Malignant Solid Neoplasm Clinical Trials in Springfield, Illinois

8 studies are recruiting for malignant solid neoplasm in Springfield, Illinois right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

   This phase II ComboMATCH treatment trial compares the effect of neratinib to the combination of neratinib and palbociclib in treating patients with HER2 positive solid tumors. Neratinib and palbociclib are in a class of medications called kinase inhibitors. They work by blocking the action of an ab…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Southern Illinois University School of Medicine, Springfield, Illinois

   Locations

   194 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT06126276 on ClinicalTrials.gov

2. Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects

   This study collects research data and samples from patients who experience immunotherapy side effects to store for use in future research studies. Studying research data and samples from patients who experience immunotherapy side effects may help researchers better understand how to predict, preven…

   Stage

   Not phased

   Ages

   Any age

   Site

   Southern Illinois University School of Medicine, Springfield, Illinois

   Locations

   625 in total

   Run by

   Alliance for Clinical Trials in Oncology

   See if you can join NCT04242095 on ClinicalTrials.gov

3. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

   This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in the laboratory may help researchers develop tests for the earl…

   Stage

   Not phased

   Ages

   40 to 75

   Site

   Southern Illinois University School of Medicine, Springfield, Illinois

   Locations

   745 in total

   Run by

   Alliance for Clinical Trials in Oncology

   See if you can join NCT05334069 on ClinicalTrials.gov

4. Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

   This phase III trial compares the effect of giving triptorelin vs no triptorelin in preventing ovarian damage in adolescents and young adults (AYAs) with cancer receiving chemotherapy with alkylating agents. Alkylating agents are part of standard chemotherapy, but may cause damage to the ovaries. I…

   Stage

   Phase 3

   Ages

   Up to 39

   Site

   Saint John's Hospital, Springfield, Illinois

   Locations

   206 in total

   Run by

   Children's Oncology Group

   See if you can join NCT06513962 on ClinicalTrials.gov

5. Project: Every Child for Younger Patients With Cancer

   This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

   Stage

   Not phased

   Ages

   Up to 25

   Site

   Saint John's Hospital, Springfield, Illinois

   Locations

   279 in total

   Run by

   Children's Oncology Group

   See if you can join NCT02402244 on ClinicalTrials.gov

6. Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

   This study examines how certain risk factors (such as age, gender, other medical conditions, and the type of immunotherapy used to treat the cancer) affect whether a patient with a malignant solid tumor will develop mild or serious side effects from the immunotherapy medications. Immunotherapy is t…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Southern Illinois University School of Medicine, Springfield, Illinois

   Locations

   849 in total

   Run by

   SWOG Cancer Research Network

   See if you can join NCT04871542 on ClinicalTrials.gov

7. Collection and Storage of Tissue and Blood Samples From Patients With Cancer

   This study collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.

   Stage

   Not phased

   Ages

   0 and older

   Site

   Central Illinois Hematology Oncology Center, Springfield, Illinois

   Locations

   140 in total

   Run by

   National Cancer Institute LAO

   See if you can join NCT02474160 on ClinicalTrials.gov

8. A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

   This clinical trial tests the impact of a culturally-tailored home-based physical activity program on physical fitness in Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors. After treatment for cancer, some AYA survivors experience long-term effects from the cance…

   Stage

   Phase 2

   Ages

   15 to 20

   Site

   Southern Illinois University School of Medicine, Springfield, Illinois

   Locations

   77 in total

   Run by

   Children's Oncology Group

   See if you can join NCT06410209 on ClinicalTrials.gov