Prostate Cancer Clinical Trials

289 studies are recruiting for prostate cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 12

1. Prostate Assessment with Restriction Spectrum Imaging (RSI) MRI

   This single-center study will enroll 40 male participants to complete 2 diffusion magnetic resonance images within 30 days of each other.

   Stage

   Not phased

   Ages

   18 and older

   Site

   UCSD Moores Cancer Center, La Jolla, California

   Run by

   University of California, San Diego

   See if you can join NCT04992728 on ClinicalTrials.gov

2. Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Efficacy Testing

   This protocol describes pilot testing of an educational shared decision-making intervention to help men with localized prostate cancer make decisions with their health care providers about if and when to de-escalate surveillance testing. The project is important because for many patients their canc…

   Stage

   Not phased

   Ages

   65 and older

   Site

   M.D. Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT06785441 on ClinicalTrials.gov

3. PSMA-PET to Guide Prostatectomy

   In this study, 196 patients will be randomized 1:1 to either having only the standard of care MRI prior to surgery versus having the standard of care MRI and the PSMA PET scan. PET (and MRI) findings will be validated against whole mount pathology. Pre-surgical imaging findings will also be evaluat…

   Stage

   Phase 2

   Ages

   40 to 80

   Site

   Goodman Hall, Indiana Institute for Biomedical Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana

   Run by

   Five Eleven Pharma, Inc.

   See if you can join NCT05381103 on ClinicalTrials.gov

4. Customized TULSA-PRO Ablation Registry

   This patient registry will capture data from patients who have been or who are undergoing the transurethral ultrasound ablation (TULSA) procedure as part of their routine clinical care. The registry will shed light on real-world outcomes of safety and efficacy of the procedure and understand how a …

   Stage

   Not phased

   Ages

   18 and older

   Site

   RadNet's Liberty Pacific West Hills Facility, West Hills, California

   Locations

   5 in total

   Run by

   Profound Medical Inc.

   See if you can join NCT05001477 on ClinicalTrials.gov

5. ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer

   This is a multicenter, multinational trial to evaluate advanced MRI techniques for improved detection of clinically significant prostate cancer (csPCa). The study will enroll 500 participants at 5 clinical centers (100 participants per center). The current standard MRI technique for prostate cancer…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California San Diego, San Diego, California

   Locations

   5 in total

   Run by

   University of California, San Diego

   See if you can join NCT06579417 on ClinicalTrials.gov

6. FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer

   The goal of this clinical trial is to learn if the vaccine FK-PC101 works to delay or prevent the return of prostate cancer in men who have had surgery to remove their prostate cancer. It will also learn about the safety of FK-PC101. The main questions it aims to answer are: Does FK-PC101 delay or …

   Stage

   Phase 2

   Ages

   Any age

   Site

   Central Ohio Urology Group, Gahanna, Ohio

   Locations

   3 in total

   Run by

   Cellvax Therapeutics Inc

   See if you can join NCT06636682 on ClinicalTrials.gov

7. Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test

   Prostate cancer is the most frequently diagnosed cancer in men in the Unites States. Nearly 1 million prostate biopsy procedures are performed in the United States annually and elevated prostate-specific antigen (PSA) level is the primary reason for prostate biopsy in > 90% of cases. However, at th…

   Stage

   Phase 4

   Ages

   18 to 80

   Site

   University of Chicago Medical Center, Chicago, Illinois

   Locations

   3 in total

   Run by

   Albany Medical College

   See if you can join NCT05629494 on ClinicalTrials.gov

8. Prostate Cancer Genetic Risk Evaluation and Screening Study

   This study aims to define the natural history of men at high genetic risk for prostate cancer on the basis of specific germline genetic mutations, family history, or Black/African ancestry and evaluate the utility of prostate MRI as a screening tool. The hypothesis is that this targeted population …

   Stage

   Not phased

   Ages

   35 to 74

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT05129605 on ClinicalTrials.gov

9. Focal Therapy for Localized Prostate Cancer

   This prospective registry and longitudinal study that is designed to carefully measure details of prostate cancer patients' outcomes with focal therapy. The goal of which is to improve patient care.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Diego, La Jolla, California

   Run by

   University of California, San Diego

   See if you can join NCT06270043 on ClinicalTrials.gov

10. A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest

    This research study is a pilot clinical trial, which hypothesizes that the combination of electromagnetic tracking in conjunction with laparoscope imaging and ultrasound probe imaging will aid in reducing the complexity of both laparoscopic lymphadenectomy and/or organ removal in patients with a co…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT05899361 on ClinicalTrials.gov

11. TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer

    This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia. It will assess the tolerance and safety of target fusion ablation of prostate cancer tumors using Laser Induced Thermal Therapy (TFA-LITT) guided by fusi…

    Stage

    Not phased

    Ages

    50 to 80

    Site

    Urology Specialist Group, Hialeah, Florida

    Run by

    Urological Research Network, LLC

    See if you can join NCT05698576 on ClinicalTrials.gov

12. Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer

    Pembrolizumab will be administered at a dose of 200 mg will be administered as a 30 minute IV infusion every 3 weeks. Enzalutamide will be administered at dose of 160 mg orally every day. All patients will be required to have at least one high-risk criteria.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    VA Portland Healthcare System, Portland, Oregon

    Run by

    Mark Garzotto, MD

    See if you can join NCT03753243 on ClinicalTrials.gov

13. PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

    The standard of care imaging of prostate cancer metastases recommended by the National Comprehensive Cancer Network (NCCN), CT of the chest/abdomen/pelvis and bone scan, may be suboptimal. PyL is a novel PET tracer designed to detect prostate specific membrane antigen (PSMA) expressed on prostate c…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Hoag Memorial Hospital Presbyterian, Irvine, California

    Run by

    Hoag Memorial Hospital Presbyterian

    See if you can join NCT04700332 on ClinicalTrials.gov

14. Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery

    This is a prospective phase II study to assess the efficacy and toxicity of HSV-tk+ valacyclovir gene therapy in combination with androgen deprivation therapy, brachytherapy, external beam radiotherapy, and prostatectomy in previously untreated high-risk prostate cancer.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Houston Methodist Hospital, Houston, Texas

    Run by

    The Methodist Hospital Research Institute

    See if you can join NCT03541928 on ClinicalTrials.gov