Malignant Solid Neoplasm Clinical Trials

93 studies are recruiting for malignant solid neoplasm in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. Increasing Knowledge and Interest in Cancer Clinical Trials

   This trial investigates how well a video-based clinical trial education session works in increasing knowledge and interest in cancer clinical trials among individuals in the metropolitan Detroit region of the Karmanos Cancer Institute (KCI) catchment area. This educational activity may help researc…

   Stage

   Not phased

   Ages

   21 and older

   Site

   Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

   Run by

   Hayley Thompson

   See if you can join NCT06501040 on ClinicalTrials.gov

2. Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

   This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relationship between respiration, cardiovascular effects in the brain, mental health, and neurophysiological…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT06788886 on ClinicalTrials.gov

3. Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients

   This clinical trial tests how well cognitive behavioral cancer stress management (CBCSM) group sessions work to decrease psychological distress in cancer patients. CBCSM teaches patients how to recognize and reduce the impacts of cancer associated stress on the biological, psychological, and social…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT06015932 on ClinicalTrials.gov

4. Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

   This phase II trial compares the impact of subcutaneous (SC) nivolumab given in an in-home setting to an in-clinic setting on cancer care and quality of life. Currently, most drug-related cancer care is conducted in clinic type centers or hospitals which may isolate patients from family, friends an…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Mayo Clinic in Florida, Jacksonville, Florida

   Run by

   Mayo Clinic

   See if you can join NCT06265285 on ClinicalTrials.gov

5. Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial

   This clinical trial tests the impact of the The Ohio State University Connecting Underrepresented Populations to Clinical Trials (CUSP2CT) project on clinical trial referrals and enrollment in racial/ethnic minorities. Progress in cancer prevention, detection and treatment can only be made by ident…

   Stage

   Not phased

   Ages

   Any age

   Site

   Ohio State University Comprehensive Cancer Center, Columbus, Ohio

   Run by

   Ohio State University Comprehensive Cancer Center

   See if you can join NCT06314672 on ClinicalTrials.gov

6. Ex Vivo Expansion (ACT-X)

   The purpose of this study is to understand how the body's immune cells respond to a new type of vaccine (neoantigen vaccine) designed to help the immune system recognize and fight cancer. To do this, the study team will collect a research specimen from participants to study their immune cells' reac…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Florida, Jacksonville, Florida

   Run by

   Mayo Clinic

   See if you can join NCT07137312 on ClinicalTrials.gov

7. Intravital Microscopy in Human Solid Tumors

   This study will investigate the tumor-associated vasculature of patients with solid tumors. The investigators will use a technology known as intravital microscopy (IVM) in order to visualize in real-time the vessels associated with solid tumors. The IVM observations may determine if an individual p…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic Florida, Jacksonville, Florida

   Run by

   Mayo Clinic

   See if you can join NCT03823144 on ClinicalTrials.gov

8. The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors

   The study investigates how the COVID-19 pandemic has impacted the psychological, financial, physical, and social well-being of adolescent and young adult (AYA) cancer patients and survivors. AYA cancer survivors have inferior long-term survival compared to the general population, and the negative i…

   Stage

   Not phased

   Ages

   18 to 39

   Site

   M D Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT04551378 on ClinicalTrials.gov

9. Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

   This study collects blood and tissue samples for research of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS)-related cancers. Collecting blood and tissue samples and studying biomarkers in the laboratory may help doctors to learn how are biologic or genetic factors rela…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UC San Diego Moores Cancer Center, La Jolla, California

   Locations

   8 in total

   Run by

   AIDS Malignancy Consortium

   See if you can join NCT05663502 on ClinicalTrials.gov

10. Acceptance and Commitment Therapy and Compassion-Based Virtual Group Therapy to Improve Psychological Wellbeing in Patients With Cancer

    This clinical trial tests how well acceptance and commitment therapy and compassion based virtual group therapy works to improve psychological wellbeing, such as compassion, understanding, and flexibility, in patients with cancer. Receiving a cancer diagnosis, undergoing cancer treatment, and livin…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Arizona, Scottsdale, Arizona

    Run by

    Mayo Clinic

    See if you can join NCT06246955 on ClinicalTrials.gov

11. Transportation for Cancer Care Navigation Tool for Reducing Travel Barriers Among Patients With Solid Tumors Receiving Radiation Therapy

    This clinical trial evaluates whether the Transportation for Cancer Care Navigation Tool (TRACT) can reduce travel barriers among patients with solid tumors receiving radiation therapy. It is estimated that 20-30% patients with cancer experience travel-related barriers for cancer care. This is a pa…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Emory University Hospital Midtown, Atlanta, Georgia

    Locations

    4 in total

    Run by

    Emory University

    See if you can join NCT06541158 on ClinicalTrials.gov

12. Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy

    This clinicaI trial is being done to determine if acupressure is helpful to reduce anxiety related to chemotherapy, compared with "sham" (or placebo) acupressure in patients with cancer. Anxiety, experienced by many patients with cancer, can be related to chemotherapy and may contribute to other sy…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT06723041 on ClinicalTrials.gov

13. Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method

    This study formulates consensus agreement on clinical key elements related to prostate cancer care that are critical for standardization and global reported using a robust Delphi technique, completely remote and electronic. The goal of this survey study is to have a panel of specialty-specific expe…

    Stage

    Not phased

    Ages

    21 and older

    Site

    M D Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT05054413 on ClinicalTrials.gov

14. A Culturally Informed Patient Navigation Program (CFPN) to Reduce Delays Between Diagnosis and Treatment in American Indian and Alaska Native Cancer Patients Living in Rural California

