total

    Run by

    Filipa Lynce, MD

    See if you can join NCT05795101 on ClinicalTrials.gov

14. Precise Oncology Interventions in Nutrition and Training (OnPoint)

    The purpose of this study is to see if survivors of breast, prostate, or colorectal cancer who receive a personal referral to a targeted nutrition and exercise program will be able to eat a healthier diet and be more physically activity.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Miami, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT06534918 on ClinicalTrials.gov

15. Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer

    The purpose of this study is to determine if the dose of radiation therapy that is effective in producing a treatment response, delivered over a shorter treatment period, is a safe approach that causes few or mild side effects in women with newly diagnosed breast cancer or DCIS who have had a lumpe…

    Stage

    Phase 2

    Ages

    45 and older

    Site

    Norwalk Hospital, Norwalk, Connecticut

    Locations

    9 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT04084730 on ClinicalTrials.gov

16. Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

    The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will prove to be beneficial for women with early stage breast cancer. A clinical study is necessary to co…

    Stage

    Phase 2

    Ages

    50 and older

    Site

    Mayo Clinic, Scottsdale, Arizona

    Locations

    9 in total

    Run by

    Proton Collaborative Group

    See if you can join NCT01766297 on ClinicalTrials.gov

17. High-Resolution Lower Dose Dedicated Breast Computed Tomography (CT)

    This study is being performed to find out if a new kind of breast imaging (called dedicated breast CT or BCT) can help doctors to see the small structures in breast tissue more clearly. The investigators also want to find out if using the BCT will provide a more accurate diagnosis of breast cancer.

    Stage

    Not phased

    Ages

    40 and older

    Site

    University of Arizona, Tucson, Arizona

    Run by

    University of Arizona

    See if you can join NCT03954431 on ClinicalTrials.gov

18. MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

    The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enabl…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Providence Alaska Medical Center, Anchorage, Alaska

    Locations

    134 in total

    Run by

    Agendia

    See if you can join NCT03053193 on ClinicalTrials.gov

19. Community Services Navigation to Advance Health Equity in Breast Cancer Screening

    The goal of this study is to evaluate if adding community services navigation to the standard referral process for social needs is an effective and scalable strategy for addressing disparities in follow-up to abnormal breast cancer screening results. The investigators will determine the effectivene…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Utah Health Hospitals/Huntsman Cancer Institute Population Sciences, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT06305312 on ClinicalTrials.gov

20. Role of the Immune Environment in Response to Therapy in Breast Cancer

    This is an observational case-control study of tissues collected from women with ER+HER2- breast cancers. The immune environments of these cancers will be compared to triple negative and HER2+ breast cancers. No randomization or changes to standard of care treatment will occur as part of the study.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Abramson Cancer Center, Philadelphia, Pennsylvania

    Run by

    Abramson Cancer Center at Penn Medicine

    See if you can join NCT05396612 on ClinicalTrials.gov

21. A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

    This is an adaptive Phase 2, open-label, randomized, multi-center study evaluating up to 2 regimens of PCS6422 with capecitabine (Cap) vs. standard dose of Cap alone in patients with advanced or metastatic breast cancer. The goal of the study is to assess the efficacy and safety of PCS6422 + Cap as…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Arizona Oncology Associates, Tucson, Arizona

    Locations

    13 in total

    Run by

    Processa Pharmaceuticals

    See if you can join NCT06568692 on ClinicalTrials.gov

22. Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer

    The purpose of this study is to test BTX-9341 alone or in combination with fulvestrant (a currently marketed medication for breast cancer) in participants with advanced and/or metastatic hormone receptor positive (HR+)/human epidermal growth factor receptor 2 negative (HER2-) breast cancer. The stu…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Biotheryx Investigative Site, Rochester, Minnesota

    Locations

    6 in total

    Run by

    Biotheryx, Inc.

    See if you can join NCT06515470 on ClinicalTrials.gov

23. Breast Elasticity Imaging During Neoadjuvant Chemotherapy

    For this study, the investigators propose investigation of a new imaging technique, Harmonic Motion Imaging (HMI), and the evaluation of its potential role in prediction of breast cancer response to neoadjuvant chemotherapy (NACT). The investigators hypothesize that changes in HMI parameters will p…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Columbia University Irving Medical Center/NYP, New York, New York

    Run by

    Columbia University

    See if you can join NCT04824027 on ClinicalTrials.gov

24. A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

    ATLAS-101 is a Phase I/II clinical trial of AMXI-5001 in adult participants with advanced malignancies who have previously failed other therapies. The study has two phases. The purpose of Phase I (Dose Escalation) is to confirm the appropriate treatment dose and Phase II (Dose Expansion) is to char…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    University of California, Los Angles (UCLA) Department of Medicine - Hematology/Oncology, Los Angeles, California

    Locations

    4 in total

    Run by

    AtlasMedx, Incorporated

    See if you can join NCT04503265 on ClinicalTrials.gov

25. Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer

    The goal of this study is to evaluate the safety and effectiveness of adjuvant chemoradiation therapy in high-risk breast cancer patients who had received neoadjuvant chemotherapy before their lumpectomy and/or mastectomy and were found to have residual disease. As well as examine the effects of th…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Virginia, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT05288777 on ClinicalTrials.gov