Sepsis Clinical Trials in Philadelphia, Pennsylvania

6 studies are recruiting for sepsis in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

   This study will enroll adults aged 18 to 80 years diagnosed with sepsis due to a suspected or confirmed bacterial infection, within 7 days of being admitted to the hospital, and who have also developed acute kidney injury within 72 hours of the onset of sepsis. Eligible participants will be randoml…

   Stage

   Phase 2

   Ages

   18 to 80

   Site

   Research Site, Philadelphia, Pennsylvania

   Locations

   74 in total

   Run by

   AstraZeneca

   See if you can join NCT07215702 on ClinicalTrials.gov

2. Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention

   The goal of this clinical trial is to determine if vancomycin dosing in children with sepsis can be improved by using updated, personalized dosing models that account for new markers of an individual's kidney function. Vancomycin is prescribed based on the known information of how the body breaks t…

   Stage

   Phase 1

   Ages

   0 to 17

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT07084129 on ClinicalTrials.gov

3. Safe and Explainable AI

   While current AI technology is suitable for automating some repetitive clinical tasks, technical challenges remain in solving critical and gainful problems in the domains of patient and disease management. The proposed research seeks to address issues in medical AI, such as integrating medical know…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   Abramson Cancer Center at Penn Medicine

   See if you can join NCT06694181 on ClinicalTrials.gov

4. The APS Phenotyping Study

   The goal of the observational APS phenotyping study is to better understand risk factors, potential biomarkers, length and severity of illness, and recovery for adults with ARDS, pneumonia, and/ or sepsis. This study will also generate a biobank of specimens collected from these patients that will …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   20 in total

   Run by

   Vanderbilt University Medical Center

   See if you can join NCT06521502 on ClinicalTrials.gov

5. External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients

   To demonstrate that external drainage of thoracic duct lymph during sepsis results in a reduction in circulating pro-inflammatory cytokines. To demonstrate safety and feasibility of early thoracic duct cannulation and external lymph drainage for up to 7 days in adult surgical intensive care patient…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT04855786 on ClinicalTrials.gov

6. Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis

   The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU). There are two groups of subjects in this study: PICU clinicians/sepsi…

   Stage

   Not phased

   Ages

   Any age

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   4 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT05975671 on ClinicalTrials.gov