Breast Cancer Clinical Trials

414 studies are recruiting for breast cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 16

1. WashU DIEP Flap Video and Patient Understanding Improvement

   Patients will complete a survey before and after watching the WashU DIEP Flap Video at their pre-operative standard of care visit, and a third survey at their post-operative standard of care visit. These surveys will use questions from SILS, APAIS, PEMAT, and AIM/IAM to assess the patient's health …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Washington University School of Medicine, St Louis, Missouri

   Run by

   Washington University School of Medicine

   See if you can join NCT06864754 on ClinicalTrials.gov

2. ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy

   The purpose of this study is to compare any good and bad effects of giving radiation treatment for breast cancer in 3 treatments over about 2 days.

   Stage

   Phase 2

   Ages

   45 to 79

   Site

   Virginia Commonwealth University, Richmond, Virginia

   Run by

   Virginia Commonwealth University

   See if you can join NCT06185205 on ClinicalTrials.gov

3. Enhancing Mammography Programs for Outreach, Wellness, Education, and Resources (EMPOWER) in Underserved Populations Study

   This study is investigating the feasibility of a digital tool called a chatbot for providing educational information about mammography through a tablet, computer, or phone. This study will recruit participants who recently had a mammogram with the University of Utah. Based on their mammography resu…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Huntsman Cancer Institute/ University of Utah, Salt Lake City, Utah

   Run by

   University of Utah

   See if you can join NCT07029490 on ClinicalTrials.gov

4. Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots

   To evaluate a community-based outreach initiative for screening, diagnosis, and treatment of breast, lung, and prostate cancers in underserved adults using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) implementation science framework.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Adventhealth, Orlando, Florida

   Run by

   AdventHealth

   See if you can join NCT07231159 on ClinicalTrials.gov

5. RADIANT: Pre-op Radiation With Abemaciclib and Letrozole

   This phase 1b study investigates the safety and feasibility of combining pre-operative radiation therapy with Cyclin-Dependent Kinase 4 (CDK4/6) inhibitors in participants with hormone receptor positive/HER2 negative (HR+/HER2-) breast cancer. The study aims to assess the benefits of concurrent use…

   Stage

   Phase 1

   Ages

   60 and older

   Site

   RWJBarnabas Health Clara Maas Medical Center, Belleville, New Jersey

   Locations

   4 in total

   Run by

   Mridula George, MD

   See if you can join NCT06139107 on ClinicalTrials.gov

6. Breast Re-irradiation After Second Ipsilateral Lumpectomy

   The purpose of this research study is to test the safety and possible harms of treating breast cancer with reirradiation, after breast surgery. The researchers want to find out what effects (good and bad) reirradiation has on people who have already received radiation before surgery.

   Stage

   Not phased

   Ages

   40 and older

   Site

   Lynn Cancer Institute at Baptist Health, Inc., Boca Raton, Florida

   Locations

   2 in total

   Run by

   Youssef Zeidan

   See if you can join NCT06867484 on ClinicalTrials.gov

7. TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer

   The aim of this study is to assess feasibility of a new imaging technology in the management of breast cancer - Tumor Microenvironment of Metastasis - Magnetic Resonance imaging (TMEM-MRI).

   Stage

   Not phased

   Ages

   18 and older

   Site

   Montefiore Medical Center, The Bronx, New York

   Run by

   Montefiore Medical Center

   See if you can join NCT03694756 on ClinicalTrials.gov

8. A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

   The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer.

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey

   Locations

   7 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT06144164 on ClinicalTrials.gov

9. Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks

   The purpose this research is to compare two different standards of care for pain management and two different standards of care for local numbing medicine for breast cancer patients who will have a total mastectomy.

   Stage

   Phase 4

   Ages

   18 and older

   Site

   University of Cincinnati Medical Center, Cincinnati, Ohio

   Run by

   University of Cincinnati

   See if you can join NCT06574022 on ClinicalTrials.gov

10. Lifting More Than Weights: Resistance Exercise Program Across Socioeconomic Groups for Cancer-Related Fatigue Management

    The long-term goal of this project is to improve the implementation of tailored resistance exercise interventions for Appalachian breast cancer survivors. To achieve this goal, the primary objective is to enhance the understanding of how biological, psychological, and social factors interact to inf…

    Stage

    Not phased

    Ages

    18 and older

    Site

    West Virginia University, Morgantown, West Virginia

    Run by

    West Virginia University

    See if you can join NCT06960720 on ClinicalTrials.gov

11. High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer

    The overall goal of this project is to develop an integrative system of breast cancer risk assessment based on epidemiologic and biologic risk variables, as well as to develop or refine risk biomarkers which may be useful in predicting and monitoring response to prevention interventions.

    Stage

    Not phased

    Ages

    30 to 65

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    Carol Fabian, MD

    See if you can join NCT00291096 on ClinicalTrials.gov

12. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical…

    Stage

    Not phased

    Ages

    Any age

    Site

    Massive Bio SYNERGY-AI site, Birmingham, Alabama

    Locations

    68 in total

    Run by

    Massive Bio, Inc.

    See if you can join NCT03452774 on ClinicalTrials.gov

13. Collecting Tissue Samples for Future Research From Women Undergoing Surgery for Breast Cancer

    RATIONALE: Collecting and storing samples of tumor tissue from patients with breast cancer to study in the laboratory may help doctors learn more about cancer. PURPOSE: This phase I study is collecting tissue samples for future research from women undergoing surgery for breast cancer.

