Breast Cancer Clinical Trials

415 studies are recruiting for breast cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

By city

Studies, page 13

1. NearWave Optical Molecular Monitoring

   The purpose of this study is to assess the feasibility of the NearWave optical molecular monitoring system for monitoring therapy progression and predicting pathologic complete response (pCR) of breast cancer patients undergoing neoadjuvant chemotherapy (NAC).

   Stage

   Not phased

   Ages

   18 and older

   Site

   Indiana University Simon Comprehensive Cancer Center, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT06744465 on ClinicalTrials.gov

2. Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

   This is a multicenter, open-label FIH, Phase 1a (dose escalation), Phase 1b (dose expansion) and Phase 2 study in patients with advanced metastatic solid tumors refractory to standard treatment.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California

   Locations

   7 in total

   Run by

   MBrace Therapeutics

   See if you can join NCT07145255 on ClinicalTrials.gov

3. A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

   Phase 1 dose escalation and expansion study of CLSP-1025, a first-in-class HLA-A*02:01 specific T cell engager (TCE) targeting solid tumors that harbor the p53 R175H mutation.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   HonorHealth Research Institute, Scottsdale, Arizona

   Locations

   21 in total

   Run by

   Clasp Therapeutics, Inc.

   See if you can join NCT06778863 on ClinicalTrials.gov

4. Bortezomib Followed by Pembrolizumab and Cisplatin in metTNBC

   The hypothesis of this pilot trial is that administration of bortezomib will inhibit NHEJ in metastatic TNBC leading at the time of disease progression to metastases that are HR-deficient and sensitive to pembrolizumab and cisplatin therapy. The trial will include in depth analysis of the patients'…

   Stage

   EARLY_Phase 1

   Ages

   18 and older

   Site

   Baylor University Medical Center, Baylor Charles A Sammons Cancer Center, Dallas, Texas

   Run by

   Baylor Research Institute

   See if you can join NCT04265872 on ClinicalTrials.gov

5. Tirzepatide Weight Loss for MRD+ Early Breast Cancer

   This trial aims to asses if tirzepatide-induced weight loss will lead to metabolic and hormonal changes in hormone receptor-positive (HR+), human epidermal growth factor receptor-negative (HER2-), node-positive (N+) high risk early breast cancer patients with obesity or overweight, inhibiting the g…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Baylor University Medical Center, Baylor Charles A Sammons Cancer Center, Dallas, Texas

   Run by

   Baylor Research Institute

   See if you can join NCT06517212 on ClinicalTrials.gov

6. Evaluating the Use of a Medication 'Switch' vs Guideline-directed Interventions for Relieving Side Effects of Aromatase Inhibitors Among Breast Cancer Patients

   Researchers have learned that about 50% of women do not finish the standard 5-year breast cancer treatment with an aromatase inhibitor. An aromatase inhibitor is hormone therapy that lowers the chance of breast cancer coming back (recurring) after surgery by blocking an enzyme in fat tissue called …

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Dartmouth Cancer Center, Lebanon, New Hampshire

   Run by

   Dartmouth-Hitchcock Medical Center

   See if you can join NCT07071038 on ClinicalTrials.gov

7. Feasibility Study for the SIRA-1000, SIRA® RFA Electrosurgical Device as an Adjunct to Breast Conserving Surgery

   This study aims to assess the safety and clinical accuracy of the SIRA-1000, SIRA® RFA Electrosurgical Device in ablating margins post-lumpectomy in patients undergoing breast conserving surgery for breast cancer. Radiofrequency ablation, or RFA, uses radio waves to create heat, that in turn, cause…

   Stage

   Not phased

   Ages

   50 and older

   Site

   University of Texas Medical Branch at Galveston, TX, Galveston, Texas

   Run by

   Innoblative Designs, Inc.

   See if you can join NCT07206121 on ClinicalTrials.gov

8. Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

   This study is a first in human Phase 1 study that involves patients with a type of cancer called HER2 (Human Epidermal Growth Factor Receptor 2) positive cancer. This study asks patients to volunteer to take part in a research study investigating the safety and efficacy of using special immune cell…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Baylor St. Luke's Medical Center, Houston, Texas

   Run by

   Baylor College of Medicine

   See if you can join NCT03740256 on ClinicalTrials.gov

9. A Study of Revaree Plus in People With Breast Cancer

   The purpose of this study is to find out whether Revaree Plus is effective at improving vaginal health for people who are having symptoms of vaginal dryness during breast cancer treatment.

   Stage

   Phase 4

   Ages

   18 and older

   Site

   Memorial Sloan Kettering Basking Ridge (Consent Only), Basking Ridge, New Jersey

   Locations

   7 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT07042581 on ClinicalTrials.gov

10. Improving Care for Rural Patients With Solid Tumors

    This study will assess if the CARES (Cancer Advocacy, Resources, Education and Support) intervention improves time to start of treatment after diagnosis and time to treatment completion for solid tumors (ex: lung, head, neck, thyroid, cervical, breast, bladder, colon, and rectal cancers) in rural p…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    University of Colorado Hospital, Aurora, Colorado

    Locations

    14 in total

    Run by

    University of Colorado, Denver

    See if you can join NCT04916990 on ClinicalTrials.gov

11. CTNNA1 Familial Expansion Study

    The goal of the CAFÉ Study is to determine the cancer risks associated with germline CTNNA1 loss-of-function variants.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    Abramson Cancer Center at Penn Medicine

    See if you can join NCT05126290 on ClinicalTrials.gov

12. Exercise to ReGain Stamina and Energy (The EXERGISE Study)

    About 20%-70% of breast cancer survivors experience fatigue after cancer therapy. Because epidemiologic evidence shows that old age is a risk factor for fatigue in adults with cancer history, older breast cancer survivors suffer from even more fatigue than younger survivors. The purpose of this stu…

