Sepsis Clinical Trials

36 studies are recruiting for sepsis in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Role of Transposable Elements in Septic Immune Aging

   The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is: 1. Do transposable elements prematurely age the immune systems of patients with sepsis? 2. Do transposable elements correlate with i…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT06809868 on ClinicalTrials.gov

2. PIVO Use for Blood Cultures in the Emergency Department

   The investigators will implement a protocol for use of the PIVO device for blood culture collection in the emergency department. This protocol utilizes the device in various scenarios to reduce needlesticks while allowing for accurate and appropriate assessment of potential pathogens in the bloodst…

   Stage

   Not phased

   Ages

   Any age

   Site

   Park City Hospital, Park City, Utah

   Run by

   Intermountain Health Care, Inc.

   See if you can join NCT07348289 on ClinicalTrials.gov

3. Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis

   In this research study we want to learn more about the character of neutrophils that are present in the blood of children with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's immune system. Eve…

   Stage

   Not phased

   Ages

   0 to 17

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT04103268 on ClinicalTrials.gov

4. Pathological Myeloid Activation After Sepsis and Trauma

   The goal of this observational study is to better understand what happens to circulating blood after a patient experiences severe trauma injury. The main questions it aims to answer are: Is severe human trauma associated with specific patterns of development in the hematopoietic stem cells of these…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   UF Health at Shands Hospital, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT05616130 on ClinicalTrials.gov

5. Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis

   The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU). There are two groups of subjects in this study: PICU clinicians/sepsi…

   Stage

   Not phased

   Ages

   Any age

   Site

   Children's Healthcare of Atlanta, Atlanta, Georgia

   Locations

   4 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT05975671 on ClinicalTrials.gov

6. The RightCall: Implementing a Sepsis Diagnostic Toolkit to Improve Pediatric Diagnosis in ED Transfer Calls

   Sepsis is a leading cause of death in children, and an early diagnosis that improves outcomes is less likely in children who are treated in general Emergency Departments (EDs), that treat adults and children, compared to pediatric Emergency Departments. The study team, in collaboration with investe…

   Stage

   Not phased

   Ages

   0 and older

   Site

   Children's Hospital Colorado, Aurora, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT07051668 on ClinicalTrials.gov

7. Change in MAPSE During Treatment of Sepsis

   Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the fo…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Maryland Medical Center, Baltimore, Maryland

   Run by

   University of Maryland, Baltimore

   See if you can join NCT05634733 on ClinicalTrials.gov

8. Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates

   The CLEAN (ChLorine to reduce Enteric and Antibiotic resistant infections in Neonates) cluster randomized controlled trial in western Kenya will evaluate the impact of a multi-component chlorination intervention in health care facilities on maternal and neonatal health. Intervention facilities will…

   Stage

   Not phased

   Ages

   Any age

   Site

   Kenya Medical Research Institute, Nairobi,

   Locations

   2 in total

   Run by

   University of California, Berkeley

   See if you can join NCT06824350 on ClinicalTrials.gov

9. A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02)

   This study is being conducted to evaluate the safety and effectiveness of VBI-S in elevating the blood pressure of septic shock patients with absolute or relative hypovolemia.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Dignity Health Chandler Regional Medical Center, Chandler, Arizona

   Locations

   6 in total

   Run by

   Vivacelle Bio

   See if you can join NCT06072430 on ClinicalTrials.gov

10. TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections

    A pre/post interventional use trial, with ED patients who are initially triaged to locations other than a dedicated patient room in the main ED (e.g., waiting room, hallway bed, and/or the staging area/fast track area) with suspected infection and tachycardia or fever will be enrolled. Study conduc…

    Stage

    Not phased

    Ages

    18 and older

    Site

    OSF HealthCare Saint Francis Medical Center, Peoria, Illinois

    Locations

    2 in total

    Run by

    Inflammatix

    See if you can join NCT06637904 on ClinicalTrials.gov

11. Prediction of Rehospitalization Following a Sepsis Admission Using a Wearable Biopatch

    The goal of this observational study is to learn about the utility of biopatches predicting 30-day readmissions in patients discharged from the hospital with sepsis. The main question[s] it aims to answer are: • Does the application of a biopatch provide data that can improve prediction of an unpla…

    Stage

    Not phased

    Ages

    18 and older

    Site

    UC San Diego Health, San Diego, California

    Run by

    University of California, San Diego

    See if you can join NCT05806762 on ClinicalTrials.gov