    This clinical trial develops and tests whether a culturally informed patient navigation program, Community-Focused Patient Navigation (CFPN), works to reduce delays between diagnosis and treatment in American Indian and Alaska Native (AIAN) cancer patients living in rural California. AIAN communiti…

    Stage

    Not phased

    Ages

    Any age

    Site

    Toiyabe Indian Health Project, Bishop, California

    Locations

    2 in total

    Run by

    University of Southern California

    See if you can join NCT07332312 on ClinicalTrials.gov

15. L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance

    This clinical trial tests the feasibility, best dose, and effectiveness of L-theanine for supporting relaxation and mood among cancer patients in surveillance. L-theanine is a substance found in the leaves of green tea with potential to enhance mental health and well-being. It works by increasing c…

    Stage

    EARLY_Phase 1

    Ages

    18 and older

    Site

    City of Hope Medical Center, Duarte, California

    Locations

    4 in total

    Run by

    City of Hope Medical Center

    See if you can join NCT07220447 on ClinicalTrials.gov

16. Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery

    This clinical trial tests how well guided meditation, compared to silence, works to reduce pre-operative anxiety in patients undergoing cancer-directed surgery. Pre-operative anxiety affects patient experience and has been found to be a predictor of severe post-operative pain and chronic pain after…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Ohio State University Comprehensive Cancer Center, Columbus, Ohio

    Run by

    Ohio State University Comprehensive Cancer Center

    See if you can join NCT06949943 on ClinicalTrials.gov

17. Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

    This phase III trial compares the effect of 3 study approaches in preventing chemotherapy-induced peripheral neuropathy: 1) cryocompression, 2) continuous compression, and 3) low cyclic compression. Taxane chemotherapy drugs, such as paclitaxel or docetaxel, can cause a nerve disorder called periph…

    Stage

    Phase 3

    Ages

    18 and older

    Site

    University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

    Locations

    36 in total

    Run by

    SWOG Cancer Research Network

    See if you can join NCT05642611 on ClinicalTrials.gov

18. Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

    This study examines how certain risk factors (such as age, gender, other medical conditions, and the type of immunotherapy used to treat the cancer) affect whether a patient with a malignant solid tumor will develop mild or serious side effects from the immunotherapy medications. Immunotherapy is t…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Anchorage Associates in Radiation Medicine, Anchorage, Alaska

    Locations

    849 in total

    Run by

    SWOG Cancer Research Network

    See if you can join NCT04871542 on ClinicalTrials.gov

19. A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

    This phase III single arm trial determines whether taking prophylactic letermovir will reduce the likelihood of infection with cytomegalovirus (CMV) in children and adolescents after stem cell transplant compared to estimated rate of infection without prophylaxis. The treatments used to prepare for…

    Stage

    Phase 3

    Ages

    2 to 18

    Site

    Children's Hospital of Alabama, Birmingham, Alabama

    Locations

    29 in total

    Run by

    Children's Oncology Group

    See if you can join NCT05711667 on ClinicalTrials.gov

20. Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell Transplant

    This clinical trial studies how well an exercise program (Totally Excited About Moving, Mobility, and Exercise [TEAM Me]) affects the exercise and dietary habits of pediatric and adolescents and young adults with cancer undergoing a blood stem cell transplant. TEAM Me is an exercise program that re…

    Stage

    Not phased

    Ages

    6 to 29

    Site

    UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

    Locations

    2 in total

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT04678427 on ClinicalTrials.gov

21. Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers

    This clinical trial assesses whether resource identification for primary caregivers can affect financial stress, quality of life, depression, and the general belief in the ability to cope with daily life. Caregivers of patients receiving cytoreductive surgery and hyperthermic intraperitoneal chemot…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT06709404 on ClinicalTrials.gov

22. Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

    This clinical trial studies the side effects of stereotactic radiosurgery and how well it works with or without vertebroplasty, separation surgery, or immunotherapy in patients with cancer that is radiation resistant and has spread to the spine (spinal metastases). Spinal metastases are rapidly pro…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Ohio State University Comprehensive Cancer Center, Columbus, Ohio

    Run by

    Ohio State University Comprehensive Cancer Center

    See if you can join NCT05178472 on ClinicalTrials.gov

23. INTERogating Cancer for Etiology, Prevention and Therapy Navigation

    This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients with cancer. Cancer genetic testing is a series of tests that finds specific changes in cancer cells a…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Arizona, Scottsdale, Arizona

    Locations

    3 in total

    Run by

    Mayo Clinic

    See if you can join NCT06008392 on ClinicalTrials.gov

24. Communication Issues in Patient and Provider Discussions of Immunotherapy

    This trials studies communication issues in patient and provider discussions about immunotherapy. The goal of this study is to describe where patients have heard about immunotherapy, what the participants understand about it, how physicians and other healthcare workers describe immunotherapy, and h…

    Stage

    Not phased

    Ages

    Any age

    Site

    Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia

    Locations

    2 in total

    Run by

    Emory University

    See if you can join NCT05873608 on ClinicalTrials.gov

25. Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

    This phase I/II trial studies the side effects of interstitial photodynamic therapy following palliative radiotherapy and how well it works in treating patients with inoperable malignant central airway obstruction. Patients who have advanced stage cancer tumors in the lung can often have the breath…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Roswell Park Cancer Institute, Buffalo, New York

    Locations

    2 in total

    Run by

    Roswell Park Cancer Institute

    See if you can join NCT06306638 on ClinicalTrials.gov