    Stage

    Not phased

    Ages

    60 to 105

    Site

    Institute on Aging; University of Florida, Gainesville, Florida

    Run by

    University of Florida

    See if you can join NCT05684367 on ClinicalTrials.gov

13. Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors

    This study investigates the efficacy of a telehealth exercise program designed specifically for rural cancer survivors with cancer-related fatigue (CRF). Small dried blood samples and measures of physical function will be collected throughout the program. The main questions it aims to answer are: *…

    Stage

    Phase 2

    Ages

    18 to 89

    Site

    University of Colorado Anschutz Medical Campus, Aurora, Colorado

    Locations

    2 in total

    Run by

    University of Colorado, Denver

    See if you can join NCT07001241 on ClinicalTrials.gov

14. The MIND-BC Study: MIND Diet for Breast Cancer Cognition

    This fully, powered efficacy RCT, the MIND diet for Breast Cancer Cognition (MIND-BC), will evaluate the MIND diet in a rigorous, highly controlled academic cancer center. We will recruit breast cancer survivors reporting CRCI with a MIND diet score < 8, based on a previously devised 14-item diet q…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Moffitt Cancer Center, Tampa, Florida

    Run by

    H. Lee Moffitt Cancer Center and Research Institute

    See if you can join NCT07018986 on ClinicalTrials.gov

15. Nutrition Awareness Among Women With Non-Metastatic Breast Cancer

    This study explores perspectives of women with non-metastatic breast cancer regarding their willingness and ability to make dietary changes pertaining to foods/food products that may pose a risk to their cancer prognosis and survival. This is a single-group study conducted entirely online. All stud…

    Stage

    Not phased

    Ages

    18 and older

    Site

    UNC Cancer Hospital, Chapel Hill, North Carolina

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT07389967 on ClinicalTrials.gov

16. EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

    The purpose of this research study is to evaluate the outcomes of two standard of care group exercise regimens to increase muscle mass in women who have been treated with breast cancer.

    Stage

    Not phased

    Ages

    20 to 89

    Site

    Allegheny General Hospital, Pittsburgh, Pennsylvania

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT06115486 on ClinicalTrials.gov

17. Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

    This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 …

    Stage

    Not phased

    Ages

    20 to 89

    Site

    Allegheny General Hospital, Pittsburgh, Pennsylvania

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT07023887 on ClinicalTrials.gov

18. Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer

    In this study, the investigators hypothesize that a high dose of post-workout protein nutrition regimen focused on food quality and an observed exercise regimen utilizing high-load resistance training initiated during or after cancer treatment will improve body composition and functional capacity.

    Stage

    Not phased

    Ages

    20 to 89

    Site

    Allegheny General Hospital, Pittsburgh, Pennsylvania

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT06858449 on ClinicalTrials.gov

19. Efficacy of OneMark Device in Identifying Breast Cancer for Surgery and Surveillance

    The goal of this research is to study a localization device for breast cancer called OneMark. This device will be studied in breast cancer surgery and during surveillance in patients being monitored for breast cancer. The main questions the study aims to answer are: Can surgeons visualize the OneMa…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of California, San Diego, La Jolla, California

    Run by

    University of California, San Diego

    See if you can join NCT07087691 on ClinicalTrials.gov

20. Harnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCA

    The HARMONY trial is an interventional trial enrolling metastatic breast cancer (MBC). Current treatment of breast cancer uses clinical subtype information (e.g. hormone receptor-positive (HR+)) to help guide treatment options. Breast cancer can also be characterized by molecular subtype, but it is…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

    Locations

    2 in total

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT03769415 on ClinicalTrials.gov

21. The Immune System's Response to Young Women's Breast Cancer

    This study plans to learn more about the immune system's response to breast cancer in young women.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Colorado Denver, Aurora, Colorado

    Locations

    5 in total

    Run by

    University of Colorado, Denver

    See if you can join NCT01503190 on ClinicalTrials.gov

22. Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

    The objective of this study is to evaluate the safety, tolerability, and efficacy of BL-B01D1 in patients with Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Beverly Hills Cancer Center, Beverly Hills, California

    Locations

    39 in total

    Run by

    SystImmune Inc.

    See if you can join NCT05983432 on ClinicalTrials.gov

23. Converting HR+ Breast Cancer Into an Individualized Vaccine

    Newly diagnosed post-menopausal women with clinical stage II-III, HR+HER2- breast cancer are eligible to a randomized trial, concurrently open at five US academic institutions. Patients receiving 4 months of standard neoadjuvant hormonal therapy with letrozole are randomly assigned to one of 4 arms…

    Stage

    Phase 2

    Ages

    18 to 90

    Site

    New York Presbyterian Hospital - Queens, New York, New York

    Locations

    8 in total

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT03804944 on ClinicalTrials.gov

24. Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

    The purpose of this study is to determine the effectiveness of a digital health program called AYA STEPS, which is designed to help adolescent and young adult (AYA) cancer survivors manage symptoms and engage in recommended follow-up care.

    Stage

    Not phased

    Ages

    18 to 39

    Site

    Duke Cancer Institute, Durham, North Carolina

    Run by

    Duke University

    See if you can join NCT06371768 on ClinicalTrials.gov

25. Personalized Second Chance Breast Conservation (PSCBC): A Prospective Phase II Clinical Study

    The goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with in-breast recurrences after a previous lumpectomy and RT, investigators propose to test partial breast irradiation with the target volume encompassing the entire surgical bed…

    Stage

    Not phased

    Ages

    19 to 90

    Site

    New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York

    Locations

    3 in total

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT04371913 on ClinicalTrials.gov