    Stage

    Not phased

    Ages

    Any age

    Site

    Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT00898131 on ClinicalTrials.gov

14. Strength After Breast Cancer

    The goal of this study is to explore whether a group exercise program called Strength After Breast Cancer can be delivered in an outpatient physical therapy clinic to improve physical function among women after treatment for breast cancer. The main questions this study aims to answer are: * Can the…

    Stage

    Not phased

    Ages

    18 and older

    Site

    MGH Institute of Health Professions, Boston, Massachusetts

    Run by

    MGH Institute of Health Professions

    See if you can join NCT06052488 on ClinicalTrials.gov

15. The COMPASSION Study

    The aim of this research study is to better understand the in-home hospice experience for participants, caregivers, hospice nurses, and oncology providers by conducting telehealth check-ins between participants and caregivers and oncology care teams.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dana-Farber Cancer Institute, Boston, Massachusetts

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT06507930 on ClinicalTrials.gov

16. UCF MammoChat: Image Repository

    This study aims to develop AI models to better read diagnostic mammograms for various populations and types of breast cancer, using the images that participants donate and their responses from study questionnaire to improve patient outcomes. This study also aims to provide mammography images to par…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Central Florida, Orlando, Florida

    Run by

    University of Central Florida

    See if you can join NCT07214883 on ClinicalTrials.gov

17. Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer

    Breast cancer (BC) is the most frequently diagnosed cancer in women. Systemic cancer treatments are an important contributor to dramatic improvements in the long-term survival of women with BC. However, cancer treatment can lead to cognitive impairment and declines in quality of life in women with …

    Stage

    Not phased

    Ages

    45 to 75

    Site

    Ohio State University Comprehensive Cancer Center, Columbus, Ohio

    Run by

    Ohio State University Comprehensive Cancer Center

    See if you can join NCT05984888 on ClinicalTrials.gov

18. Guided Meditation During Radiation Therapy for Breast and Gynecological Malignancies

    The goal of this study is to assess the effect of brief mindfulness-guided meditations during radiation therapy (RT) for patients with anxiety related to RT for breast and gynecological cancers.

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Huntsman Cancer Institute at University of Utah, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT07166042 on ClinicalTrials.gov

19. All-extremity Exercise During Breast Cancer Chemotherapy

    Currently, there are 3.5 million breast cancer survivors in the United States and this number is expected to increase dramatically. The proposed research will examine whether a novel exercise intervention for breast cancer patients who are undergoing chemotherapy protects against cardiovascular dys…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    Integrative Cardiovasculal Physiology Laboratory, University of Florida, Gainesville, Florida

    Run by

    University of Florida

    See if you can join NCT04914663 on ClinicalTrials.gov

20. First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

    This is an open-label, FIH study designed to evaluate the maximum tolerated dose, recommended Phase 2 dose, safety, tolerability, PK, pharmacodynamics, and preliminary antineoplastic activity of RLY-2608, in advanced solid tumor patients with a Phosphatidylinositol-4,5-bisphosphate-3 kinase, cataly…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    The University of Arizona Cancer Center, Tucson, Arizona

    Locations

    37 in total

    Run by

    Relay Therapeutics, Inc.

    See if you can join NCT05216432 on ClinicalTrials.gov

21. High-Resolution Lower Dose Dedicated Breast Computed Tomography (CT)

    This study is being performed to find out if a new kind of breast imaging (called dedicated breast CT or BCT) can help doctors to see the small structures in breast tissue more clearly. The investigators also want to find out if using the BCT will provide a more accurate diagnosis of breast cancer.

    Stage

    Not phased

    Ages

    40 and older

    Site

    University of Arizona, Tucson, Arizona

    Run by

    University of Arizona

    See if you can join NCT03954431 on ClinicalTrials.gov

22. MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

    The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enabl…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Providence Alaska Medical Center, Anchorage, Alaska

    Locations

    134 in total

    Run by

    Agendia

    See if you can join NCT03053193 on ClinicalTrials.gov

23. Community Services Navigation to Advance Health Equity in Breast Cancer Screening

    The goal of this study is to evaluate if adding community services navigation to the standard referral process for social needs is an effective and scalable strategy for addressing disparities in follow-up to abnormal breast cancer screening results. The investigators will determine the effectivene…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Utah Health Hospitals/Huntsman Cancer Institute Population Sciences, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT06305312 on ClinicalTrials.gov

24. Role of the Immune Environment in Response to Therapy in Breast Cancer

    This is an observational case-control study of tissues collected from women with ER+HER2- breast cancers. The immune environments of these cancers will be compared to triple negative and HER2+ breast cancers. No randomization or changes to standard of care treatment will occur as part of the study.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Abramson Cancer Center, Philadelphia, Pennsylvania

    Run by

    Abramson Cancer Center at Penn Medicine

    See if you can join NCT05396612 on ClinicalTrials.gov

25. Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer

    The purpose of this study is to test BTX-9341 alone or in combination with fulvestrant (a currently marketed medication for breast cancer) in participants with advanced and/or metastatic hormone receptor positive (HR+)/human epidermal growth factor receptor 2 negative (HER2-) breast cancer. The stu…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Biotheryx Investigative Site, Rochester, Minnesota

    Locations

    6 in total

    Run by

    Biotheryx, Inc.

    See if you can join NCT06515470 on ClinicalTrials.gov